ID A0A452F1C4_CAPHI Unreviewed; 1335 AA.
AC A0A452F1C4;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Apoptotic chromatin condensation inducer 1 {ECO:0000313|Ensembl:ENSCHIP00000017968.1};
GN Name=ACIN1 {ECO:0000313|Ensembl:ENSCHIP00000017968.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000017968.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000017968.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000017968.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; LWLT01000010; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_017910078.1; XM_018054589.1.
DR STRING; 9925.ENSCHIP00000017968; -.
DR Ensembl; ENSCHIT00000025782.1; ENSCHIP00000017968.1; ENSCHIG00000017602.1.
DR GeneID; 102182699; -.
DR CTD; 22985; -.
DR GeneTree; ENSGT00710000106790; -.
DR OMA; DYHKGIR; -.
DR OrthoDB; 1411884at2759; -.
DR Proteomes; UP000291000; Chromosome 10.
DR Bgee; ENSCHIG00000017602; Expressed in testis and 17 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd12432; RRM_ACINU; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR InterPro; IPR034257; Acinus_RRM.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR032552; RSB_motif.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR PANTHER; PTHR46589; APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; 1.
DR PANTHER; PTHR46589:SF1; APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; 1.
DR Pfam; PF16294; RSB_motif; 1.
DR Pfam; PF02037; SAP; 1.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS50800; SAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000291000}.
FT DOMAIN 72..106
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 159..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 476..858
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 886..946
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1091..1335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..175
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..234
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 242..269
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..292
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..380
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 502..527
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 538..558
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..605
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 606..638
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 639..671
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 687..703
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 705..732
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 750..776
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 794..813
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 886..909
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1091..1106
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1108..1124
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1126..1171
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1172..1186
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1187..1210
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1230..1316
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1335 AA; 150783 MW; 5E443E56E4D311EB CRC64;
MCRRKHPSTS GGTRGVLSGN RGVDYSSGRG QLGTFEGRWR KLPKMPEAVG TDPSTSRKMA
ELEEVTLDGK PLQALRVTDL KAALEQRGLA KSGQKSALVK RLKGALMLEN LQKHSTPHAA
FQPNSQIGEE MSQNSFIKQY LEKQQELLRQ RLEREAREAA ELEEASADSE DEMIHPEGVA
SLLPPDFQSS LERPELELSR HSPRKSTSIS EEKGESDEEK PRKGERRSSR VRQARAAKLS
ECSQAAEEEE DQETPSRNLR VRADRNLKTE EEEEEEEEEE EEEEEEEDDD EGQKSRDAPV
LKQFKEEGEE IPIVKVEEVT DERPQTIRSQ EQEGLERGGR VTRSQEEARR SHLARHQQEK
EMKTASLEEE EREIKFSKGL EEISKSPSPP RLTEDVAKAP VVLQPELTAS EEETPPPLLT
KEASSPPPNT QLQSEEEIEP MEGPAPPVLI QLSPPNADAE ARELLLSQHT VQLVGSLSPL
SGPADTKVES PVEKVPEESV LPLVQKSTQA ESSAQKGLET ESEKSTQPLP LKIEEFTLAK
GITEESLEQK EGRRASHVLL PSHRLKQSAD SSSSRSSSSS SSSSRSRSRS PDSSGSQSHS
PPRSKQRDAS GARAHANPRD RSKVGSRSTS ESRSRSRSRS RSASSNSRKS LSPGVSRDNS
TSYTETKDPS SGQEVAAPPL PQLQVLEPKE RTSTPSSIQV RRVSQPEPAE KHVTQRLQPD
RGSPKKCEAE EAEPPAATQP QTSETPASHL PESERTHHTV EEKEEVTMDT SENRAENEVP
EPPMPIADQV SNDDRPEGSA EDEEKKESLL PKSFKRKISV VSATKGVPAG NSDTEGGQPS
RKRRWGASTA ATQKKPSISI TTESLKSLIP DIKPLAGQEA VVDLHADDSR ISEDETERNG
DDGTHDKGLK ICRTVTQVVP AEGQENGQRE EEEEEKEPEA EAPVPPQVSV EVALPPPVEH
EVKKVTLGDT LTRRSISQQK SGVSITIDDP VRTAQVPSPP RGKISNIVHI SNLVRPFTLG
QLKELLGRTG TLVEEAFWID KIKSHCFVTY STVEEAVATR TALHGVKWPQ SNPKFLCADY
AEQDELDYHR GLLVDRPSET KTEEQGMPRP LHPPPPPPTQ PPQHPRAEQR EQERAVREQW
AEREREMERR ERTRSEREWD RDKVREGPRS RSRSRDRRRK ERAKSKEKKS EKKEKAQEEP
PAKLLDDLFR KTKAAPCIYW LPLTDSQIVQ KEAERAERAK EREKRRKEQE EEEQKEREKE
AERERTRQLE REKRREHSRE RDRERERDRE RDRGDRDRER DRERERGRER DRRDTKRHSR
SRSRSTPVRD RGGRR
//
