ID A0A452E6S0_CAPHI Unreviewed; 154 AA.
AC A0A452E6S0;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Inhibitor of DNA binding 1 {ECO:0000313|Ensembl:ENSCHIP00000007668.1};
GN Name=ID1 {ECO:0000313|Ensembl:ENSCHIP00000007668.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000007668.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000007668.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000007668.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; LWLT01000014; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005688507.3; XM_005688450.3.
DR AlphaFoldDB; A0A452E6S0; -.
DR STRING; 9925.ENSCHIP00000007668; -.
DR Ensembl; ENSCHIT00000015416.1; ENSCHIP00000007668.1; ENSCHIG00000011101.1.
DR GeneID; 102182889; -.
DR KEGG; chx:102182889; -.
DR CTD; 3397; -.
DR GeneTree; ENSGT00940000161109; -.
DR OMA; QMNVFLQ; -.
DR OrthoDB; 4207391at2759; -.
DR Proteomes; UP000291000; Chromosome 13.
DR Bgee; ENSCHIG00000011101; Expressed in descending colon and 18 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0140416; F:transcription regulator inhibitor activity; IEA:Ensembl.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR CDD; cd19691; bHLH_dnHLH_ID1; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR026052; DNA-bd_prot-inh.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR PANTHER; PTHR11723; DNA-BINDING PROTEIN INHIBITOR; 1.
DR PANTHER; PTHR11723:SF4; DNA-BINDING PROTEIN INHIBITOR ID-1; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000291000}.
FT DOMAIN 52..104
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
SQ SEQUENCE 154 AA; 16008 MW; 456CC0B331821FAB CRC64;
MKVASGSTAA AAGPSCALKA GKTAGGAGEV VRCLSEQSVA ISRCAGGPGA RLPALLEEQP
VNVLLYDMNG CYSRLKELVP TLPQNRKVSR VEILQHVIDY IWDLELELNS ESRVGTPGGR
GLPARAPLST LNGEIGALAA EAACVPADDR ILCR
//
