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Database: UniProt
Entry: A0A452ECG4_CAPHI
LinkDB: A0A452ECG4_CAPHI
Original site: A0A452ECG4_CAPHI 
ID   A0A452ECG4_CAPHI        Unreviewed;      3055 AA.
AC   A0A452ECG4;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   10-FEB-2021, entry version 11.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCHIP00000009702};
GN   Name=CENPF {ECO:0000313|Ensembl:ENSCHIP00000009702};
OS   Capra hircus (Goat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Caprinae; Capra.
OX   NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000009702, ECO:0000313|Proteomes:UP000291000};
RN   [1] {ECO:0000313|Ensembl:ENSCHIP00000009702, ECO:0000313|Proteomes:UP000291000}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA   Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA   Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA   Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA   Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT   "Polished mammalian reference genomes with single-molecule sequencing and
RT   chromosome conformation capture applied to the Capra hircus genome.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCHIP00000009702}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAR-2019) to UniProtKB.
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DR   EMBL; LWLT01000016; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSCHIT00000017475; ENSCHIP00000009702; ENSCHIG00000012476.
DR   GeneTree; ENSGT00730000111187; -.
DR   OMA; YNAQLVQ; -.
DR   Proteomes; UP000291000; Chromosome 16.
DR   GO; GO:0097539; C:ciliary transition fiber; IEA:Ensembl.
DR   GO; GO:0000940; C:condensed chromosome outer kinetochore; IEA:Ensembl.
DR   GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR   GO; GO:0030496; C:midbody; IEA:Ensembl.
DR   GO; GO:0005635; C:nuclear envelope; IEA:Ensembl.
DR   GO; GO:0016363; C:nuclear matrix; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0000922; C:spindle pole; IEA:Ensembl.
DR   GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0008022; F:protein C-terminus binding; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0051310; P:metaphase plate congression; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR   GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 4.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 4.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000291000}.
FT   DOMAIN          1..307
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1889..2032
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2095..2234
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2277..2416
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2440..2555
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2911..2954
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          210..234
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          463..493
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1243..1262
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1659..1689
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1717..1740
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2833..3055
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          13..131
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          164..191
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          280..384
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          523..699
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          725..752
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          839..873
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          899..957
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          969..989
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1036..1056
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1089..1109
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1118..1159
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1284..1325
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1395..1422
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1547..1617
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1790..1817
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1825..1852
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1886..1913
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1949..2042
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2071..2098
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2106..2242
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2260..2280
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2288..2424
