ID A0A452ERJ8_CAPHI Unreviewed; 3885 AA.
AC A0A452ERJ8;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Bassoon presynaptic cytomatrix protein {ECO:0000313|Ensembl:ENSCHIP00000014807.1};
GN Name=BSN {ECO:0000313|Ensembl:ENSCHIP00000014807.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000014807.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000014807.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000014807.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Presynaptic active zone
CC {ECO:0000256|ARBA:ARBA00034101}.
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DR EMBL; LWLT01000024; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSCHIT00000022606.1; ENSCHIP00000014807.1; ENSCHIG00000015658.1.
DR GeneTree; ENSGT00620000087961; -.
DR OMA; AHYYSDS; -.
DR Proteomes; UP000291000; Chromosome 22.
DR Bgee; ENSCHIG00000015658; Expressed in prefrontal cortex and 2 other cell types or tissues.
DR GO; GO:0042995; C:cell projection; IEA:UniProtKB-KW.
DR GO; GO:0048786; C:presynaptic active zone; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15773; FYVE1_BSN; 1.
DR CDD; cd15772; FYVE2_BSN_PCLO; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR030627; Bsn_FYVE_dom.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR008899; Znf_piccolo.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR14113; PICCOLO/BASSOON; 1.
DR PANTHER; PTHR14113:SF1; PROTEIN BASSOON; 1.
DR Pfam; PF05715; zf-piccolo; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
PE 4: Predicted;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 143..200
FT /note="Zinc finger piccolo-type"
FT /evidence="ECO:0000259|Pfam:PF05715"
FT DOMAIN 432..489
FT /note="Zinc finger piccolo-type"
FT /evidence="ECO:0000259|Pfam:PF05715"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 49..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 204..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 338..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 494..887
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 905..1213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1263..1334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1351..1509
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1529..1579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1875..1931
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2072..2123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2227..2326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2416..2453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2470..2618
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2771..2865
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2995..3111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3128..3185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3201..3361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3381..3515
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3531..3860
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2896..2933
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 65..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..221
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 530..544
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 584..598
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 639..668
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 754..786
