ID A0A452FGE2_CAPHI Unreviewed; 435 AA.
AC A0A452FGE2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Zinc finger protein 772 {ECO:0000313|Ensembl:ENSCHIP00000023351.1};
GN Name=ZNF772 {ECO:0000313|Ensembl:ENSCHIP00000023351.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000023351.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000023351.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000023351.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; LWLT01000020; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005693069.2; XM_005693012.3.
DR AlphaFoldDB; A0A452FGE2; -.
DR STRING; 9925.ENSCHIP00000023351; -.
DR Ensembl; ENSCHIT00000031211.1; ENSCHIP00000023351.1; ENSCHIG00000020967.1.
DR GeneID; 102176259; -.
DR GeneTree; ENSGT00940000154734; -.
DR OMA; THCAEVF; -.
DR OrthoDB; 5255944at2759; -.
DR Proteomes; UP000291000; Chromosome 18.
DR Bgee; ENSCHIG00000020967; Expressed in prefrontal cortex and 16 other cell types or tissues.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 9.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24381; ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR24381:SF304; ZINC FINGER PROTEIN 772; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 8.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 8.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 5.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 8.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 9.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 14..94
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 91..118
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 212..239
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 240..267
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 268..295
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 296..323
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 324..351
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 352..379
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 380..407
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 408..435
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 435 AA; 49740 MW; 39A78E03AED929D8 CRC64;
MAAAVLTDPA QGNVTFEDVF VSFSQEEWGL LDETQRLLYR EVMLENFALM ASLGCWHGME
EDEIRFEQSI SVNRVSKGMI PKMIPSSQKA HPCETCGPIL RDVLHMAEHQ ETRPGQKPYL
CVACGKQLWF SANFPLHNQY SGEKPCRRDV HRALLVSSCP VQSLKTPFTT REGCEDFPTS
SSIFQQHYPL SKWNPQSDTH CAEVFHSGQK HYECSECGKT FSRKDSLVQH QRVHTGERPY
KCSECGKTFS RKPILAQHQR IHTGEMPYEC GICGKVFNHS SNLIVHQRVH TGARPYKCSE
CGKAYSHKST LVQHESIHTG ERPYECSECG KYFGHKYRLI KHWSVHTGAR PYECIACGKF
FSQSSDLIAH QRVHNGEKPY VCSECGKAFS HKHVLMQHLR IHTGERPYKC SECGKAFRQR
ASLIRHWKVH AGERP
//
