ID A0A452EZR2_CAPHI Unreviewed; 517 AA.
AC A0A452EZR2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=BAR/IMD domain containing adaptor protein 2 like 2 {ECO:0000313|Ensembl:ENSCHIP00000017534.1};
GN Name=BAIAP2L2 {ECO:0000313|Ensembl:ENSCHIP00000017534.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000017534.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000017534.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000017534.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; LWLT01000005; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A452EZR2; -.
DR Ensembl; ENSCHIT00000025345.1; ENSCHIP00000017534.1; ENSCHIG00000017307.1.
DR GeneTree; ENSGT00940000153560; -.
DR Proteomes; UP000291000; Chromosome 5.
DR Bgee; ENSCHIG00000017307; Expressed in adult mammalian kidney and 10 other cell types or tissues.
DR GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR CDD; cd07644; I-BAR_IMD_BAIAP2L2; 1.
DR CDD; cd11914; SH3_BAIAP2L2; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR030126; Baiap2l2_I-BAR_dom.
DR InterPro; IPR013606; I-BAR_dom.
DR InterPro; IPR027681; IRSp53/IRTKS/Pinkbar.
DR InterPro; IPR035593; Pinkbar_SH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14206; BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2; 1.
DR PANTHER; PTHR14206:SF5; BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2-LIKE PROTEIN 2; 1.
DR Pfam; PF08397; IMD; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51338; IMD; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000291000};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..239
FT /note="IMD"
FT /evidence="ECO:0000259|PROSITE:PS51338"
FT DOMAIN 328..391
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 221..336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 391..517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..449
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 517 AA; 57862 MW; 23346F8164B78A0D CRC64;
MAPEMDQFYR STMAIYKSIL EQFNPALENL VYLGNNYLRA FHALSEAAEV YFNAIQKIGE
QALQSSTSQI LGEILVQMSD TQRHLNSDLE VVVQTFHGDL LQHIEKNTKL DMQFIRDSRQ
HYEMEYRHRA ASLEKSMSQL WRMERKRDKN AREMKESVNR LHAQMQAFVS ESQRAAELEE
KRRYRFLAEK HLLLSNTFLQ FFGRARGMLQ NRVLLWKEQS EASRSPSRAH SPGLLGPVLG
PPYPSGRLTP TRLDMPQRAL GEFGSPRSRH GSGSYGPEPA EARSASQLEP DHRRGRAGVP
GLPTHVARPS LYSSSTQRSR SNSFGERPGG GGVRALVSHS EGANHTLLRF SAGDVVEVLV
PEAQNGWLYG KLEGSSSSGW FPEAYVKPLE ELPMNPMNPR SPVNELPSRS YPLRGSHSLD
DLLDRPGNST ASSDYWDGQS RSRTPSRVPS RTPSPAPTPS SSSRRSSVGS MGVASDAKKL
ASWEQQPPEL FPRGTNPFAT VKLRPTVTND RSAPLIR
//
