ID A0A452ECG4_CAPHI Unreviewed; 3055 AA.
AC A0A452ECG4;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 10-FEB-2021, entry version 11.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCHIP00000009702};
GN Name=CENPF {ECO:0000313|Ensembl:ENSCHIP00000009702};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000009702, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000009702, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000009702}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2019) to UniProtKB.
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DR EMBL; LWLT01000016; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSCHIT00000017475; ENSCHIP00000009702; ENSCHIG00000012476.
DR GeneTree; ENSGT00730000111187; -.
DR OMA; YNAQLVQ; -.
DR Proteomes; UP000291000; Chromosome 16.
DR GO; GO:0097539; C:ciliary transition fiber; IEA:Ensembl.
DR GO; GO:0000940; C:condensed chromosome outer kinetochore; IEA:Ensembl.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0030496; C:midbody; IEA:Ensembl.
DR GO; GO:0005635; C:nuclear envelope; IEA:Ensembl.
DR GO; GO:0016363; C:nuclear matrix; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0000922; C:spindle pole; IEA:Ensembl.
DR GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0008022; F:protein C-terminus binding; IEA:Ensembl.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR GO; GO:0008134; F:transcription factor binding; IEA:Ensembl.
DR GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR GO; GO:0051310; P:metaphase plate congression; IEA:Ensembl.
DR GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 4.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 4.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000}.
FT DOMAIN 1..307
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 1889..2032
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2095..2234
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2277..2416
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2440..2555
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2911..2954
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 210..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 463..493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1243..1262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1659..1689
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1717..1740
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2833..3055
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 13..131
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 164..191
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 280..384
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 523..699
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 725..752
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 839..873
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 899..957
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 969..989
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1036..1056
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1089..1109
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1118..1159
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1284..1325
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1395..1422
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1547..1617
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1790..1817
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1825..1852
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1886..1913
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1949..2042
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2071..2098
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2106..2242
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2260..2280
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2288..2424
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2442..2549
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2559..2618
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2630..2657
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2680..2766
