ID A0A452E8X3_CAPHI Unreviewed; 200 AA.
AC A0A452E8X3;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Rho GDP dissociation inhibitor beta {ECO:0000313|Ensembl:ENSCHIP00000008600.1};
GN Name=ARHGDIB {ECO:0000313|Ensembl:ENSCHIP00000008600.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000008600.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000008600.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000008600.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the Rho GDI family.
CC {ECO:0000256|ARBA:ARBA00009758}.
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DR EMBL; LWLT01000005; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_017903928.1; XM_018048439.1.
DR AlphaFoldDB; A0A452E8X3; -.
DR SMR; A0A452E8X3; -.
DR STRING; 9925.ENSCHIP00000008600; -.
DR Ensembl; ENSCHIT00000016362.1; ENSCHIP00000008600.1; ENSCHIG00000011740.1.
DR GeneID; 108636040; -.
DR CTD; 397; -.
DR GeneTree; ENSGT00390000006233; -.
DR OMA; YKPTAAK; -.
DR OrthoDB; 21211at2759; -.
DR Proteomes; UP000291000; Chromosome 5.
DR Bgee; ENSCHIG00000011740; Expressed in thymus and 18 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0003924; F:GTPase activity; IEA:Ensembl.
DR GO; GO:0005094; F:Rho GDP-dissociation inhibitor activity; IEA:Ensembl.
DR GO; GO:0031267; F:small GTPase binding; IEA:Ensembl.
DR GO; GO:1901164; P:negative regulation of trophoblast cell migration; IEA:Ensembl.
DR GO; GO:0035023; P:regulation of Rho protein signal transduction; IEA:Ensembl.
DR GO; GO:0007266; P:Rho protein signal transduction; IEA:InterPro.
DR Gene3D; 2.70.50.30; Coagulation Factor XIII, subunit A, domain 1; 1.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR000406; Rho_GDI.
DR InterPro; IPR024792; RhoGDI_dom_sf.
DR PANTHER; PTHR10980; RHO GDP-DISSOCIATION INHIBITOR; 1.
DR PANTHER; PTHR10980:SF15; RHO GDP-DISSOCIATION INHIBITOR 2; 1.
DR Pfam; PF02115; Rho_GDI; 1.
DR PRINTS; PR00492; RHOGDI.
DR SUPFAM; SSF81296; E set domains; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000}.
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 200 AA; 22806 MW; EE9FF03A56E5DC28 CRC64;
MTEKAPEPHV EEDDDELDGK LNYKPPPQKS LKELQEMDKD DESLIKYKKT LLGDGPVVAD
PTAPNVTVTR LTLVCESAPG PITMDLTGDL EALKKETFVL KEGVEYRVKI NFKVNKDIVS
GLKYVQHTYR TGVKVDKATF MVGSYGPRPE EYEFLTPIEE APKGMLARGT YHNKSFFTDD
DKHDHLTWEW NLSIKKDWTE
//
