ID   A0A452EZQ9_CAPHI        Unreviewed;       542 AA.
AC   A0A452EZQ9;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Terminal nucleotidyltransferase 4A {ECO:0000313|Ensembl:ENSCHIP00000017529.1};
GN   Name=TENT4A {ECO:0000313|Ensembl:ENSCHIP00000017529.1};
OS   Capra hircus (Goat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Caprinae; Capra.
OX   NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000017529.1, ECO:0000313|Proteomes:UP000291000};
RN   [1] {ECO:0000313|Ensembl:ENSCHIP00000017529.1, ECO:0000313|Proteomes:UP000291000}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA   Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA   Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA   Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA   Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT   "Polished mammalian reference genomes with single-molecule sequencing and
RT   chromosome conformation capture applied to the Capra hircus genome.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCHIP00000017529.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   EMBL; LWLT01000017; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_017921100.1; XM_018065611.1.
DR   AlphaFoldDB; A0A452EZQ9; -.
DR   Ensembl; ENSCHIT00000025339.1; ENSCHIP00000017529.1; ENSCHIG00000017328.1.
DR   GeneID; 102172200; -.
DR   CTD; 11044; -.
DR   GeneTree; ENSGT00940000157811; -.
DR   OrthoDB; 21395at2759; -.
DR   Proteomes; UP000291000; Chromosome 20.
DR   Bgee; ENSCHIG00000017328; Expressed in thymus and 16 other cell types or tissues.
DR   GO; GO:1990817; F:poly(A) RNA polymerase activity; IEA:InterPro.
DR   GO; GO:0016070; P:RNA metabolic process; IEA:UniProt.
DR   CDD; cd05402; NT_PAP_TUTase; 1.
DR   Gene3D; 1.10.1410.10; -; 1.
DR   Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR   InterPro; IPR043519; NT_sf.
DR   InterPro; IPR002058; PAP_assoc.
DR   InterPro; IPR002934; Polymerase_NTP_transf_dom.
DR   InterPro; IPR045862; Trf4-like.
DR   PANTHER; PTHR23092; POLY(A) RNA POLYMERASE; 1.
DR   PANTHER; PTHR23092:SF24; TERMINAL NUCLEOTIDYLTRANSFERASE 4A; 1.
DR   Pfam; PF01909; NTP_transf_2; 1.
DR   Pfam; PF03828; PAP_assoc; 1.
DR   SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR   SUPFAM; SSF81631; PAP/OAS1 substrate-binding domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000291000}.
FT   DOMAIN          15..123
FT                   /note="Polymerase nucleotidyl transferase"
FT                   /evidence="ECO:0000259|Pfam:PF01909"
FT   DOMAIN          178..237
FT                   /note="PAP-associated"
FT                   /evidence="ECO:0000259|Pfam:PF03828"
FT   REGION          323..382
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          485..542
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        348..382
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        485..507
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   542 AA;  59775 MW;  AA07362EC201A8EB CRC64;
     MSPCPEEAAM RREVVRRIET VVKDLWPTAD VQIFGSFSTG LYLPTSDIDL VVFGKWERPP
     LQLLEQALRK HNVAEPGSIK VLDKATVPII KLTDQETEVK VDISFNMETG VRAAEFIKNY
     MKKYSLLPYL ILVLKQFLLQ RDLNEVFTGG ISSYSLILMA ISFLQLHPRI DARRADENLG
     MLLVEFFELY GRNFNYLKTG IRIKEGGAYI AKEEIMKAMT SGYRPSMLCI EDPLLPGNDV
     GRSSYGAMQV KQVFDYAYIV LSHAVSPLAR SYPNRDSEST LGRIIKVTQE VIDYRTWIKE
     KWGGRVHGAP DPDNRVKTAE RMGVCEGDQP PRRDPEPPLG PRLTLSLPGP QLRSSGSSAS
     SVSSLSGSDI DSDTPPCTTP SVYQFSLQTP TPLLASLPTA LPMPSGKPQS TTSRTLVMTT
     NTQTRFTIPP PTLGVAPVPC RQAGIEAAPA LKAVHHVSSP AIPSASPNPL SSPHLYHKQH
     SGMKLSMKGS HSHGQGGSYT SVGTGSVRPP VGNRGHHQYN RTGWRRKKHT HTRDSLPVSL
     SR
//