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 805..820
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 916..944
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 945..970
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 971..989
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1016..1057
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1072..1086
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1115..1145
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1271..1299
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1362..1392
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1418..1449
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1485..1509
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1529..1558
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1559..1576
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2310..2326
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2502..2522
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2537..2567
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2598..2618
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2783..2810
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3008..3022
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3042..3059
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3128..3150
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3170..3185
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3201..3217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3245..3267
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3346..3361
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3417..3437
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3473..3487
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3498..3515
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3534..3559
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3571..3599
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3613..3640
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3649..3675
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3709..3723
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3724..3768
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3793..3814
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3815..3829
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3885 AA; 412931 MW; 137575EDB8EC6EAB CRC64;
PGSSAGKESA CNAGDPSSIP GSKRSPGEGK GYPLQYSWAS LVAQMVKNGV PRRLDPKEPL
GSQRAASPTP KQPSATTPGR ESPREPRAQG PEGQEADGPR RTLQVDSRTQ RSGRSPSVSP
DRGSTPTSPY SVPQIAPLPS STLCPICKTS DLTSTPSQPN FNTCTQCHNK VCNQCGFNPN
PHLTQVKEWL CLNCQMQRAL GMDMTTAPRS KSQQQLHSPG LSPAHSPAKQ PLGKPEQERA
RGPGGPQPGP RQAETARATS VPGPAPAAAP PEVGKVSPQP SLPIKPSTAE PRPPAGEAPA
KSATAAPSGP GAAEPTQEGL TGKLFGLGAS LLTQASTLMS AQPEVDSQGQ PAPSKGPPKI
VFSDASKEAG PRPPGSGPGP GPATGAKTEP GSGPRAQART GGTTSPKHGR TEHQAASKAA
AKPKTTPKER ATCPLCQAEL NVGSKGPANY NTCTTCKLQV CNLCGFNPTP HLVEKTEWLC
LNCQTKRLLE GSLGEPTPLP LPTSQQPPAG APHHTAGTAP PKQKGPQGLS QPSGPPPAKA
TPLPTKASPL PTKASPHAKP ARASEPSRTP SSAQEKKTGV PAKAEPVPKP PPETTLPPGT
PKAKAGVRRT EPTTPITKAV PEAPKGGETE EPGGKPYSQD LSRSPQSLSD TGYSSDGISS
SQSEITGIVR QEMEHLDSAG VTGPRPPSPS ELHKVGSSMR PSLEAQGPAP SGERSRPPSG
SAEEQKRRPR SLSIMPEAFN SDEELEEILE EEEDSTEWGR RGEQQDAAES SDDFGSQLRH
DYVEDSSEGG LSPLPPQPPA RAADLTDEEF MRRQILEMSA EEDNLEEDEA APAGPGLAKH
