ID A0A452G415_CAPHI Unreviewed; 318 AA.
AC A0A452G415;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=DED domain-containing protein {ECO:0000259|PROSITE:PS50168};
GN Name=DEDD {ECO:0000313|Ensembl:ENSCHIP00000031284.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000031284.1, ECO:0000313|Proteomes:UP000291000};
RN [1] {ECO:0000313|Ensembl:ENSCHIP00000031284.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000031284.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
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DR EMBL; LWLT01000004; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_017901892.1; XM_018046403.1.
DR RefSeq; XP_017901893.1; XM_018046404.1.
DR RefSeq; XP_017901894.1; XM_018046405.1.
DR RefSeq; XP_017901895.1; XM_018046406.1.
DR AlphaFoldDB; A0A452G415; -.
DR STRING; 9925.ENSCHIP00000031284; -.
DR Ensembl; ENSCHIT00000039157.1; ENSCHIP00000031284.1; ENSCHIG00000025706.1.
DR GeneID; 102170568; -.
DR KEGG; chx:102170568; -.
DR CTD; 9191; -.
DR GeneTree; ENSGT00390000008714; -.
DR OMA; QAWPEEE; -.
DR OrthoDB; 3058503at2759; -.
DR Proteomes; UP000291000; Chromosome 3.
DR Bgee; ENSCHIG00000025706; Expressed in longissimus thoracis muscle and 18 other cell types or tissues.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006915; P:apoptotic process; IEA:InterPro.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR CDD; cd08790; DED_DEDD; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR001875; DED_dom.
DR InterPro; IPR038856; DEDD/DEDD2.
DR InterPro; IPR049341; TRADD-like_N.
DR PANTHER; PTHR15205; DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR15205:SF2; DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01335; DED; 1.
DR Pfam; PF20694; TRADD-like_N; 1.
DR SMART; SM00031; DED; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR PROSITE; PS50168; DED; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 25..103
FT /note="DED"
FT /evidence="ECO:0000259|PROSITE:PS50168"
FT REGION 160..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 318 AA; 36757 MW; 6AAC292FF28E067D CRC64;
MAGLKRRASQ AWPEEHGEQE HGLYSLHRMF DIVGTHLTHR DVRVLSFLFV DVIDDHERGL
IRNGRDFLLA LERQGRCDES NFRQVLQLLR IITRHDLLPY VTLKRRRAVC PDLVDKYLEE
TSVRYVTPRA LSDPEPRPPH PPKTVPPHYP VVCCPTSGPQ MCSKRPARGR ATLGSQRKRR
KSVTPDPKEK QTCDIRLRVR AEYCQHESAL QGNVFSNKQD PLERQFERFN QANTILKSRD
LGSIICDIKF SELTYLDAFW RDYINGSLLE ALKGVFITDS LKQAVGHEAI KLLVNVDEED
YELGRQKLLR NLMLQALP
//
