ID A0A452EL60_CAPHI Unreviewed; 386 AA.
AC A0A452EL60;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Actin-related protein 2 {ECO:0000256|ARBA:ARBA00021611};
DE AltName: Full=Actin-like protein 2 {ECO:0000256|ARBA:ARBA00042826};
GN Name=ACTR2 {ECO:0000313|Ensembl:ENSCHIP00000012597.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000012597.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000012597.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000012597.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection {ECO:0000256|ARBA:ARBA00004316}.
CC -!- SIMILARITY: Belongs to the actin family. ARP2 subfamily.
CC {ECO:0000256|ARBA:ARBA00010121}.
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DR EMBL; LWLT01000009; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A452EL60; -.
DR Ensembl; ENSCHIT00000020387.1; ENSCHIP00000012597.1; ENSCHIG00000014272.1.
DR GeneTree; ENSGT00940000154556; -.
DR Proteomes; UP000291000; Chromosome 11.
DR Bgee; ENSCHIG00000014272; Expressed in thymus and 17 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR004000; Actin.
DR InterPro; IPR020902; Actin/actin-like_CS.
DR InterPro; IPR043129; ATPase_NBD.
DR PANTHER; PTHR11937; ACTIN; 1.
DR PANTHER; PTHR11937:SF37; ACTIN-RELATED PROTEIN 2; 1.
DR Pfam; PF00022; Actin; 1.
DR PRINTS; PR00190; ACTIN.
DR SMART; SM00268; ACTIN; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000}.
SQ SEQUENCE 386 AA; 43951 MW; 2B26D320EF038133 CRC64;
SLARDGTHFV KCGYAGSNFP EHIFPALVGR PIIRSTTKVG NIEIKDLMVG DEASELRSML
EVNYPMENGI VRNWDDMKHL WDYTFGPEKL NIDTRNCKIL LTEPPMNPTK NREKIVEVMF
ETYQFSGVYV AIQAVLTLYA QGLLTGVVVD SGDGVTHICP VYEGFSLPHL TRRLDIAGRD
ITRYLIKLLL LRGYAFNHSA DFETVRMIKE KLCYVGYNIE QEQKLALETT VLVESYTLPD
GRIIKVGGER FEAPEALFQP HLINVEGVGV AELLFNTIQA ADIDTRSEFY KHIVLSGGST
MYPGLPSRLE RELKQLYLER VLKGDVEKLS KFKIRIEDPP RRKHMVFLGG AVLADIMKDK
DNFWMTRQEY QEKGVRVLEK LGVTVR
//
