ID A0A452EMJ3_CAPHI Unreviewed; 799 AA.
AC A0A452EMJ3;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=BICD cargo adaptor 1 {ECO:0000313|Ensembl:ENSCHIP00000013271.1};
GN Name=BICD1 {ECO:0000313|Ensembl:ENSCHIP00000013271.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000013271.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000013271.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000013271.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the BicD family.
CC {ECO:0000256|ARBA:ARBA00010061}.
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DR EMBL; LWLT01000005; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A452EMJ3; -.
DR STRING; 9925.ENSCHIP00000013271; -.
DR Ensembl; ENSCHIT00000021063.1; ENSCHIP00000013271.1; ENSCHIG00000014760.1.
DR GeneTree; ENSGT00940000154471; -.
DR OMA; KAEHDCE; -.
DR Proteomes; UP000291000; Chromosome 5.
DR Bgee; ENSCHIG00000014760; Expressed in prefrontal cortex and 12 other cell types or tissues.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0005881; C:cytoplasmic microtubule; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0016020; C:membrane; IEA:Ensembl.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR GO; GO:0099503; C:secretory vesicle; IEA:Ensembl.
DR GO; GO:0005802; C:trans-Golgi network; IEA:Ensembl.
DR GO; GO:0008093; F:cytoskeletal anchor activity; IEA:Ensembl.
DR GO; GO:0034452; F:dynactin binding; IEA:Ensembl.
DR GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:Ensembl.
DR GO; GO:0019901; F:protein kinase binding; IEA:Ensembl.
DR GO; GO:0031267; F:small GTPase binding; IEA:Ensembl.
DR GO; GO:0072385; P:minus-end-directed organelle transport along microtubule; IEA:Ensembl.
DR GO; GO:1904781; P:positive regulation of protein localization to centrosome; IEA:Ensembl.
DR GO; GO:0048260; P:positive regulation of receptor-mediated endocytosis; IEA:Ensembl.
DR GO; GO:0033365; P:protein localization to organelle; IEA:Ensembl.
DR GO; GO:0070507; P:regulation of microtubule cytoskeleton organization; IEA:Ensembl.
DR GO; GO:0016032; P:viral process; IEA:Ensembl.
DR Gene3D; 6.10.250.2470; -; 1.
DR InterPro; IPR018477; BICD.
DR PANTHER; PTHR31233; BICAUDAL D FAMILY MEMBER; 1.
DR PANTHER; PTHR31233:SF3; PROTEIN BICAUDAL D HOMOLOG 1; 1.
DR Pfam; PF09730; BicD; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000}.
FT REGION 510..581
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 75..224
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 285..330
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 385..437
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 632..751
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 556..577
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 799 AA; 91609 MW; 821EB2E3D27D3147 CRC64;
EQNLAARFAD RARKSVYTTT HNGVFHFVFF LFPNPLQAFG QSFSIHRKVA EDGETREETL
LQESASKEAY YLGKILDMQN ELKQSRAVVT NVQAENERLT AVVQDLKENN EMGELQRIRM
KDEIREYKFR EARLLQDYTE LEEENITLQK LVSTLKQNQV EYEGLKHEIK RFEEETVLLN
SQLEDAIRLK EIAEHQLEEA LETLKNEREQ KNSLRKELSQ YITLNDNHIS ISVDGLKFAE
DGSEPNNDDK MNGHIHGPLV KLNGDYRTPT LRKGESLHPV SDLFSELNIS EIQKLKQQLM
QVEREKAILL ANLQESQTQL EHTKGALTEQ HERVHRLTEH VNAMRGLQSS KELKELDGEK
GRDSGEEAHD YEVDINGLEI LECKYRVAVT EVIDLKAEIK ALKEKYNKSI ENYTEEKAKY
ESKIQMYDEQ VTSLEKTTKE SGEKMAHMEN ELQKMTSIAN ENHSTLNTAQ DELVTFSEEL
AQLYHHVCLC NNETPNRVML DYYRQSRVTR SGSLKGPDDP RGLLSPRLVR RGVSSPVETR
TSPEPVSKEN TEASKEPSPT KTPTVSPVIT APPSSPVLDT SDIRKEPMNI YNLNAIIRDQ
IKHLQKAVDR SLQLSRQRAA ARELAPMIDK DKEALMEEIL KLKSLLSTKR EQIATLRAVL
KANKQTAEVA LANLKNKYEN EKAMVTETMT KLRNELKALK EDAATFSSLR AMFATRCDEY
VTQLDEMQRQ LAAAEDEKKT LNTLLRMAIQ QKLALTQRLE DLEFDHEQSR RSKGKLGKSK
IGSPKPLLIC AYQHAHNLF
//
