ID A0A452GIV9_9SAUR Unreviewed; 1102 AA.
AC A0A452GIV9;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGAGP00000001540.1};
OS Gopherus agassizii (Agassiz's desert tortoise).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Testudinidae; Gopherus.
OX NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000001540.1, ECO:0000313|Proteomes:UP000291020};
RN [1] {ECO:0000313|Proteomes:UP000291020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28562605;
RA Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT "The Agassiz's desert tortoise genome provides a resource for the
RT conservation of a threatened species.";
RL PLoS ONE 12:e0177708-e0177708(2017).
RN [2] {ECO:0000313|Ensembl:ENSGAGP00000001540.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cell cortex
CC {ECO:0000256|ARBA:ARBA00004544}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR AlphaFoldDB; A0A452GIV9; -.
DR STRING; 38772.ENSGAGP00000001540; -.
DR Ensembl; ENSGAGT00000001756.1; ENSGAGP00000001540.1; ENSGAGG00000001234.1.
DR Proteomes; UP000291020; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01381; MYSc_Myo7; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 1.25.40.530; MyTH4 domain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR036106; MYSc_Myo7.
DR InterPro; IPR000857; MyTH4_dom.
DR InterPro; IPR038185; MyTH4_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR46049; AGAP003327-PA; 1.
DR PANTHER; PTHR46049:SF5; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 3; 1.
DR Pfam; PF00612; IQ; 2.
DR Pfam; PF00063; Myosin_head; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 2.
DR SMART; SM00242; MYSc; 1.
DR SMART; SM00139; MyTH4; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50096; IQ; 2.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51016; MYTH4; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000291020}.
FT DOMAIN 66..717
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 936..1102
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT REGION 596..618
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT BINDING 159..166
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1102 AA; 125547 MW; FAE9267383C532B9 CRC64;
MVILGKLGDH VWLESLSNSE FSVPIGAVVK ISDSGQILVE DDEGKEHWIT ARNINAVHPM
HPTSAQGVED MIRLGDLNEA GIVHNLLIRH QEHKIYTYTG SILVAVNPYQ VLPLYTVEQI
QLYSNKRIGE LPPHVFAIAD NCYFNMKRNK RDQCCVISGE SGAGKTESTK LILQFLAAIS
GQHSWIEQQI LEANPILEAF GNAKTIRNDN SSRFGKYIDI HFNRSSVIEG ARIEQFLLEK
SRVCRQALEE RNYHIFYCML MGMNLEQKKM LNLGTASEYT YLTMGDCTSC DGRNDAKEYA
HVRSAMKVLM FSDSEHWDIS KLLAAILHLG NVFPSSQAMS TSKILQRCLT NHSIIIRGES
VSMPLSVAQA ADGRDAFVKG IYGHLFLWIV NKINAAIFNP PSQDSKSLRR SIGLLDIFGF
ENFNTNSFEQ LCINFANEHL QQFFVRHVFK LEQEEYLAEH ISWSHIDFTD NHQALEVIAL
KPMNIVSLID EESKFPKGTD TTLLNKINSH HGKSKVYIPP RSVHDTKFGI NHFAGIVYYQ
SKGFLEKNRD MLSSNIMQLV YSSKNKFLRQ IFQVETTGSD TTKRLSTLGG QFKQSLEQLM
KILGSCQPYF IRCIKPNDYK KPLLFDRELC IRQLRYSGMM ETIRIRKAGY PMRYSFAEFF
ERYRVLLPMS AREQDDARRC CIYISEVILG KDEDWKIGRT KIFLKDYHDM VLEVQRDKAL
TEKAILIQKV LRGFKDSCIN SHQLFSSLGR QLAKQYKTAR ASVIKFQALC RGYLMRQKTA
EQMKAVGIIQ AYARGMFARR SFQRIKRELN MLLVNLNVSF VCLKEHLAML EREEEEEEKQ
RKHNALSNKP SLYDAISDQE MVDTVFGFLP TVIGGQEGQA PLGFEDLEAK AGKLDEVDLD
MIPMSMELEE EVDDLVEYTF PKFAATYFQG SSTHTHIRRP LRHPLLYHDE KDDILASLAV
WNIILRFMGE LPEPVMFAEN TNSKSSSVMT QIYDTLGKKS QVQLMSNNTP ELGVSSVKLK
RSSKLTGKVV SQLNSREELI QEQSTILDRP MSNLEKVHFV IGNAILHPLL QVASEALCQF
TPAEELAYTV HITGTCNAMG GE
//
