ID A0A452FGT6_CAPHI Unreviewed; 593 AA.
AC A0A452FGT6;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=DDB1 and CUL4 associated factor 8 {ECO:0000313|Ensembl:ENSCHIP00000023486.1};
GN Name=DCAF8 {ECO:0000313|Ensembl:ENSCHIP00000023486.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000023486.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000023486.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000023486.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; LWLT01000004; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005677283.1; XM_005677226.3.
DR RefSeq; XP_005677285.1; XM_005677228.3.
DR RefSeq; XP_013831381.1; XM_013975927.2.
DR RefSeq; XP_017901861.1; XM_018046372.1.
DR RefSeq; XP_017901863.1; XM_018046374.1.
DR STRING; 9925.ENSCHIP00000023486; -.
DR Ensembl; ENSCHIT00000031346.1; ENSCHIP00000023486.1; ENSCHIG00000021038.1.
DR Ensembl; ENSCHIT00010007029.1; ENSCHIP00010005066.1; ENSCHIG00010003597.1.
DR GeneID; 102184678; -.
DR KEGG; chx:102184678; -.
DR CTD; 50717; -.
DR GeneTree; ENSGT00950000182900; -.
DR OMA; ATQCCKT; -.
DR OrthoDB; 66220at2759; -.
DR Proteomes; UP000291000; Chromosome 3.
DR Proteomes; UP000694566; Chromosome 3.
DR Bgee; ENSCHIG00000021038; Expressed in longissimus thoracis muscle and 17 other cell types or tissues.
DR GO; GO:0080008; C:Cul4-RING E3 ubiquitin ligase complex; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR045151; DCAF8.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR15574:SF57; DDB1- AND CUL4-ASSOCIATED FACTOR 8; 1.
DR PANTHER; PTHR15574; WD REPEAT DOMAIN-CONTAINING FAMILY; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000291000};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 185..217
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 554..593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..67
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..96
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..135
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 593 AA; 66329 MW; 360F79512665C23C CRC64;
MSSKGSSTDG RTDLANGSLS SSPEEMSGAE EGRETSSGIE VEASDLSLSL TGDDGGPNRT
STESRGTDTE SSGEDKDSDS MEDTGHYSVN DESQVHDRSE EEEEEEEEHP RRRVQRKRAN
RDQDSSDDER ALEDWVSSET SALPRPRWQA LPALRERELG SSARFVYEAC GARVFVQRFR
LQHGLEGHTG CVNTLHFNQR GTWLASGSDD LKVVVWDWVR RQPVLDFESG HKSNVFQAKF
LPNSGDSTLA MCARDGQVRV AELSATQCCK NTKRVAQHKG ASHKLALEPD SPCTFLSAGE
DAVVFTIDLR QDRPASKLVV TKEKEKKVGL YTIYVNPANT HQFAVGGRDQ FVRIYDQRKI
DENENNGVLK KFCPHHLVNS ESKANITCLV YSHDGTELLA SYNDEDIYLF NSSHSDGAQY
IKRYKGHRNN ATVKGVNFYG PKSEFVVSGS DCGHIFLWEK SSCQIIQFME GDKGGVVNCL
EPHPHLPVLA TSGLDHDVKI WAPTAETSTE LTGLKDVIKK NKRERDEDSL HHTDLFDSHM
LWFLMHHLRQ RRHHRRWREP GVGATDADSD ESPSSSDTSD EEEGPDRVQC MPS
//
