ID A0A452EL78_CAPHI Unreviewed; 1548 AA.
AC A0A452EL78;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Thrombospondin type 1 domain containing 7B {ECO:0000313|Ensembl:ENSCHIP00000012674.1};
GN Name=THSD7B {ECO:0000313|Ensembl:ENSCHIP00000012674.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000012674.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000012674.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000012674.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; LWLT01000002; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 9925.ENSCHIP00000012674; -.
DR Ensembl; ENSCHIT00000020465.1; ENSCHIP00000012674.1; ENSCHIG00000014355.1.
DR GeneTree; ENSGT00940000159262; -.
DR Proteomes; UP000291000; Chromosome 2.
DR Bgee; ENSCHIG00000014355; Expressed in cerebellum and 4 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 12.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR InterPro; IPR044004; TSP1_spondin_dom.
DR PANTHER; PTHR11311; SPONDIN; 1.
DR PANTHER; PTHR11311:SF32; TSP1_SPONDIN DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF19030; TSP1_ADAMTS; 4.
DR Pfam; PF19028; TSP1_spondin; 7.
DR Pfam; PF00090; TSP_1; 1.
DR SMART; SM00209; TSP1; 16.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 13.
DR PROSITE; PS50092; TSP1; 12.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1479..1502
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 103..152
FT /note="Spondin-like TSP1"
FT /evidence="ECO:0000259|Pfam:PF19028"
FT DOMAIN 260..312
FT /note="Spondin-like TSP1"
FT /evidence="ECO:0000259|Pfam:PF19028"
FT DOMAIN 525..583
FT /note="Spondin-like TSP1"
FT /evidence="ECO:0000259|Pfam:PF19028"
FT DOMAIN 661..716
FT /note="Spondin-like TSP1"
FT /evidence="ECO:0000259|Pfam:PF19028"
FT DOMAIN 924..969
FT /note="Spondin-like TSP1"
FT /evidence="ECO:0000259|Pfam:PF19028"
FT DOMAIN 1171..1224
FT /note="Spondin-like TSP1"
FT /evidence="ECO:0000259|Pfam:PF19028"
FT DOMAIN 1294..1353
FT /note="Spondin-like TSP1"
FT /evidence="ECO:0000259|Pfam:PF19028"
SQ SEQUENCE 1548 AA; 173006 MW; DB46701045880BC8 CRC64;
MSNCDEHNRP PKERSCFRVC DWHRDLFQWE VSDWHHCVLA PPDLGPARPR AAACVTAQHG
LQHRTVHCVQ KLNRTMVVNE ICEHFAPQPP TEQACLIPCP RDCVVSEFSP WSTCSNGCGK
RLQHRTRSAI ALPLYGGSQC PNLTESRACD APISCPLGAE EYTFSLKVGP WSKCRLPHLK
ELNLSGRTVL DFSSESKELV PFRHHSYKAH HHSKSWDIEI GFQTRQVWCT RSDGRNAVLS
LCMQDSFPLT VQSCIMPKDC ETTEWSSWSP CSKTCRSGSL SPGFRSRSRD VKHIALGGGK
DCPELLEKEA CIVEGELLHL CPRYSWKTSE WKECQVSLLL EQQYLHWHET GPICGGGIQT
REVYCAQSTP ASTAQRAKEV SRPVAKTLCL GPAPSASQLC STPCSTDCIM SSWSAWGLCV
HENCRDPQGR KGFRMRQRHV LMESTGPAGR CPHLVESVPC EDPVCYQWLV SEGICIPDHG
KCGPGHRILK AVCQNEQGED VSGSLCPASP PPEQMACEIP CRMDCVVSEW TEWSSCSQSC
SNKNSDGKQT RSRTILALAG EGGKPCPPSQ ALQEYRSCND HSCMQLYWET SPWGPCSEDT
LVTALNATIG WNGEATCGVG IQTRRVFCVK SHVGQVMTKR CPESTRPETV RACLLPCKKD
CLVTAFSEWT PCPRLCQPGN TTIKQSRYRI IIQEAANGGQ ECPDTLFEER ECEDVSLCST
YRWRPQKWSP CVLVPESVRQ GVMGTSETCG KGVQTRAVSC ISDNNQSAEM TECLRQINGM
PPLMQECIVP CRDDCTFTAW SKFTPCSTNC ETTRSRRRQL TGKSRKKEKC QDTDLYPLVE
TEPCPCDVFT SHPYGNWSDC ILPESRKEPH RGLRLQGDAK ECGEGLRFRA VACSDKNGRP
VDPVHCNSSG YIQEECVIPC PFDCKLSDWS SWGSCSSSCG IGVRIRSRWL KEKPYNGGRP
CPKLDLKNQV HEAVPCYTEC NQYSWVVEHW SPCKIHNELR SLRCGGGTQS RKIRCMNAAD
GEGGAVDNSL CNQDEIPPET QSCSLLCPNE CVMSEWGPWS KCPQSCDPHT MQRRTRHLLR
PSLSSRTCAE DSQVRPCLLN ENCFQFQYNL TEWSTCQLSE NATCGQGIRT RLLSCVRSDG
KPVAMDECEQ RNLEKPQRMN LHCLVECVVN CQLSGWTAWT ECSQTCGLRG QRSRTRFILM
PTQGEGRPCP TELTQHKTCP MTPCYSWVLS NWSACKLEGG DCGEGVQTRS LSCVVHNGSI
SPWTVRVDDA LCREMPFQDS ILKQPCSVPC PGDCHLTEWS EWSTCELTCI DGRSFETLGR
QSRSRTFIIQ SFENQDSCPQ QVLETRPCTG GKCYHYTWKA SLWNNNERTV WCQRSDGINV
TGGCSLQARP AAIRQCNPAC RKPFSYCTQG GVCGCEKGYT EIMRSNGLLD YCMKVPGSED
KKADVKNLAG KNRPVNSKIH DIFKGWSLQP LDPDGRVKIW VYGVSGGGFL IMIFLVFTSY
LVCPFKCRLV CSGPKLEPGS VTRATGFYIY INIDKFGCYS DNYAVPAL
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