ID A0A452FBJ4_CAPHI Unreviewed; 361 AA.
AC A0A452FBJ4;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=IF rod domain-containing protein {ECO:0000259|PROSITE:PS51842};
GN Name=LOC102179515 {ECO:0000313|Ensembl:ENSCHIP00000021678.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000021678.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000021678.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000021678.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR EMBL; LWLT01000022; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A452FBJ4; -.
DR Ensembl; ENSCHIT00000029531.1; ENSCHIP00000021678.1; ENSCHIG00000019803.1.
DR GeneTree; ENSGT00940000154403; -.
DR Proteomes; UP000291000; Chromosome 19.
DR Bgee; ENSCHIG00000019803; Expressed in rumen and 14 other cell types or tissues.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR PANTHER; PTHR23239:SF121; KERATIN, TYPE I CYTOSKELETAL 13; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR SUPFAM; SSF46579; Prefoldin; 1.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685}; Keratin {ECO:0000256|ARBA:ARBA00022744};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000}.
FT DOMAIN 50..361
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT COILED 54..88
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 147..199
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 260..347
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 361 AA; 40438 MW; D7D3C53E2E2FF07A CRC64;
WAHKDGYGGG FGGSFGGGFG GGFGGGFGGG FGGGFGDFGG GDGGLLSGNE KITMQNLNDR
LASYLEKVRA LEEANADLEV KIRDWHLKQT PTSPERDYSP YFKTIDELRE KILAATIDNN
RIILEIDNAR LAADDFRLKY ENELTLRQSV EADINGLRRV LDELTLTKTD LEMQIESLNE
ELAYLKKNHE EEMKEFSNQM AGQVNVEMDA TPGIDLTRVL AEMREQYEAM AEKNRRDAEA
WFHSKSAELN KEVSSSTAMI QTSKTEITEL RRTLQGLEIE LQSQLSMKAG LESTLAETEC
RYALQLQQIQ GLISSIEAQL SELRSEMECQ NQEYKMLLDI KTRLEQEIAT YRSLLEGQDA
K
//
