ID   A0A452FFL5_CAPHI        Unreviewed;       413 AA.
AC   A0A452FFL5;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Speckle type BTB/POZ protein like {ECO:0000313|Ensembl:ENSCHIP00000023229.1};
GN   Name=SPOPL {ECO:0000313|Ensembl:ENSCHIP00000023229.1};
OS   Capra hircus (Goat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Caprinae; Capra.
OX   NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000023229.1, ECO:0000313|Proteomes:UP000291000};
RN   [1] {ECO:0000313|Ensembl:ENSCHIP00000023229.1, ECO:0000313|Proteomes:UP000291000}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA   Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA   Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA   Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA   Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT   "Polished mammalian reference genomes with single-molecule sequencing and
RT   chromosome conformation capture applied to the Capra hircus genome.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCHIP00000023229.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the Tdpoz family.
CC       {ECO:0000256|ARBA:ARBA00010846}.
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DR   EMBL; LWLT01000002; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_017917904.1; XM_018062415.1.
DR   AlphaFoldDB; A0A452FFL5; -.
DR   SMR; A0A452FFL5; -.
DR   STRING; 9925.ENSCHIP00000023229; -.
DR   Ensembl; ENSCHIT00000031089.1; ENSCHIP00000023229.1; ENSCHIG00000020853.1.
DR   GeneID; 102168587; -.
DR   KEGG; chx:102168587; -.
DR   CTD; 339745; -.
DR   GeneTree; ENSGT00940000155953; -.
DR   OrthoDB; 5473088at2759; -.
DR   Proteomes; UP000291000; Chromosome 2.
DR   Bgee; ENSCHIG00000020853; Expressed in longissimus thoracis muscle and 17 other cell types or tissues.
DR   GO; GO:0031463; C:Cul3-RING ubiquitin ligase complex; IEA:Ensembl.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   CDD; cd18519; BACK_SPOPL; 1.
DR   CDD; cd18343; BTB_POZ_SPOPL; 1.
DR   Gene3D; 6.10.250.3030; -; 1.
DR   Gene3D; 6.20.250.50; -; 1.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR002083; MATH/TRAF_dom.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   InterPro; IPR008974; TRAF-like.
DR   PANTHER; PTHR24413; SPECKLE-TYPE POZ PROTEIN; 1.
DR   PANTHER; PTHR24413:SF91; SPECKLE-TYPE POZ PROTEIN-LIKE; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF00917; MATH; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00061; MATH; 1.
DR   SUPFAM; SSF54695; POZ domain; 1.
DR   SUPFAM; SSF49599; TRAF domain-like; 1.
DR   PROSITE; PS50097; BTB; 1.
DR   PROSITE; PS50144; MATH; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000291000}.
FT   DOMAIN          52..182
FT                   /note="MATH"
FT                   /evidence="ECO:0000259|PROSITE:PS50144"
FT   DOMAIN          221..283
FT                   /note="BTB"
FT                   /evidence="ECO:0000259|PROSITE:PS50097"
SQ   SEQUENCE   413 AA;  47086 MW;  DA0F89F5D3FCBBA0 CRC64;
     MVKYSPVWDI AYILEDCNKV AMSREPTPPL SGDMSIGPIA ESWCYTQVKV VKFSYMWTIN
     NFSFCREEMG EVLKSSTFSS SPSDKMKWCL RVNPKGLDDE SKDYLSLYLL LVSCPKSEVR
     AKFKFSLLNA KREETKAMES QRAYRFVQGK DWGFKKFIRR DFLLDEANGL LPDDKLTLFC
     EVSVVQDSVN ISGHTNTNML KVPECRLAED LGNLWENTRF TDCSFFVRGQ EFKAHKSVLA
     ARSPVFNAMF EHEMEESKKN RVEINDVDPE VFKEMMRFIY TGKAPNLDKM ADNLLAAADK
     YALERLKVMC EEALCSNLSV ENVADTLVLA DLHSAEQLKA QAIDFINRCS VLRQLGCKDG
     KNWNSNQAAD IMETSGWKSM IHSHPHLVAE AFRALASAQC PQFGIPRKRL KQS
//