ID A0A452F9W6_CAPHI Unreviewed; 355 AA.
AC A0A452F9W6;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Carbohydrate sulfotransferase {ECO:0000256|RuleBase:RU364020};
DE EC=2.8.2.- {ECO:0000256|RuleBase:RU364020};
GN Name=CHST10 {ECO:0000313|Ensembl:ENSCHIP00000021063.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000021063.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000021063.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000021063.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU364020}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004323,
CC ECO:0000256|RuleBase:RU364020}. Membrane
CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 2 family.
CC {ECO:0000256|ARBA:ARBA00006339, ECO:0000256|RuleBase:RU364020}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LWLT01000009; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_017910411.1; XM_018054922.1.
DR AlphaFoldDB; A0A452F9W6; -.
DR STRING; 9925.ENSCHIP00000021063; -.
DR Ensembl; ENSCHIT00000028904.1; ENSCHIP00000021063.1; ENSCHIG00000019507.1.
DR GeneID; 102186023; -.
DR KEGG; chx:102186023; -.
DR CTD; 9486; -.
DR GeneTree; ENSGT00940000157128; -.
DR OMA; HWPEEFQ; -.
DR OrthoDB; 2907043at2759; -.
DR Proteomes; UP000291000; Chromosome 11.
DR Bgee; ENSCHIG00000019507; Expressed in frontal cortex and 17 other cell types or tissues.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:Ensembl.
DR GO; GO:0008209; P:androgen metabolic process; IEA:Ensembl.
DR GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR GO; GO:0008210; P:estrogen metabolic process; IEA:Ensembl.
DR GO; GO:0007612; P:learning; IEA:Ensembl.
DR GO; GO:0007616; P:long-term memory; IEA:Ensembl.
DR InterPro; IPR018011; Carb_sulfotrans_8-10.
DR InterPro; IPR005331; Sulfotransferase.
DR PANTHER; PTHR12137; CARBOHYDRATE SULFOTRANSFERASE; 1.
DR PANTHER; PTHR12137:SF2; CARBOHYDRATE SULFOTRANSFERASE 10; 1.
DR Pfam; PF03567; Sulfotransfer_2; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|RuleBase:RU364020};
KW Glycoprotein {ECO:0000256|RuleBase:RU364020};
KW Golgi apparatus {ECO:0000256|RuleBase:RU364020};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000};
KW Signal-anchor {ECO:0000256|RuleBase:RU364020};
KW Transferase {ECO:0000256|RuleBase:RU364020};
KW Transmembrane {ECO:0000256|RuleBase:RU364020}.
SQ SEQUENCE 355 AA; 41917 MW; B8C6ACA58A41081A CRC64;
MSDNMHHQWL LLAACFWVIF MFMVASKFIT LTFKDPDAYS AKQEFLFLTA VPDTGRSPGE
THLPEELKPT GRMLVEPLVY TQRLELMRNV CREDTLRNLS HTAISKFVLD RIFVCDKHKI
LFCQTPKVGN TQWKKVLIVL NGAFPSIEEI PENVVHDHEK NGLPRLSSFS EAEIQKRLKT
YFKFFIVRDP FERLISAFKD KFVHNPRFEP WYRHEIAPGI IRKYRRNRTE TRGIQFEDFV
RYLGDPNHRW LDLQFGDHII HWVTYVELCA PCEITYSIVG HHETLEDDAP YILREAGIDH
LVSYPTIPLG ITAYNRTKVE HYFLGISKRD IRRLYARFEG DFKLFGYQKP EFLLN
//
