ID A0A452EUB2_CAPHI Unreviewed; 948 AA.
AC A0A452EUB2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Myocardin related transcription factor A {ECO:0000313|Ensembl:ENSCHIP00000015511.1};
GN Name=MRTFA {ECO:0000313|Ensembl:ENSCHIP00000015511.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000015511.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000015511.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000015511.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; LWLT01000005; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A452EUB2; -.
DR STRING; 9925.ENSCHIP00000015511; -.
DR Ensembl; ENSCHIT00000023314.1; ENSCHIP00000015511.1; ENSCHIG00000016119.1.
DR GeneTree; ENSGT00950000182979; -.
DR OMA; SQPPCQL; -.
DR Proteomes; UP000291000; Chromosome 5.
DR Bgee; ENSCHIG00000016119; Expressed in longissimus thoracis muscle and 17 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:UniProt.
DR Gene3D; 6.10.140.2040; -; 1.
DR Gene3D; 6.10.150.10; -; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR InterPro; IPR043451; Myocardin-like.
DR InterPro; IPR004018; RPEL_repeat.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR PANTHER; PTHR22793:SF6; MYOCARDIN-RELATED TRANSCRIPTION FACTOR A; 1.
DR PANTHER; PTHR22793; MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED; 1.
DR Pfam; PF02755; RPEL; 3.
DR Pfam; PF02037; SAP; 1.
DR SMART; SM00707; RPEL; 3.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS51073; RPEL; 3.
DR PROSITE; PS50800; SAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT REPEAT 12..37
FT /note="RPEL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT REPEAT 49..74
FT /note="RPEL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT REPEAT 93..118
FT /note="RPEL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT DOMAIN 370..404
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 135..278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 311..368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 469..496
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 604..634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 654..679
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 697..833
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 546..584
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 135..165
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..188
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 208..236
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..362
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 697..712
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 713..738
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 756..774
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 948 AA; 100613 MW; 3F2AFD44C9017058 CRC64;
EDPLEKEMAT HSMLQLKLQQ RRTREELVSQ GIMPRKYSPA SRPLMETEDY LKRKIRSRPE
RSELVRMHIL EETSAEPSLQ AKQLKLKRAR LADDLNEKIA QRPGPMELVE KNILPVESSL
KEAIIVGQVN YPKVADSSSF DEDSSDALSP EQPASHESQG SVPSPLEARV SEPPPSATSV
SPAQVVSQLP VGPESGETLF LAEQPPLPPS LTNGTAVPTA KPLPTLIKQS QPKSAGEKSQ
RSKKAKELKP KVKKLKYHQY IPPDQKQDKG APPMDSSYAK ILQQQQLFLQ LQILNQQQQQ
QQQQHYNYQT ILPAPPKPAG EAGGSAGGPQ SRSLSTTSSS AGSGAPGPSG LVRQNSASLT
GKPGALPANL DDMKVAELKQ ELKLRSLPVS GTKTDLIERL RAYQEQVTPA SPGAPKAPTT
SLLPKAGEVV VAFPTARLST GPALVAAGLA PAEVVVATVT SNGVVKFGST GSTPPVSPTP
SERSLLSTGD ENSTPGDSFG EMVTSPVTQL TLQASPLQVL VKEEGPRPGA CCRSPGARAE
LEGRDKDQML QEKDKQIEEL TRMLRQKQQL VEWLRLQLEQ EKRAQQPPAP ALVTLGPAVK
QESGFTSCQL SRRPPGPELP FSPGLAAPAA PHTDTSALAP PVVVVKQEAV LPEPEPAPAP
QLLLGPQGPS LVKGVTPPPL LTDSAGTHLV LTVTKKNTDS PGLASGSPQQ PLSQPESPAP
GPPGRMDLEP PPQPLFGTPA SQPKKEPPGY EEAVSQQPRP QENGSSSQQM DDLFDILIQS
GEISADFKEP GKEKAPPTAA CGSPLAAQPS PAAELPQAAP PPSGSPALPG RLEDFLESST
GLPLLTGGHE GPEPLSLIDD LHSQMLSSSA ILDHPPSPMD TSELHFAPEP SGVGLDLADG
HLDSMDWLEL SSGGPVLSLA PLSTTAPSLF STDFLDGHDL QLHWDSCL
//