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2777..2804
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 475..493
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1669..1689
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2833..2847
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2859..2873
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2881..2895
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2896..2912
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2940..2954
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2969..3019
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3055 AA; 350166 MW; 9CC4C663AABDE3A4 CRC64;
MSWALEEWKE GLPTRALQKI QELEGQLDKL KKERQQRQFQ LDTLEAALQK QKQKIENEKT
EGANLKRENQ SLMEICENLE KTKQKISHEL QVKESQVNFQ EGQLNSSKKQ IEKLEQELKR
CKSELERSQQ VAQSADVSLN SCLTPQKIFA TPLTPSQYYS GSKYEDLKEK YNKEVEERKR
LEAEVKALQA KKASQAIPQS TMNHRDIARH QASSSVFSWQ QEKTPSRLSS NTLKTPVRRD
FSASHFSGEQ EVTPSRSTLQ IGKTDANSSF CDNSSNSHLL DQLKAQNQEL RSKISELELC
LQGQEKEMKG QVNKLQELQL QLEKAKVELN EKEKVLNKTR DELVRTTSQY DQASTKCTAL
EQKLKKLTED LSCQRQNAES ARCSLEQKIK EKEKEFQEEL SRQQRSFQTL DQECTQMKAR
LTQELQQAKN TYNILQAELD KVTSVKHQVE KKLEEFKQNL SKTEQALQAS QTKENELRRS
SEEMKRENSL LKSQSEQRAR EVCHLEEELK KAKQCLSQSQ NFAEEMKAKN TSQETMLRDL
QEKINQQENS LTLEKLKLAL ADLEKQRDCS QDLLKKREHH IEQLNEKLSK TERESEALLS
ALELKKKEYE ELKEEKTLFS RWKRENEQLL SQMESEKESL QSKVNHLETC LKTQQIKSHE
YNERVRTLEM ERENLNVEIR NLQNVIDSKT TEAETQKRAY GELQQKAEFS DQKHEKEIEN
MCLKISHLTG QVEDLEHKLQ LLSSEIMDKD QRYQDLHAEY ESLRDLLKSR DSSAVTIEPH
QRSRLAFEQQ SALNNFFASI IGEQESVSSE RSGCHVATDQ SPEGSSMLQN RVVSLEFSLE
SQKQMNSDLQ KQCEELVQIK GEIEENLMKA EQMHQSFMAE TSQRISKLQE DTSVHQNVVA
ETLAALESKE RELQLLNEKL ETEQAEIGEL KKNNHLLQES LKELQFLSET LSLEKKELNS
IISLNKKDIE GLTQENGTLK EINATLTQEK MNLLQKTESF SNCIDERDKS ISELSNQYKQ
ERLTLLQRCE ETGNAFQDLS EKYKAVQEKN SKLECLLSEC TGVCEDRKNE LGQLKETFAR
EHQAFVSQLA SAEERNQNLI LELETVQQAL QSEITDIQNS SKREADGLKQ EIMKLKEEQN
KMQQEVNALL QENEHLMELM KTKHEHQCLE LEPIQDSEKE GEREINTCHV QLPMDLDVKD
TSLDTYKAQL VQGESEVRNM ELRLQKSEKE ECLQHELQAR ELETEDLQQD TQSQDISSLG
DSEIDPEEKY ISVLHELSTS QQDNAHLQCS LQTAMNKLNE LEKMCEALQV EKSELISELN
DSRSECITAT GKMAEEVGKL VKEVETLNDE NGLLQGELVE ETPEGEFGEQ QDEQTSVNLN
PLDDCNFYEH LTMSNKEVQM HFAELQEKFS SLQSEHKILH EQHCLMSSKM SELQSYVDTL
KAENSVLSMS LRSAQGDLVK EVTPAPGEEH SLSLSFSCVT DSPGNASLGE SSFYKDLLEH
TTETSLLNNL EGTVSANQSS VEEVSCSSLE EENLTEKEIP SVPLRSTREL ETLCQTYLQS
LKQLEEEIES QGLTKNKEIE ELKELLSSSR EELDYLRKQY LSENEQWQQK LTDVTAEMES
KLAAEKRHTE HLTLELEVAR LQLQGLDLSS RSLLGTDVED AIPGGNDSCD IRESEEYTSE
PKERTPKHEI HQVCEKDVQQ DLSLEMEKIT KTAAAKLTEE WSRERSSEAS PEAPVGDPAQ
GCSKCISELS LPGPNASVPR DVLENQVTIQ SLELKVKETS NENLRLLHGI EERDQKVDNL
LNEIKELDSK FHLLEVQLTT KIEACVALEK IVEELKKEKL DLNEKLASFS CHNQREESSG
GLTPSLEMVT SKLPHEDIED DVAKVTDNWR EKCLQVENEL QRIQSEKDSM EHHTLSAEAS
LEAVQTEKLY LEKDNENKQT VITCLEEGLS VVTSERDQLR GELDTLSKEN QELDQMSEKM
KEKIRELESH QSECLHLQEQ LQSLEKDSQA LSLVKSELEN QIEQLNKEKD SLVWESESLQ
TKLSESENEK LAITKALETA LMEKGEVAVR LSSTQEEVHQ LRKGIEKLRV RIEADEKKQL
HVSEKLKASE RRNDSLQDKV ETLERELQMA EENQELVILD AENCKAEVET LKTQIELMTE
RLKDLESDLV TIRTEKENLL KQLQEKQGQA SELDTLLSSL KNLLEEKEQE KIQMKEESKA
AVEMLQTQLR ELSEEVAALC DDQEICKVKE QSLDSPAQEV QQLRNNIEKL KLHLDIDKKQ
QLHILEKLKE SQHQADLLKD TVENLERELK LSGENQEHVT LEAEKSKAEV ETLKATAEEM
DQNLRGLQLD LVNIRSEKED LTKELLKEQS RVSELQTLNS SFENLLREKE QEKVQMKEES
KAAVEMLQTQ LKELSEEVAT LYVDQETWKV EEQSLDSPVE EVQQLRNNLG KLKDTVENLE
RELELSGKNQ EHAEKSKAEV ETLKTTMEEM DQNLRGLQLD LVNIRSEKED LTKELQKEQS
RVSELETLNS SFENMLREKE QEKVQMQEES KVNAMTVKET ELQKEMHAMI QKTAELKEEF
SGEKNRLTEE LNLMLEEVKS SKGQLNELML ENSELKKSLD CVHKGHMEEQ GKMRGEIAEY
QLRLQEAENK HQALLLDTNK QHEMEIQTYR EKLTSKEECL SSQKVEIDLL KSSKEELNNS
LKATTEILEE LKKTKMENLK HADKLKKEND RAQSKIKLLM KSCKQLEEEK VMLQKELSHL
EAAQEKQRAD TVLDANVDEL ITEMKELKES LEEKTKEADE YLEKYCSLLI SHEKLEKAKE
MLETQVARLS SQQSKLNLRS SPLVNSVAPG PSPVPSATEK KLPSGQNKSS GKRQRSSGIR
EDGGETTPST PETFSKKSRK AIKSGTHPPE DAEDAEFEPE GLPEVVKKGF ADIPTGKTSP
YILRRTTMAT RTSPRLAAQK LAASPLSLDK ENLTETSKPT AGGSRSQKVK VSQQSPVDSG
TTFRDPTARS LSISNLPERS PAGSPREGLR AKRGHHAPSP EASLQSKGSE NCRVQ
//
