ID A0A452E910_CAPHI Unreviewed; 413 AA.
AC A0A452E910;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=HSF-type DNA-binding domain-containing protein {ECO:0000259|SMART:SM00415};
GN Name=LOC108634541 {ECO:0000313|Ensembl:ENSCHIP00000008478.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000008478.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000008478.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the HSF family. {ECO:0000256|ARBA:ARBA00006403,
CC ECO:0000256|RuleBase:RU004020}.
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DR RefSeq; XP_017899976.1; XM_018044487.1.
DR AlphaFoldDB; A0A452E910; -.
DR Ensembl; ENSCHIT00000016239.1; ENSCHIP00000008478.1; ENSCHIG00000011649.1.
DR GeneID; 108634541; -.
DR KEGG; chx:108634541; -.
DR GeneTree; ENSGT00940000157452; -.
DR OMA; ANDRIMN; -.
DR OrthoDB; 5358111at2759; -.
DR Proteomes; UP000291000; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000232; HSF_DNA-bd.
DR InterPro; IPR027725; HSF_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10015; HEAT SHOCK TRANSCRIPTION FACTOR; 1.
DR PANTHER; PTHR10015:SF336; HEAT SHOCK TRANSCRIPTION FACTOR, Y-LINKED; 1.
DR Pfam; PF00447; HSF_DNA-bind; 1.
DR SMART; SM00415; HSF; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000}.
FT DOMAIN 75..193
FT /note="HSF-type DNA-binding"
FT /evidence="ECO:0000259|SMART:SM00415"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 413 AA; 46847 MW; 2540DF769272BE99 CRC64;
MAHISSEIQD GPPKNESAGS ETSIRPSLYD YTIGDSVLRS MIEEYAFQAL SEDLVIKRPR
YTYSVSQTDD VNDFLSLTFP QKLWNIVESD QFESIWWDET GTCIVINEEL FKKEVLERKD
PFRIFETKSM KSLIRQLNLY GFHKNRQTVQ RSASLPVFLE EENNISLLRK LQTYYNPNFK
RGHPQLLARM QRRVGINNVS PISSLVQGNK KHAKVSVKKD DHNSEFLPEM SGESAFPAST
SLSVPFIQKP HTSQVVANTR ALSPCDLPTP SAISVRHTDQ IVVDQSEVLK KLSILNWHSQ
SRYTQVNGHV EDFATTTTST SGNHIVSPLQ SSYSGLMVEP SKFPDRHSDM SAHDSPFLNL
QERGNSWFSV PTIAYTSASS LSSILINNHQ YVKTILIKTD LPNRYQIMEP KGD
//
