ID A0A452FYJ0_CAPHI Unreviewed; 845 AA.
AC A0A452FYJ0;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=A-kinase anchoring protein 1 {ECO:0000313|Ensembl:ENSCHIP00000029393.1};
GN Name=AKAP1 {ECO:0000313|Ensembl:ENSCHIP00000029393.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000029393.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000029393.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000029393.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; LWLT01000022; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_017919584.1; XM_018064095.1.
DR AlphaFoldDB; A0A452FYJ0; -.
DR STRING; 9925.ENSCHIP00000029393; -.
DR Ensembl; ENSCHIT00000037263.1; ENSCHIP00000029393.1; ENSCHIG00000024545.1.
DR GeneID; 102184753; -.
DR KEGG; chx:102184753; -.
DR CTD; 8165; -.
DR GeneTree; ENSGT00390000001360; -.
DR OMA; CLTNIYT; -.
DR OrthoDB; 4118571at2759; -.
DR Proteomes; UP000291000; Chromosome 19.
DR Bgee; ENSCHIG00000024545; Expressed in longissimus thoracis muscle and 16 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR GO; GO:0034237; F:protein kinase A regulatory subunit binding; IEA:Ensembl.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140374; P:antiviral innate immune response; IEA:Ensembl.
DR GO; GO:0006915; P:apoptotic process; IEA:Ensembl.
DR CDD; cd22395; KH-I_AKAP1; 1.
DR CDD; cd20407; Tudor_AKAP1; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 2.40.50.90; -; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR InterPro; IPR047368; KH-I_AKAP1.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR047367; Tudor_AKAP1.
DR PANTHER; PTHR22948:SF65; A-KINASE ANCHOR PROTEIN 1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR22948; TUDOR DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF00013; KH_1; 1.
DR Pfam; PF00567; TUDOR; 1.
DR SMART; SM00322; KH; 1.
DR SMART; SM00333; TUDOR; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
DR PROSITE; PS50304; TUDOR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 700..759
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT REGION 59..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 249..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 314..334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 377..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 504..523
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 441..461
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 845 AA; 89380 MW; B81C5E1A7E450B41 CRC64;
MTIQFRSLFP LALPGVLALL GWWWFFSRKK EPLDSHDRAA EAGAVALRAG PAAQEALTAE
DVRPGVASPP PETELCGSGR PSPEPPALLR AHPACRRSES SGSLPNPADM RLRPGARKEV
ELALAGDEAK AVPLECPLPA PKGLPFPHEA VEVCKREAVL GRPGGRGLQG QPAAPVEKPC
IGEKAWETGG AEGTGDAVLG ENVLEEGPAA WEPAPELELQ SGQAAGAGEK GPGCPLDEAV
AEAVPEETLA PRGQAGRAWD GAFPQEQGGE ETWDRSEKME QAAFQIISKV ILEATEEVLA
TTMGRIAGRV YQASAAQPQE PKEESCAPAS QKTPLGLEAS EPTLAEAEAP VSLGDTAVPS
AEPLAGDLPA PKTYVSCLSS PLSSPTKDRK PKNSAHHISL APCPPPAAPL RELLDKAGGP
GEEATRVPCV SDGGQAVPGG DSAVTSGQHS DSASNSGLED CCPETAPSPR GEAATPPLPE
STVPISNGVL KGELSDLGTE DGWTVDAEAD HSGGSDGNSM DSVDSCCGLR KPDGFQNAQA
GSNPKKVDLI IWEIEVPKHL VGRLIGKQGR YVSFLKQTSG AKIYISTLPY TQNIQVCHIE
GSQHHVDKAL NLIGKKFKEL NLTNIYAPPL PSLALPSLPM TSWLMLPDGV TVEVIVVNQV
NAGHLFVQQH THPTFHALRS LDQQMYLCYS QPGIPTLPTP VEITVICAAP GVDGAWWRAQ
VVAAYEDTNE VEIRYVDYGG YKRVKVDVLR QIRSDFVTLP FQGAEVLLDS VMPLSDDDHF
SPEADAAMSE MTGNTALLAQ VTSYSPTGLP LIQLWSVVGD EVVLINRSLV ERGLAQWVDS
CYSSL
//
