ID A0A452EAS2_CAPHI Unreviewed; 390 AA.
AC A0A452EAS2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Serpin domain-containing protein {ECO:0000259|SMART:SM00093};
GN Name=LOC108633803 {ECO:0000313|Ensembl:ENSCHIP00000009260.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000009260.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000009260.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000009260.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the serpin family. Ov-serpin subfamily.
CC {ECO:0000256|ARBA:ARBA00006426}.
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DR EMBL; LWLT01000023; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_017895161.1; XM_018039672.1.
DR AlphaFoldDB; A0A452EAS2; -.
DR Ensembl; ENSCHIT00000017032.1; ENSCHIP00000009260.1; ENSCHIG00000012186.1.
DR GeneID; 108633803; -.
DR KEGG; chx:108633803; -.
DR GeneTree; ENSGT00940000154520; -.
DR OMA; GHSAYIG; -.
DR OrthoDB; 3218836at2759; -.
DR Proteomes; UP000291000; Chromosome 24.
DR Bgee; ENSCHIG00000012186; Expressed in rumen and 13 other cell types or tissues.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd19956; serpinB; 1.
DR Gene3D; 2.30.39.10; Alpha-1-antitrypsin, domain 1; 1.
DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 1.
DR InterPro; IPR023795; Serpin_CS.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR000215; Serpin_fam.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR InterPro; IPR042185; Serpin_sf_2.
DR PANTHER; PTHR11461; SERINE PROTEASE INHIBITOR, SERPIN; 1.
DR PANTHER; PTHR11461:SF186; SERPIN B4; 1.
DR Pfam; PF00079; Serpin; 1.
DR SMART; SM00093; SERPIN; 1.
DR SUPFAM; SSF56574; Serpins; 1.
DR PROSITE; PS00284; SERPIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000291000}.
FT DOMAIN 13..390
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
SQ SEQUENCE 390 AA; 44012 MW; 430254C6C6B0B48A CRC64;
MSSLGEAIIH LAIDLFHQIR QSEKENIFYS PFSISSALAM TYLGARENTA SEMQKVLHFS
EIAANTKEGA AKDPVEKPGS VHHHFQNLLM ELKKSTDTYE LRVANRLYGE KDFPFLQEYM
DNVQKYYLAS VESADFVSAA EESRKMINCW VECETNGRIK NLFPQNSLDG SVLVLVNAVY
FKGQWQEEFK KENTVEEKFW LNKDTSKPVQ MMKQTNRFNV VSLEDVQAKI LEIPYKGGEL
SMLVLLPREA DGLQEVEDQL TAEKLIAWTS PQNMGKRQVD LHLPRFKVEE SYALVPTLQA
LGMVDAFRGG AADFSGMTGR RDLVVSKVFH KCFVEVTEEG TEAAAATGVG DSVVTSLPFH
ESFRCDHPFL FLIKHIKTNS ILFCGRVSSP
//
