ID A0A452FSN8_CAPHI Unreviewed; 1913 AA.
AC A0A452FSN8;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Microtubule crosslinking factor 1 {ECO:0000313|Ensembl:ENSCHIP00000027166.1};
GN Name=MTCL1 {ECO:0000313|Ensembl:ENSCHIP00000027166.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000027166.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000027166.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000027166.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; LWLT01000023; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 9925.ENSCHIP00000027166; -.
DR Ensembl; ENSCHIT00000035034.1; ENSCHIP00000027166.1; ENSCHIG00000023205.1.
DR GeneTree; ENSGT00950000182982; -.
DR OMA; DHANKNC; -.
DR Proteomes; UP000291000; Chromosome 24.
DR Bgee; ENSCHIG00000023205; Expressed in cerebellum and 16 other cell types or tissues.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0010506; P:regulation of autophagy; IEA:InterPro.
DR InterPro; IPR027882; DUF4482.
DR InterPro; IPR027881; SOGA.
DR PANTHER; PTHR15742:SF3; MICROTUBULE CROSS-LINKING FACTOR 1; 1.
DR PANTHER; PTHR15742; UNCHARACTERIZED; 1.
DR Pfam; PF14818; DUF4482; 1.
DR Pfam; PF11365; SOGA; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000}.
FT DOMAIN 1204..1327
FT /note="DUF4482"
FT /evidence="ECO:0000259|Pfam:PF14818"
FT REGION 1..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 570..589
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 626..646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 723..792
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1055..1096
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1254..1288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1376..1400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1615..1643
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1661..1710
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1731..1796
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1819..1913
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 333..403
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 432..480
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 798..825
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1214..1252
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 21..36
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..94
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..156
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..219
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 256..270
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 736..774
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1064..1078
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1695..1710
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1755..1769
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1876..1891
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1913 AA; 209625 MW; 9A08152CCFB0D5F2 CRC64;
METLNGPAGG GAQDAKPQPP GQHHRHHHHL HPLAERRRLH RAPSPARPFL KDLHGRPAAP
VQAAPSSGRA PAPAAPRSPS LAGKAPPSPG PPAAPGRLSR RSGGAPGAKD KPPPGAGARA
AGGAKAAPGP RRVARAAPAE PLPRVGKPPP GAEPPPAAAK GRRAKRASGA VPARAAGPRL
PAVAVPSVIL AVTSAAGSPA PGSRISHTDS SSDLSDCPSD PLSDEQRLLP AASSDAESGT
GSSDREPLRG APTTSPPTRG APPDSPEPSG LLAAPPAACL GGRNSPSGVP SASPGPGVVE
DVAGRAPPER TCPGTPREHG PDEQHRLVPA AEEEELLREM EELRSENDYL KDELDELRAE
MEEMRDSYLE EEVYQLQELR RELDRANKNC RILQYRLRKA EQKRLKVAET GQVDGELIRS
LEQDLKVAKD VSVRLHHELE TVEEKRAKAE DENETLRQQM IEVEISKQAL QNELERLKES
SLKRRGSREA YKEKKAFTQN GGAEHLGNCR STAKAQRKLP PRRKDDSADL RCQLQFAKEE
GSLMLRKMAK LGREKDRLEQ ELQRYRALYG DADSPLPTGE AGGPPSTREA ELKLRLRLVE
EEASILGRKI VELEVENRGL KAEMEDLRGR EPLPGGPTSP FGGDSLESSA ELRRHLQFVE
EEAELLRRSI SEIEDHNRQL THELSKFKFE PRPEPGWLAG GGAPLQDELQ AVRLPISELS
GEVLTLQPGP RAPSPRDSDA DSDTGRRSDD GEDGRVQPRR EGPIGGESDS EETFEKTSGF
GSGRPSEAGE CPAELLRARE DSERLASIRH EAERLERTVE RIITDTEAAL PAGEASPEAC
GQDTREEPQL LGTLNARMKA FRKELQAFLE QVERLGEGLS PLPQLTESSS FLSSVTSVSR
DSPVGNLGKE LGPDLQSKLR DQMEWQPGQE RGEERGHLHL RTARELHRRA DGDAGSCRPG
AQSCFSLEAE EERRCALRRR DREANGLALQ ASLHERAWGD ERHLMQQELR SLKQNIFLFY
VKLRWLLKHW RQGRQVEDDA EDFMESELPE TFPRLGELGV QGDTKADSPD RDDDGPGCGF
SLGEHSPQTG GHGLRLQPTD GGQLYRQVAE TQPLFCALKA LLEELRAELR EDARARQRLQ
QQYAGDKAAW DMEWAALTCR LEQLEAKNEK SLGDPGSCTD SKGAFRKERE VQQKLLADSH
RLVMDLRWQI HHSEKNWNRE KVELLDRLDR ERQEWGQQEK ELLWRIEQLQ KENSPQRGGS
FLCDQEEGDA RSCTHPGSPR APRPTGMWPC MDTDSNAFED RPLSKLKESD RCSARENLYL
DTLSLDDEPE EPPAHGPQRE FRNCFHEEED NHKGNLQRAV SVSSMSEFQR LMDGSPFLPE
KSLPPTCSKE DVTPPLSPDD LKYIEEFNSK SWDERPLDPW ADRTEVGRTR PEASTEPFSD
AAWYLTTSIT LTTDTVTNPE HCQKQPLRNL VCAEQAGGRG LHSPPAIRRL DGIVAGVGES
RVRGGPGDAK GSPSEHVLSR WPCALSRHPR DYTEGGLRPL DSTLSFSPLH SLEMPRNLSD
DMKEVAFSVR STVCSSPGEP LVKDTACQTN GSRTTGTQTV QTISVGLQTE ALRGSPHKCL
TPKAGGGATP ASSPSRGLRN RQVAPAIEKV QAKFERTCCS PKYGSPKLQR KPLPRVDQSS
SRASPGLAQK GCGESAWARS TTTRESPVHT AMNDGLSSLF SIIDHSPVVQ DPFQKGVRTA
SRSRSAEPRP ELGPGQDTSP SSRGRSPSPI GGGSETCREE GGEGTPLRQD LSAPPGYTLT
ENVARILHRK LLEHALKEER RQAAYSPTNT GSDNHMGETA VKAEPGSIEE LPCSALAPSL
EPCFSRPERP ANRRPPSRWA PHPPTASPAP SPGEPTSSEE LGDEEPPGEK PHV
//