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2442..2549
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2559..2618
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2630..2657
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2680..2766
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2777..2804
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        475..493
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1669..1689
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2833..2847
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2859..2873
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2881..2895
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2896..2912
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2940..2954
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2969..3019
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   3055 AA;  350166 MW;  9CC4C663AABDE3A4 CRC64;
     MSWALEEWKE GLPTRALQKI QELEGQLDKL KKERQQRQFQ LDTLEAALQK QKQKIENEKT
     EGANLKRENQ SLMEICENLE KTKQKISHEL QVKESQVNFQ EGQLNSSKKQ IEKLEQELKR
     CKSELERSQQ VAQSADVSLN SCLTPQKIFA TPLTPSQYYS GSKYEDLKEK YNKEVEERKR
     LEAEVKALQA KKASQAIPQS TMNHRDIARH QASSSVFSWQ QEKTPSRLSS NTLKTPVRRD
     FSASHFSGEQ EVTPSRSTLQ IGKTDANSSF CDNSSNSHLL DQLKAQNQEL RSKISELELC
     LQGQEKEMKG QVNKLQELQL QLEKAKVELN EKEKVLNKTR DELVRTTSQY DQASTKCTAL
     EQKLKKLTED LSCQRQNAES ARCSLEQKIK EKEKEFQEEL SRQQRSFQTL DQECTQMKAR
     LTQELQQAKN TYNILQAELD KVTSVKHQVE KKLEEFKQNL SKTEQALQAS QTKENELRRS
     SEEMKRENSL LKSQSEQRAR EVCHLEEELK KAKQCLSQSQ NFAEEMKAKN TSQETMLRDL
     QEKINQQENS LTLEKLKLAL ADLEKQRDCS QDLLKKREHH IEQLNEKLSK TERESEALLS
     ALELKKKEYE ELKEEKTLFS RWKRENEQLL SQMESEKESL QSKVNHLETC LKTQQIKSHE
     YNERVRTLEM ERENLNVEIR NLQNVIDSKT TEAETQKRAY GELQQKAEFS DQKHEKEIEN
     MCLKISHLTG QVEDLEHKLQ LLSSEIMDKD QRYQDLHAEY ESLRDLLKSR DSSAVTIEPH
     QRSRLAFEQQ SALNNFFASI IGEQESVSSE RSGCHVATDQ SPEGSSMLQN RVVSLEFSLE
     SQKQMNSDLQ KQCEELVQIK GEIEENLMKA EQMHQSFMAE TSQRISKLQE DTSVHQNVVA
     ETLAALESKE RELQLLNEKL ETEQAEIGEL KKNNHLLQES LKELQFLSET LSLEKKELNS
     IISLNKKDIE GLTQENGTLK EINATLTQEK MNLLQKTESF SNCIDERDKS ISELSNQYKQ
     ERLTLLQRCE ETGNAFQDLS EKYKAVQEKN SKLECLLSEC TGVCEDRKNE LGQLKETFAR
     EHQAFVSQLA SAEERNQNLI LELETVQQAL QSEITDIQNS SKREADGLKQ EIMKLKEEQN
     KMQQEVNALL QENEHLMELM KTKHEHQCLE LEPIQDSEKE GEREINTCHV QLPMDLDVKD
     TSLDTYKAQL VQGESEVRNM ELRLQKSEKE ECLQHELQAR ELETEDLQQD TQSQDISSLG
     DSEIDPEEKY ISVLHELSTS QQDNAHLQCS LQTAMNKLNE LEKMCEALQV EKSELISELN
     DSRSECITAT GKMAEEVGKL VKEVETLNDE NGLLQGELVE ETPEGEFGEQ QDEQTSVNLN
     PLDDCNFYEH LTMSNKEVQM HFAELQEKFS SLQSEHKILH EQHCLMSSKM SELQSYVDTL
     KAENSVLSMS LRSAQGDLVK EVTPAPGEEH SLSLSFSCVT DSPGNASLGE SSFYKDLLEH
     TTETSLLNNL EGTVSANQSS VEEVSCSSLE EENLTEKEIP SVPLRSTREL ETLCQTYLQS
     LKQLEEEIES QGLTKNKEIE ELKELLSSSR EELDYLRKQY LSENEQWQQK LTDVTAEMES
     KLAAEKRHTE HLTLELEVAR LQLQGLDLSS RSLLGTDVED AIPGGNDSCD IRESEEYTSE
     PKERTPKHEI HQVCEKDVQQ DLSLEMEKIT KTAAAKLTEE WSRERSSEAS PEAPVGDPAQ
     GCSKCISELS LPGPNASVPR DVLENQVTIQ SLELKVKETS NENLRLLHGI EERDQKVDNL
     LNEIKELDSK FHLLEVQLTT KIEACVALEK IVEELKKEKL DLNEKLASFS CHNQREESSG
     GLTPSLEMVT SKLPHEDIED DVAKVTDNWR EKCLQVENEL QRIQSEKDSM EHHTLSAEAS
     LEAVQTEKLY LEKDNENKQT VITCLEEGLS VVTSERDQLR GELDTLSKEN QELDQMSEKM
     KEKIRELESH QSECLHLQEQ LQSLEKDSQA LSLVKSELEN QIEQLNKEKD SLVWESESLQ
     TKLSESENEK LAITKALETA LMEKGEVAVR LSSTQEEVHQ LRKGIEKLRV RIEADEKKQL
     HVSEKLKASE RRNDSLQDKV ETLERELQMA EENQELVILD AENCKAEVET LKTQIELMTE
     RLKDLESDLV TIRTEKENLL KQLQEKQGQA SELDTLLSSL KNLLEEKEQE KIQMKEESKA
     AVEMLQTQLR ELSEEVAALC DDQEICKVKE QSLDSPAQEV QQLRNNIEKL KLHLDIDKKQ
     QLHILEKLKE SQHQADLLKD TVENLERELK LSGENQEHVT LEAEKSKAEV ETLKATAEEM
     DQNLRGLQLD LVNIRSEKED LTKELLKEQS RVSELQTLNS SFENLLREKE QEKVQMKEES
     KAAVEMLQTQ LKELSEEVAT LYVDQETWKV EEQSLDSPVE EVQQLRNNLG KLKDTVENLE
     RELELSGKNQ EHAEKSKAEV ETLKTTMEEM DQNLRGLQLD LVNIRSEKED LTKELQKEQS
     RVSELETLNS SFENMLREKE QEKVQMQEES KVNAMTVKET ELQKEMHAMI QKTAELKEEF
     SGEKNRLTEE LNLMLEEVKS SKGQLNELML ENSELKKSLD CVHKGHMEEQ GKMRGEIAEY
     QLRLQEAENK HQALLLDTNK QHEMEIQTYR EKLTSKEECL SSQKVEIDLL KSSKEELNNS
     LKATTEILEE LKKTKMENLK HADKLKKEND RAQSKIKLLM KSCKQLEEEK VMLQKELSHL
     EAAQEKQRAD TVLDANVDEL ITEMKELKES LEEKTKEADE YLEKYCSLLI SHEKLEKAKE
     MLETQVARLS SQQSKLNLRS SPLVNSVAPG PSPVPSATEK KLPSGQNKSS GKRQRSSGIR
     EDGGETTPST PETFSKKSRK AIKSGTHPPE DAEDAEFEPE GLPEVVKKGF ADIPTGKTSP
     YILRRTTMAT RTSPRLAAQK LAASPLSLDK ENLTETSKPT AGGSRSQKVK VSQQSPVDSG
     TTFRDPTARS LSISNLPERS PAGSPREGLR AKRGHHAPSP EASLQSKGSE NCRVQ
//
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