ID A0A452EQP2_CAPHI Unreviewed; 457 AA.
AC A0A452EQP2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Methionyl-tRNA formyltransferase, mitochondrial {ECO:0000256|ARBA:ARBA00014185};
DE EC=2.1.2.9 {ECO:0000256|ARBA:ARBA00012261};
GN Name=MTFMT {ECO:0000313|Ensembl:ENSCHIP00000014400.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000014400.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000014400.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000014400.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the Fmt family. {ECO:0000256|ARBA:ARBA00010699}.
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DR EMBL; LWLT01000010; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A452EQP2; -.
DR STRING; 9925.ENSCHIP00000014400; -.
DR Ensembl; ENSCHIT00000022195.1; ENSCHIP00000014400.1; ENSCHIG00000015447.1.
DR GeneTree; ENSGT00390000017828; -.
DR Proteomes; UP000291000; Chromosome 10.
DR Bgee; ENSCHIG00000015447; Expressed in thymus and 17 other cell types or tissues.
DR GO; GO:0004479; F:methionyl-tRNA formyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd08646; FMT_core_Met-tRNA-FMT_N; 1.
DR Gene3D; 3.40.50.12230; -; 1.
DR InterPro; IPR005794; Fmt.
DR InterPro; IPR005793; Formyl_trans_C.
DR InterPro; IPR002376; Formyl_transf_N.
DR InterPro; IPR036477; Formyl_transf_N_sf.
DR InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR InterPro; IPR041711; Met-tRNA-FMT_N.
DR NCBIfam; TIGR00460; fmt; 1.
DR PANTHER; PTHR11138; METHIONYL-TRNA FORMYLTRANSFERASE; 1.
DR PANTHER; PTHR11138:SF5; METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF02911; Formyl_trans_C; 1.
DR Pfam; PF00551; Formyl_trans_N; 1.
DR SUPFAM; SSF50486; FMT C-terminal domain-like; 1.
DR SUPFAM; SSF53328; Formyltransferase; 1.
PE 3: Inferred from homology;
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 188..291
FT /note="Formyl transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00551"
FT DOMAIN 314..420
FT /note="Formyl transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02911"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..48
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 457 AA; 50556 MW; BFB2B921DD198295 CRC64;
MGHASNQASH APAGERPRRT SSPRPRPSGP APPAPPLRPR PSGPAPPAWR RRPHRSAPAQ
GRPPAEEMRV LVRCCCGHLP VGGGAGRRPS PRWRALARLS ASPGWEDGQG AQVREKPPWR
VLFFGTDQFA RETLRALHAA RENKEEELIE KLEVVTVPSP SPKGLPVKQY AVQSQLPVYE
WPDVGSGEYD VGVVASFGRL LSEALILKFP YGILNVHPSC LPRWRGPAPI IHTILHGDTI
AGVTIMQIKP KRFDVGPILK QETVPVPPKS TSKELEAVLS RLGANMLISV LKNLPESLNN
GRQQPAEGVT HAPKISAATS CIKWEEQTSE QIFRLYRAVG NIIPLQTLWM DNTIKLLDLV
EVDSSILSDS KLTGQAVIPG SVIYHKQSQI LLVCCKDDWI GVRSVMLKKT LTATDFYNGY
LHPWYQKNSQ AQPSQCRFQT LRLPPKKKKQ KKKIVAM
//
