ID   A0A452FMF5_CAPHI        Unreviewed;       714 AA.
AC   A0A452FMF5;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=NCK interacting protein with SH3 domain {ECO:0000313|Ensembl:ENSCHIP00000025343.1};
GN   Name=NCKIPSD {ECO:0000313|Ensembl:ENSCHIP00000025343.1};
OS   Capra hircus (Goat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Caprinae; Capra.
OX   NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000025343.1, ECO:0000313|Proteomes:UP000291000};
RN   [1] {ECO:0000313|Ensembl:ENSCHIP00000025343.1, ECO:0000313|Proteomes:UP000291000}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA   Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA   Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA   Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA   Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT   "Polished mammalian reference genomes with single-molecule sequencing and
RT   chromosome conformation capture applied to the Capra hircus genome.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCHIP00000025343.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   EMBL; LWLT01000024; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A452FMF5; -.
DR   STRING; 9925.ENSCHIP00000025343; -.
DR   Ensembl; ENSCHIT00000033205.1; ENSCHIP00000025343.1; ENSCHIG00000022149.1.
DR   GeneTree; ENSGT00390000015725; -.
DR   OMA; TGFERQY; -.
DR   Proteomes; UP000291000; Chromosome 22.
DR   Bgee; ENSCHIG00000022149; Expressed in prefrontal cortex and 16 other cell types or tissues.
DR   GO; GO:0008180; C:COP9 signalosome; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   CDD; cd11849; SH3_SPIN90; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   InterPro; IPR030125; SPIN90/Ldb17.
DR   InterPro; IPR018556; SPIN90/Ldb17_LRD.
DR   InterPro; IPR035514; SPIN90_SH3.
DR   PANTHER; PTHR13357:SF1; NCK-INTERACTING PROTEIN WITH SH3 DOMAIN; 1.
DR   PANTHER; PTHR13357; SH3 ADAPTER PROTEIN SPIN90 NCK INTERACTING PROTEIN WITH SH3 DOMAIN; 1.
DR   Pfam; PF00018; SH3_1; 1.
DR   Pfam; PF09431; SPIN90_LRD; 1.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000291000};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          1..58
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REGION          101..124
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          149..274
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        191..229
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        254..270
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   714 AA;  78131 MW;  E535719C3E62423A CRC64;
     MYRALYAFRS AEPNALAFAA GETFLVLERS SAHWWLAARA RSGETGYVPP AYLRRLQGLE
     QDVLQAIDRA IEAVHNAAVR DGGKYSLEQR GVLQKLIHHR KETLSRRGPS APSPAAMTPS
     TSDHHLDAAA TRQPNGTCRA GFERQHSLPS SEYLGADGGL YQIPPQPRRA APTTPPPPVK
     RRDRDALIIS GSGGRNTTPS GGSSVSSGGS ISSTSLDTLY TGSSSSEPGP SCSPTPPPVP
     RRGMLTAVSQ AQPPPCKVPN PEPPTEEEAT APAPVPDELE ALRALNLGAT EEKAVAEPAV
     PRTIGAELME LVRRNTGLSH ELCRVAIGVV VGHIQASVPA SSPVMEQVLL SLVEGKDLST
     ALPSGQVCHD QQRLEVIFAD LARRKDDAQQ RSWALYEDEG VIRCYLEELL HILTDADPEV
     CKKMCKRNEF ESVLALVAYY QMEHRVSLRL LLLKCFGAMC SLDAAIISTL VSSVLPVELA
     RDMQTDTQDH QKLCYSALIL AMVFSMGEAV PYAHYEHLGT PFAQFLLSIV EDGLPLDTTE
     QLPDLCVNLL LALNLHLPAP DQNVIMAALS KHANVKIFSE KLLLLLNRGD DPVRIFKHEP
     QPPHSILKFL QDVFASPATA AIFYHTDMMA LIDITVRHIA DLSPGDKLRM EYLSLMHAVV
     RSTPYLQHRH RLADLQATLR RILTEEEASP QCQMDRMIVQ EMCKEFPVLG EAPS
//