ID A0A452EDS7_CAPHI Unreviewed; 195 AA.
AC A0A452EDS7;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Antiluteolysin {ECO:0000256|ARBA:ARBA00032691};
DE AltName: Full=Trophoblast antiluteolytic protein {ECO:0000256|ARBA:ARBA00033104};
DE AltName: Full=Trophoblast protein 1 {ECO:0000256|ARBA:ARBA00030373};
DE AltName: Full=Trophoblastin {ECO:0000256|ARBA:ARBA00031375};
GN Name=LOC108636620 {ECO:0000313|Ensembl:ENSCHIP00000010003.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000010003.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000010003.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000010003.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the alpha/beta interferon family. IFN-alphaII
CC subfamily. {ECO:0000256|ARBA:ARBA00006593}.
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DR EMBL; LWLT01000007; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_017908293.1; XM_018052804.1.
DR AlphaFoldDB; A0A452EDS7; -.
DR STRING; 9925.ENSCHIP00000010003; -.
DR Ensembl; ENSCHIT00000017776.1; ENSCHIP00000010003.1; ENSCHIG00000012674.1.
DR GeneID; 108636620; -.
DR KEGG; chx:108636620; -.
DR GeneTree; ENSGT01000000214430; -.
DR OMA; FRFPHAT; -.
DR OrthoDB; 5358931at2759; -.
DR Proteomes; UP000291000; Chromosome 8.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.
DR GO; GO:0005126; F:cytokine receptor binding; IEA:InterPro.
DR GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR GO; GO:0007565; P:female pregnancy; IEA:UniProtKB-KW.
DR CDD; cd00095; IFab; 1.
DR Gene3D; 1.20.1250.10; -; 1.
DR InterPro; IPR009079; 4_helix_cytokine-like_core.
DR InterPro; IPR000471; Interferon_alpha/beta/delta.
DR PANTHER; PTHR11691:SF37; INTERFERON OMEGA-1; 1.
DR PANTHER; PTHR11691; TYPE I INTERFERON; 1.
DR Pfam; PF00143; Interferon; 1.
DR PRINTS; PR00266; INTERFERONAB.
DR SMART; SM00076; IFabd; 1.
DR SUPFAM; SSF47266; 4-helical cytokines; 1.
DR PROSITE; PS00252; INTERFERON_A_B_D; 1.
PE 3: Inferred from homology;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118,
KW ECO:0000256|RuleBase:RU000436}; Cytokine {ECO:0000256|RuleBase:RU000436};
KW Hormone {ECO:0000256|ARBA:ARBA00022702};
KW Pregnancy {ECO:0000256|ARBA:ARBA00022720};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..195
FT /note="Antiluteolysin"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019314605"
SQ SEQUENCE 195 AA; 21959 MW; 6038C0D7F934CCC2 CRC64;
MAFVLSLLMA LVLVSHGPEG SLGCDLSQNH MLVGRKNLRL LGQMRRLSSR FCLQDRKDFA
FPQEMVEGDQ LQEAQAISVL HEMLQQSFNL FHTERTSAAW DTTLLEQLRT GLHQQLDDLD
ACLGQVMGEE DSALGRTGPT LAVKRYFQGI HVYLQEKGYS DCAWEILRVE MMKALSSSTS
LQERLRKMGG DLNSP
//