ASQKGGPQPR PESSQEPGRR LPHNATTGYE ELLSEGGPAE DVDGTAGALQ GGLRRFKTIE
LNSTGSYSHE LDMGPGPDPS LDREPELEME SLTGSPEDRS RGEHSSTLPA STPSYTSGTS
PTSLSSLEED SDSSPSRRQR LEEAKQQRKA RHRSHGPLLP TIEDSSEEEE LREEEELLRE
QEKMREVEQQ RIRSTARKTR RDKEELRAQR RRERSKTPPS NLSPIEDASP TEELRQAAEM
EELHRSSCSE YSPSPSLDSE AEAPEGAPSR LYKSGSEYNL PTFMSLYSPT ETPLGSATTP
SSGRPLKSAE EAYEEMMRKA ELLQRQQGQA AGGRGPHSGP PQPTAPRAQG SFEYQDSPDR
DYGGVAQPAA EGTPAGLGAA VYQEILQTSQ SIARMHQASS RDLAFAEDKK KEKQFLDAES
AYMDPMKQNG GPLTPGTSPT QLAAPVSFAT SSTSDSSGGR VIPDVRVTQH FAKEPQDPVK
LHSTPASPSS TSKEVGIGFA QGLGASASMA VTPGYMAPTS PAASERSPSP SFTGHGYGQS
PATANYGSQT EELPQAPRGP AVSGRAAREK PLGVSEGESG PPQTSRGYPY FVSSSPPLSP
SSPSESPTFS PGKLGPRATA EFSTQTPSPT PASDTPRSPG APAPTPTVAQ GTQTPHRPST
PRLVWQQPSQ DAPFMVITLA SDASSQTKMV HASASTSPVC SPVDTQPTTH SYSQTTPPSG
SQPPEPPGPP GFPRAPSAGA DGPLAVYGWG ALPAENISLC RISSVPGTSR VEPGPRPPGS
AVVDLRTAIK PTPIILTDQG MDLTSLAVEA RKYGLALDPI PGRQSTAVQP LVINLNAQEQ
THAFLSTATT VSITMASSVL MAQQKQPVVY GDPFQSRLDF GQGAGSPVCL AQVKQVEQAV
QTAPYRGGPR GRPRETKFAR YNLSNQVAPL ARRDVLITQV GPAQSVGLKS GPVPEPGTEP
HRAAPTELRS HALPGARKPH TVVVQVGEGA AGTVSTLLPE EPAGALDLTG MRPESQLACC
DMVYKFPFGS SCTGSFRTAP SAPERSVAEV APHGQSSGPF YSPRDPEPPE PPTYRAQVIG
GPGPHEEQRP YPQGLPGRLY SSMSDTNLAE AGLNYHAHRF GQLFQGPGRD SAMDLSSLKH
SYSLGFADGR YLGQGLQYGS FTDLRHPTDL LTHPLPMRRY SSVSNIYSDH RYGPRGDAAG
FQEASLAQYS ATTAREISRM CAALNSMDQY GGRHGSGGGG PDLMQYQPQP GLSAPQGLAP
LRPGLLGNPT FPEGQGSPGN LAQYRPTAGQ AAAVRQLLPS TATVRAADGM IYSTINTPIA
ATLPITTQPA SVLRPMVRGG MYRPYPPGGV AAVPLASLTR MPVIAPRIPL GPTGLYRYPV
PSRFPTPASV PPTEGPVYLG KPAAAKAPGT GGPSRPELPA GAAREEPLST APPAAAKETG
AAPALGAGQK PLGEATPGGG GGALGRPGLE KEDALPEERQ RKQQEQLLQL ERERVELEKL
RQLRLQEELE RERVELQRHR EEEQLLVQRE LQELQTLKHH VLQQQQEERQ AQFALQREQL
AQQRLQLEQI QQLQQQLQQQ LEEQKQRQKP PFPMACEAPG RGPPPAVPEL AQNGQYWPPL
THAAFIAVPE GSGQPREPML HRGLPSSASD MSLQTEEPWE GGRSGGLKKR HSMPRLRDVC
EPESAPEPCG VRRIADSSVQ TDEEDGEGRY LLTRRRRARR SADCSVQTDD EDSAEWEQPV
RRRRSRLSRH SDSGSDSKHD ATASSSAAAP TTRATSSVGI QTISDCSVQT EPDQLSRVSP
AIHITAVTDP KVEIVRYISA PEKTGRGESL ACQTEPEGQA QGVAGPQLMG PTAISPYLPG
IQIVTPGPLG RFEKKKPDPL EIGYQAHLPP ESLSQLVSRQ PPKSPQVLYS PVSPLSPHRL
LDTSFASSER LNKAHVSPQK HFTADSAFRQ QTLPRPMKTL QRSLSDPKPL SPTAEESAKE
RFPLYQHQGG LGSQVSAPPP NGLVRKVKRT LPSPPPEEAH LPLAGQAAPP QLYAASLLQR
GLVGPTAVPA TKASLLRELD RDLRLVEHES TKLRKKQAEL DEEEKEIDAK LKYLELGITQ
RKESLAKDRS GRDYPPLRGL SEHRDYLSDS ELNQLRLQGC ATAAGQYAEI PVTAAAAAPA
TPSGSAAFQP PRFPPPVPLY PAGSAGPTQN GFAAHQAPTY PGPSTYPSPA LPPSASYPAE
PGLPSQQAFR PPGHYAAQTP LPTTQTTLFP APADSRAPHQ KPRQTSLADL EQKVSTNYEV
IASPVVAMSS APSETSYSGP GPTASSSYEQ GKVPELPRAS DRGGVSLSPA PIYSSDSHYT
SLEQTVPRNY VMIDDISELT KDSASTAPES QRLEPLGPSS SGRPAKEPGE PGILEGSALP
CCYTRGEEES EEDSYEPRGK SGHHRGVESN GRPASTHYYS DSDYRHGTRA DKYSPGPAGP
KHPSKSLAPA AVPSKRSKHR KQGMEQKISK FSPIEEAKDV ESDLASYPSS AVSSSLASRG
RKFQDEITYG LKKNVYEQQR YYGVSSRDPA EEDDRVYGGS SRSRGAPAYS GEKLSSHDFG
GRAKGYERER EAVERLQKAG PKPSSLSMAH GRPRPPMRSQ ASEEESPVSP LGRPRPAGGP
LPPGDTCPPF CSSHSMPDVQ EHVKEGPRSH SYKRDEGYIL DDSHCVVSDS EAYHLGQEET
DWFDKPRDAR SDRFRHHGGH AVSSSSQKRG PARHSYHDYD EPPEEGLWPH DEGGPGRHAS
AKEHRHHGDH GRHSGRHASE EPSRRAAKPH VRDVGRHEAR PHPQPSPAQA VQKKGQPGYP
SSAEYSQPSR AQSAYHHSSE SKKGSRQAHP GPVALQPKLE SQPQPQGRQA APGPQPSQPP
PSRQMPSATA SRQPQTQPQP QQGLGLQPPQ QAPSQARLQQ QGQPAARGPA SAASQPAGKP
QAGPPTATGP QPSGPPRAEQ ANSSKGTAKA PQQGRPPQAQ PPPGPGPAGV KAGAKPGGTP
GAPAGQPGAE GESVLSKILP GGAAEQAGKL TEAVSAFGKK FSSFW
//
