ID A0A452GFP9_9SAUR Unreviewed; 1531 AA.
AC A0A452GFP9;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
OS Gopherus agassizii (Agassiz's desert tortoise).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Testudinidae; Gopherus.
OX NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000000330.1, ECO:0000313|Proteomes:UP000291020};
RN [1] {ECO:0000313|Proteomes:UP000291020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28562605;
RA Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT "The Agassiz's desert tortoise genome provides a resource for the
RT conservation of a threatened species.";
RL PLoS ONE 12:e0177708-e0177708(2017).
RN [2] {ECO:0000313|Ensembl:ENSGAGP00000000330.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the dispatched family.
CC {ECO:0000256|ARBA:ARBA00038046}.
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DR STRING; 38772.ENSGAGP00000000330; -.
DR Ensembl; ENSGAGT00000000373.1; ENSGAGP00000000330.1; ENSGAGG00000000279.1.
DR Proteomes; UP000291020; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR003392; Ptc/Disp.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR45951:SF4; PROTEIN DISPATCHED HOMOLOG 1; 1.
DR PANTHER; PTHR45951; PROTEIN DISPATCHED-RELATED; 1.
DR Pfam; PF02460; Patched; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000291020};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 188..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 499..518
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 524..545
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 597..621
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 633..654
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 719..737
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 985..1004
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1010..1032
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1039..1059
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1079..1096
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1108..1127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 524..658
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 1531 AA; 172454 MW; D224372CBE41E28D CRC64;
MAMNNGNSDF VVLSNGSILS SATSPSILSA TDGGIAAQHL PSKEAPRAKV SPNGCLQLNG
TIKPSFLPLD NQRTQQMLTH CCHPCPYHHP ISSHNKQQEC HSLAGSTAPS PMTSCCLQPH
TEYSASICQK HTPMYQATCC LQHSPSFCLH HQWPDHFQHQ SVQQHVASVR PARPFKLPKS
YAALIADWPV VVLGMCTVLI VVCALVGILV PDLPDFSDPL LGFEPRGTAI GQRLVTWNNM
VKNTGYKATL ANYPFKYADE QAKSHQDDRW SDDHYEREKR QADWNFHKDS FFCDIPSDRY
SRVVFTSTEG ENLWNLHAIK SMCSVDNLRI RSHSQFGDLC QRTTAASCCP SWTLGNYIAI
LNNRSSCQKI VERDVSHTLK LLRTCAKYYY NGTLGPDCWD VAAKRKDQLK CTNVPRKCTK
YNAVYQILHY LVDKDFLNPK TADYVLPALK YSMLFSPTEK GESMMNIYLD NFENWNSSDG
ITTITGIEFG IKHSLFQDYL LMDTVYPAIA IVIVLLVMCV YTKSMFITLM TMFAIISSLI
VSYFLYRVVF NFEFFPFMNL TALIILVGIG ADDAFVLCDV WNYTKFDKSH ADTSETVSIT
LQHAALSMFV TSFTTAAAFY ANYVSNITAI QCFGVYAGTA ILVNYVLMVT WLPAVVVLHE
RYLLNIFTCF KKPQQRVYSN KDCCTVLCQV CHKIIFAVSE ASRIFFEKVL PCIVIKFRYI
WLFWFLALTV GGAYIVCVNP KMKLPSLELS EFQVFRSSHP FERYDAEYKK LFMFERVHHG
EELHMPITVI WGVSPEDNGD PLNPKSKGKL KLDSSFNIAS PASQVWILHF CQKLRNQTFY
YQTEEQDFAS CFIETFKQWM ENQDCDEPAL YPCCSHWRFP YKQEVFELCI KRAIMELERS
TGYHLYSKTP GPRFDINDTI RAVVLEFQST YLFTLAYEKM HQFYREVDSW ISNELSSAPE
GLGNGWFVSN LEFYDLQDSL SDGTLIAMGL SVAVAFSVML LTTWNIIISL YAIVSIAGTI
FVTVGSLVLL GWELNVLESV TISVAVGLSV DFAVHYGVAY RLAPDPDREG KVIFSLSRMG
SAIAMAALTT FVAGAMMMPS TVLAYTQLGT FMMLIMCISW AFATFFFQCM CRCLGPQGTC
GQIPLPKKLQ CNIFSQALSG SQGDQGQNKA HPVNTFQLDS RGQKPEMEQE HYELEPLASH
TSNSNLSEKV SYEETHICSE LFNGRPPNSC MPVHSAYNSE LNKSNKNEAG STIVQPCIDQ
HPVCPFSSQN RQCSCPDAYR QLSDTLCYHC APSSGNVVQI QNSVPPVNVL QQAVESYVPP
VQHVLHCSCL QGRLKRPMMQ NSLPRNFFLH SVQQFQTHER INRRDPPSLQ NTEESIRTLP
KVTSSSPFIC RSAGSLIKPC SEAENNVSSN QKGLCKIRDK CDLRGTEVSE NEDKRTSVSM
QKKITEIKID LNPSQTGQLL KADQNDQKHI LNSTVREAGY ESCPENTQYC NRTITVKCNS
VDGHMPNIEA NVPALLTHPE LSSESLLIKT L
//
