ID A0A452E2V5_CAPHI Unreviewed; 311 AA.
AC A0A452E2V5;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Leucine rich repeat containing 55 {ECO:0000313|Ensembl:ENSCHIP00000006329.1};
GN Name=LRRC55 {ECO:0000313|Ensembl:ENSCHIP00000006329.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000006329.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000006329.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000006329.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; LWLT01000015; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_017914569.1; XM_018059080.1.
DR RefSeq; XP_017914570.1; XM_018059081.1.
DR AlphaFoldDB; A0A452E2V5; -.
DR STRING; 9925.ENSCHIP00000006329; -.
DR Ensembl; ENSCHIT00000014046.1; ENSCHIP00000006329.1; ENSCHIG00000010200.1.
DR GeneID; 106502927; -.
DR KEGG; chx:106502927; -.
DR CTD; 219527; -.
DR GeneTree; ENSGT00940000161412; -.
DR OMA; WSQLPWP; -.
DR OrthoDB; 3325405at2759; -.
DR Proteomes; UP000291000; Chromosome 15.
DR Bgee; ENSCHIG00000010200; Expressed in testis and 13 other cell types or tissues.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:Ensembl.
DR GO; GO:0099104; F:potassium channel activator activity; IEA:Ensembl.
DR GO; GO:0044325; F:transmembrane transporter binding; IEA:Ensembl.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:Ensembl.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR46473; GH08155P; 1.
DR PANTHER; PTHR46473:SF5; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 55; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF01462; LRRNT; 1.
DR SMART; SM00369; LRR_TYP; 4.
DR SMART; SM00082; LRRCT; 1.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 2.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 271..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 50..82
FT /note="LRRNT"
FT /evidence="ECO:0000259|SMART:SM00013"
FT DOMAIN 209..263
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 311 AA; 33857 MW; A981F285E62A41B1 CRC64;
MGSVQHHCCP QPKMGDASAH RPWPRPPRPA LLLVPLLVAA GVMPSDGGAS CPVLCTCHNQ
AVDCSGQRLF SVPPELPVDT RNLSLAHNRI AAVPPGYLTC YRELRVLSLR NNSLVELPAG
LFLHAKRLAH LDLSYNNLSH VPAGMFQAAH GLLRIDLSHN PGLRRVHPRA FQGLAQLRDL
DLSFGGLAFL SLEALEGLPG LVTLQIGGNP WVCGCTMEPL LKWLRNRIQR CTADSQLAEC
RGPPEVEGAP LFSLTEESFK ACHLTLTLDD YLFIAFVGFV VSIASVATNF LLGITANCCH
RWSKASEEEE I
//
