ID A0A452FDJ2_CAPHI Unreviewed; 422 AA.
AC A0A452FDJ2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Beaded filament structural protein 2 {ECO:0000313|Ensembl:ENSCHIP00000022217.1};
GN Name=BFSP2 {ECO:0000313|Ensembl:ENSCHIP00000022217.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000022217.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000022217.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000022217.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LWLT01000001; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A452FDJ2; -.
DR STRING; 9925.ENSCHIP00000022217; -.
DR Ensembl; ENSCHIT00000030077.1; ENSCHIP00000022217.1; ENSCHIG00000020270.1.
DR GeneTree; ENSGT00940000159820; -.
DR OMA; ETIRIQW; -.
DR Proteomes; UP000291000; Chromosome 1.
DR Bgee; ENSCHIG00000020270; Expressed in thymus and 11 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005212; F:structural constituent of eye lens; IEA:Ensembl.
DR GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR GO; GO:0045109; P:intermediate filament organization; IEA:Ensembl.
DR GO; GO:0070307; P:lens fiber cell development; IEA:Ensembl.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR PANTHER; PTHR23239:SF32; PHAKININ; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754};
KW Keratin {ECO:0000256|ARBA:ARBA00022744};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000}.
FT DOMAIN 104..416
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 199..240
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 314..391
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 422 AA; 46631 MW; 639AE23DA02BBBB6 CRC64;
MSTRRVVVDA PAGASSSMPL QRHKAPFRAA PSPSSLDGLP ASRTIAVGGL VRTPRVYVGM
TPSGPTGGLG ARVTRRALGI SSVFLQGLRS SGLATAPAPS LERDLGAVED LGGCLVEYMA
KVHALEKVSQ ELEAQLRMHL ESKATRSENW GALRASWASS CQQVGEAVLE NARLMLQTEN
IQAGADDFKE RYENEQPFRK AAEEEINSLY KVIDEANSSK MDLESQIESL KGELGFLSRS
YEEDVKMLYK QLAGSELEQL NVPIGTGLDD ILETIRIHWE RDVEKNRVQA GALLQAKQQA
ELARRAQTQE EKLAAALRVE LHNTSCQIQS LQAETESLRA LKRGLENTLH DAKHWHDIEL
QNLGAVVSRL EAELREMRAE AEQQLQAREH LLSHKCQLQR DVASYHALLD REESRCVSAQ
LC
//
