ID   A0A452F6R3_CAPHI        Unreviewed;       538 AA.
AC   A0A452F6R3;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Chromobox 4 {ECO:0000313|Ensembl:ENSCHIP00000019955.1};
GN   Name=CBX4 {ECO:0000313|Ensembl:ENSCHIP00000019955.1};
OS   Capra hircus (Goat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Caprinae; Capra.
OX   NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000019955.1, ECO:0000313|Proteomes:UP000291000};
RN   [1] {ECO:0000313|Ensembl:ENSCHIP00000019955.1, ECO:0000313|Proteomes:UP000291000}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA   Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA   Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA   Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA   Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT   "Polished mammalian reference genomes with single-molecule sequencing and
RT   chromosome conformation capture applied to the Capra hircus genome.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCHIP00000019955.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   EMBL; LWLT01000022; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A452F6R3; -.
DR   STRING; 9925.ENSCHIP00000019955; -.
DR   Ensembl; ENSCHIT00000027780.1; ENSCHIP00000019955.1; ENSCHIG00000018780.1.
DR   GeneTree; ENSGT00940000160081; -.
DR   OMA; CLSEPHG; -.
DR   Proteomes; UP000291000; Chromosome 19.
DR   Bgee; ENSCHIG00000018780; Expressed in cerebellum and 18 other cell types or tissues.
DR   GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR   GO; GO:0035102; C:PRC1 complex; IEA:Ensembl.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0019899; F:enzyme binding; IEA:Ensembl.
DR   GO; GO:0035064; F:methylated histone binding; IEA:Ensembl.
DR   GO; GO:0051219; F:phosphoprotein binding; IEA:Ensembl.
DR   GO; GO:0003727; F:single-stranded RNA binding; IEA:Ensembl.
DR   GO; GO:0032183; F:SUMO binding; IEA:Ensembl.
DR   GO; GO:0061665; F:SUMO ligase activity; IEA:Ensembl.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR   GO; GO:0016925; P:protein sumoylation; IEA:Ensembl.
DR   InterPro; IPR043531; CBX4.
DR   InterPro; IPR033773; CBX7_C.
DR   InterPro; IPR016197; Chromo-like_dom_sf.
DR   PANTHER; PTHR46727; E3 SUMO-PROTEIN LIGASE CBX4; 1.
DR   PANTHER; PTHR46727:SF1; E3 SUMO-PROTEIN LIGASE CBX4; 1.
DR   Pfam; PF17218; CBX7_C; 1.
DR   SUPFAM; SSF54160; Chromo domain-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000291000}.
FT   REGION          83..235
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          269..386
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          488..507
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        271..323
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        367..386
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   538 AA;  58798 MW;  88EBE78A5578D4E4 CRC64;
     MELPAVGEHV FAVESIEKKR IRKVGRYNTW EPEENILDPR LLIAFQNRER QEQLMGYRKR
     GPKPKPLVVQ VPTFARRSNV LTGLQDSSAD NRAKLELGGQ GKGQGHQYEL NSKKHHQYQP
     HSKERAGKPP PPGKSGKYYY QLNSKKHHPY QPDPKMYDLQ YQGGHKEAPS PTCPDLGSKS
     HPPDKWPHGG GAKGYLGAVK PLAGTAGAPG KGSEKGPPNG MTPAPKEAVT GNGIGGKMKI
     VKNKNKNGRI VIVMSKYMEN GMQAVKIKSG EAAEGEARSP SHKKRAAEER HPPADRTFKK
     AAGAEEKKAE TPSKRREEEA PGTGDPQSQE AGSRKLSPTK EAFGEQPLQL TTKPDLLAWD
     PARSTHPPSH HHHHHHHHHH HHAVDLNLSH ARKRCLSETH GEREPCKKRL TARSISTPTC
     LGGSPSAERP ADVPPAAALP QPEVILLDSD LDEPIDLRCV KTRSEAGEPP SALQVKPEAP
     ATAAVAAAPA TAAEKPPTEA HEEPEEPLSE FKPFFGNIII TDVTANCLTV TFKEYVTV
//