ID A0A452FFD7_CAPHI Unreviewed; 1236 AA.
AC A0A452FFD7;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Sushi domain-containing protein {ECO:0000259|PROSITE:PS50923};
GN Name=CFH {ECO:0000313|Ensembl:ENSCHIP00000023078.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000023078.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000023078.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000023078.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR EMBL; LWLT01000016; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A452FFD7; -.
DR Ensembl; ENSCHIT00000030938.1; ENSCHIP00000023078.1; ENSCHIG00000020774.1.
DR GeneTree; ENSGT00940000154386; -.
DR Proteomes; UP000291000; Chromosome 16.
DR Bgee; ENSCHIG00000020774; Expressed in liver and 17 other cell types or tissues.
DR CDD; cd00033; CCP; 16.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 20.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR45785:SF7; COMPLEMENT FACTOR H; 1.
DR PANTHER; PTHR45785; COMPLEMENT FACTOR H-RELATED; 1.
DR Pfam; PF00084; Sushi; 18.
DR SMART; SM00032; CCP; 19.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 18.
DR PROSITE; PS50923; SUSHI; 16.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Reference proteome {ECO:0000313|Proteomes:UP000291000};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302}.
FT DOMAIN 19..82
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 83..143
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 144..207
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 208..264
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 265..322
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 385..442
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 444..505
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 565..623
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 627..685
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 688..745
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 809..866
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 868..936
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 937..994
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 995..1053
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1054..1111
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1114..1172
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DISULFID 114..141
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 178..205
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 629..672
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 997..1040
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1116..1159
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 1236 AA; 139902 MW; C54A358856C7127E CRC64;
MVFPVVMDGC ESWTVKKAEY CKEPPPRKET EILSGSWTEQ TYREGTQATY KCSPGYRTLG
SIVMVCKGGK WVSLYPSRIC RKKPCAHPGD TPFGSFHLAE GTQFEYGAKV VYTCDEGYQM
LGEMNFRECD TNGWTNDIPI CEVVKCFPVT EPENGKIFSG ALEPDQEYTY GQVVQFECNS
GYMLNGPKQI HCSAGGVWSA ETPKCVEIFC KPPVILNGHA VLPKATYKAN ERVQYRCAAG
FEYGQRGDTI CTKSGWIPAP ACIEIICDPP RIPNGVYRPE LSKYRGQDKI TYKCKKGFIP
EIRGTEATCT RDGWAPAPRC AWKPCDYPVI KHGWLYYSYR GYFPAYVNQQ FVYSCDRYFV
PPSQRSWDYL TCTAQGWSPE EPCLRQCIFN YLENGYNPHR EEKYLQGKTV KVHCYEGYSL
QNDQNTMTCT ESGWSPPPRC IRVKTCSKSE IRIENGFLSE STFTYPLNKQ TEYKCKPGYV
TADGKTSGLI TCLQDGWSAQ PVCIKSCDKP VFEKARVKSD GTWFRLNDTL DYECFDGYET
REGRTTDSIV CGQDGWSDKA ACYERECSIP QMDTYLNAYP RKDTFKVGDV LKFSCSQGRI
MVGADSVQCY HFGWSPRLPA CKVRKVKSCA PPPQLLNGKG KEMHKEEYAH NEVVEYACNP
RFLMKGSHKI QCVDGRWTAL PVCIEEERTC GDIPDLDHGD IKPSVPPYHH GDSVEFSCRE
AFTMIGPRFI TCISGEWTQP PQCIATDELK KCKGSTLFPP EGKPAHTIEY DHNTNKSYQC
RGKSEQKHSI CINGEWDPKV DCKEEAQIQT CPPPPQIPNA RGMTTTVKYQ DGEKISILCK
ENYLIQDAEE IVCKDGRWQS IPRCIEKIGC SQPPQIDHGT VNSSSSAEER REIREQRLYA
HGTKLSYTCE EGFEIPENNV IICHMGKWSS PPQCVGLPCG VPPYIENGVV SHKNDSYQYG
EEVTYDCDEG FGTDGPASIR CLGGQWSRPQ DCISTNCVNL PTFDDAVLID QEKDSYKSGE
QVAFKCRSYY QLDGSNTIQC IKSKWIGRPA CRDVSCVNPP QVENAIVQNQ KSRYQSGERA
HYECIGNYDL FGETDVVCLN GTWTKPPQCK DSKGKCGPPP PIDNGDITSL LQSVYPPGMI
VEYRCQAYYE LQGNRNVVCR NGEWSEPPKC LEACVISEET MRKHHIQLKW KHDKKLYSKT
EDTIEFTCRY GYRPRTALHT FRTTCREGKV VYPQCG
//
