ID   A0A452G877_CAPHI        Unreviewed;       858 AA.
AC   A0A452G877;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Tetratricopeptide repeat domain 7A {ECO:0000313|Ensembl:ENSCHIP00000032738.1};
GN   Name=TTC7A {ECO:0000313|Ensembl:ENSCHIP00000032738.1};
OS   Capra hircus (Goat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Caprinae; Capra.
OX   NCBI_TaxID=9925 {ECO:0000313|Ensembl:ENSCHIP00000032738.1, ECO:0000313|Proteomes:UP000291000};
RN   [1] {ECO:0000313|Ensembl:ENSCHIP00000032738.1, ECO:0000313|Proteomes:UP000291000}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA   Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA   Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA   Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA   Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT   "Polished mammalian reference genomes with single-molecule sequencing and
RT   chromosome conformation capture applied to the Capra hircus genome.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCHIP00000032738.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   EMBL; LWLT01000009; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_005686630.2; XM_005686573.3.
DR   AlphaFoldDB; A0A452G877; -.
DR   STRING; 9925.ENSCHIP00000032738; -.
DR   Ensembl; ENSCHIT00000040614.1; ENSCHIP00000032738.1; ENSCHIG00000026586.1.
DR   GeneID; 102171884; -.
DR   KEGG; chx:102171884; -.
DR   CTD; 57217; -.
DR   GeneTree; ENSGT00940000158638; -.
DR   OMA; CRSECNW; -.
DR   OrthoDB; 25200at2759; -.
DR   Proteomes; UP000291000; Chromosome 11.
DR   Bgee; ENSCHIG00000026586; Expressed in fallopian tube and 18 other cell types or tissues.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0006879; P:intracellular iron ion homeostasis; IEA:Ensembl.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IEA:Ensembl.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR045819; TTC7_N.
DR   PANTHER; PTHR23083:SF475; TETRATRICOPEPTIDE REPEAT PROTEIN 7A; 1.
DR   PANTHER; PTHR23083; TETRATRICOPEPTIDE REPEAT PROTEIN, TPR; 1.
DR   Pfam; PF13432; TPR_16; 1.
DR   Pfam; PF13181; TPR_8; 1.
DR   Pfam; PF19440; TTC7_N; 1.
DR   SMART; SM00028; TPR; 6.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50005; TPR; 3.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000291000};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   DOMAIN          9..403
FT                   /note="Tetratricopeptide repeat protein 7 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19440"
FT   REPEAT          566..599
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          745..778
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          813..846
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   858 AA;  95847 MW;  C58C57E1F15C54C3 CRC64;
     MAAKGAYGSH LKMESELERC RAEGHWDRMP ELVRQMQALV MLGGGGGRRG SPSAGFTSLD
     TDDLGKLLLA EALLEQCLKG NHATIKDSIP LLEKNEPKMN EARNYLSSIL NHGKLPPQYL
     CEAMLILGKL HYVEGSYRDA ISMYARAGID DMSMENKPLY QMRLLAEAFV IKGLSLERLP
     NSIASRPRLT EREEEVITCF ERASWIAQVF LQELEKVTSN TTSRHLKGSH PVDYELTYFL
     EAALQSAYVT HLKKGNIVKG MRELREVLRT VETKATQNFK VMAAKHLAGV LLHSLSEECY
     WSPLSQPLPE FMSKEENSFI TQALRKPHLY EGDNLYCPKD NIEEALLLLL ISESMATRDV
     VLSRAPEQEE DRAVSLQNAA AIYDLLSITL GRRGQYVMLS ECLERAMKFA FGEFHLWYQV
     ALSMVACGKS SYAVSLLREC VKLRPSDPTV PLMAAKVCIG SLHWLEEAER FAMMVIHLGE
     GAGEFLSKGY LALGLTYSLQ ATDATLKSKQ DELHRKALQT LERAQQLAPS DPQVILYVSL
     QLALVRQISS AMEQLQEALK VCRDDANALH LLALLFSAQK HYQHALDVIN MAITEHPENF
     NLMFTKVKLE QILKGPEEAL VTCRQMLRLW QTLYSFSQLG GLEKDGSLGE GLTLKKQSGM
     HLTLPDAHDA DSGSRRASSI AASRLEEAMS ELTVPSSVLK QGPMQLWTTL EQIWLQAAEL
     FMEQQHLKEA GFCIQEAAGL FPTSHSVLYM RGRLAEMKGR LEEAKQLYSE ALTVNPDGVR
     IMHSLGLMLS RLGHKSLAQK VLRDAVERQS TCHEAWQGLG EVLQAQGQSE AAVDCFLTAL
     ELEASSPVLP FSIIPREL
//