ID A0A452E8R2_CAPHI Unreviewed; 538 AA.
AC A0A452E8R2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Tripartite motif-containing protein 26 {ECO:0000256|ARBA:ARBA00039446};
DE AltName: Full=Zinc finger protein 173 {ECO:0000256|ARBA:ARBA00041435};
GN Name=TRIM26 {ECO:0000313|Ensembl:ENSCHIP00000008322.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000008322.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000008322.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000008322.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; LWLT01000028; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A452E8R2; -.
DR Ensembl; ENSCHIT00000016081.1; ENSCHIP00000008322.1; ENSCHIG00000011531.1.
DR GeneTree; ENSGT00940000158668; -.
DR Proteomes; UP000291000; Chromosome 23.
DR Bgee; ENSCHIG00000011531; Expressed in spleen and 18 other cell types or tissues.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19765; Bbox2_TRIM10-like; 1.
DR CDD; cd16598; RING-HC_TRIM26_C-IV; 1.
DR CDD; cd15826; SPRY_PRY_TRIM15; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF369; TRIPARTITE MOTIF-CONTAINING PROTEIN 26; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 16..57
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 97..138
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 292..538
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 373..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 196..223
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 538 AA; 61441 MW; 6291FD5AC872400E CRC64;
MATSAPLRSL EEEVTCSICL DYLRDPVTID CGHVFCRSCT TDIRPISGGR PACPLCKKPF
KKENIRPVWQ LASLVENIER LKVDGGRQPG EAAQEQVDAR LCERHQEKLH YFCEDDGKLL
CVMCRESREH RPHSAVLVEK AAQPHREKIL NHLSILRRDR DKIQGFQAKG EADILAALKK
LQDQRQCIVA EFEQGHQFLR EREQHLLGQL AKLEQELTEG REKFKTRGVG ELARLAQVIS
ELEGKVQQPA AELMQDTRDF LNRYPRKKFW IGKPIARVVK KKTGEFSDKL QSLQRGLREF
QGKGWGGSCV SVTLDPQSAS GYLQLSEDWK CVTYSGLYQG AYLYPQQFDC EPGVLGSKGF
TWGKVYWEVE VEREGWSEDE DEGDEVEEGE EEEEEEEAGY RDGYDDWETD EDEESLGDEE
EEAEEEEEEE EVLESCLVGV ARDSVKRKGD LSLRPEDGVW ALRLSSAGIW ANTSPEAELF
PALRPRRVGI ALDYEGGTVT FTNAESQELI YTFTATFTRR LLPFLWLKWP GTRLLLRP
//
