ID   A0A452FJP9_CAPHI        Unreviewed;       800 AA.
AC   A0A452FJP9;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=U3 small nucleolar RNA-associated protein 25 homolog {ECO:0000256|ARBA:ARBA00024421};
DE   AltName: Full=UTP25 small subunit processor component {ECO:0000256|ARBA:ARBA00032325};
GN   Name=UTP25 {ECO:0000313|Ensembl:ENSCHIP00000024671.1};
OS   Capra hircus (Goat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Caprinae; Capra.
OX   NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000024671.1, ECO:0000313|Proteomes:UP000291000};
RN   [1] {ECO:0000313|Ensembl:ENSCHIP00000024671.1, ECO:0000313|Proteomes:UP000291000}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA   Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA   Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA   Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA   Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT   "Polished mammalian reference genomes with single-molecule sequencing and
RT   chromosome conformation capture applied to the Capra hircus genome.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCHIP00000024671.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604}.
CC   -!- SIMILARITY: Belongs to the UTP25 family.
CC       {ECO:0000256|ARBA:ARBA00009223}.
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DR   EMBL; LWLT01000016; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A452FJP9; -.
DR   Ensembl; ENSCHIT00000032532.1; ENSCHIP00000024671.1; ENSCHIG00000021738.1.
DR   GeneTree; ENSGT00390000000709; -.
DR   Proteomes; UP000291000; Chromosome 16.
DR   Bgee; ENSCHIG00000021738; Expressed in uterus and 17 other cell types or tissues.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0034511; F:U3 snoRNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010678; UTP25.
DR   PANTHER; PTHR12933; ORF PROTEIN-RELATED; 1.
DR   PANTHER; PTHR12933:SF0; U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG; 1.
DR   Pfam; PF06862; UTP25; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000291000}.
FT   REGION          1..161
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..17
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        19..42
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        43..65
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        85..124
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        144..161
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   800 AA;  91191 MW;  6A3DBAAD8E48BCBA CRC64;
     MGKRGSRSQS QLLGSLTKKQ KKHLRDFGEE HPFYDRVSRK EAKPQTCQLS ESSDTSSSES
     EAESEPEQVS GYHRLLATLK NVSKEEEEEE EEEEEEEDSA TDETEMNLED GDSDISEEEE
     MAAESADMQG SVPSPADPEG KDGHGPPGTS EESPEEFTDA KHESLFSLET NFLEEESGGD
     SSPKASQDPF VQHVNTKLKE KEIQAVATNP RTTHQLKWPI LGQVVFSSKF QKLETFKPPK
     DIDLKSVHLQ KPLESTWIKT NSQFLSGPQK SSSPFTPLQK ELFLIMNSYR DLFYPERTAL
     KNGEEIRHVY CLHVINHVLK ANAQVLANNS RRRSQKLGVG DDDDFRDQGL TRPKVLIVVP
     FREAALRVVQ LFISLLEGDS KKKIIVSNKK RFNGEYGSDP EERPPNLKRP EDYEAVFVGN
     IDDHFRIGVA ILQRSIRLYA PFYSSDILIA SPLGLRTIIG GEGEKKRDFD FLSSVELLII
     DQADIYLMQN WEHVLHLMNH MNLLPLDSHG VDFSRVRMWS LNNWSKYYRQ TLLFGALQDA
     QINSVFNKYC VNVQGQVGSP LSLTFGKCRV LFGSRGRRGG LHLVSSGDSS PPDALSDPWQ
     VAVRNVPMTG SISQVLVQLP HVFQRMEAES LASVIDARFN FFVNKILPQY RDAVMSHTLI
     YVPSYFDFVR LRNYFKKEEL NFTHICEYTQ KSGVSRARHF FLQGEKQFLL LTERFHFYKR
     YTIKGIRNLI FYELPTYPHF YSEVCNMLRA TSSGEEAAWT CTVLYSKYDA QRLAAVVGVE
     RAAQMLQSKK NVHLFITGER
//