ID A0A452GJG2_9SAUR Unreviewed; 734 AA.
AC A0A452GJG2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Protein phosphatase 1 regulatory subunit 21 {ECO:0000256|ARBA:ARBA00020102};
DE AltName: Full=Coiled-coil domain-containing protein 128 {ECO:0000256|ARBA:ARBA00031617};
DE AltName: Full=KLRAQ motif-containing protein 1 {ECO:0000256|ARBA:ARBA00031361};
OS Gopherus agassizii (Agassiz's desert tortoise).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Testudinidae; Gopherus.
OX NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000001819.1, ECO:0000313|Proteomes:UP000291020};
RN [1] {ECO:0000313|Proteomes:UP000291020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28562605;
RA Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT "The Agassiz's desert tortoise genome provides a resource for the
RT conservation of a threatened species.";
RL PLoS ONE 12:e0177708-e0177708(2017).
RN [2] {ECO:0000313|Ensembl:ENSGAGP00000001819.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Early endosome {ECO:0000256|ARBA:ARBA00004412}.
CC Endosome {ECO:0000256|ARBA:ARBA00004177}.
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DR AlphaFoldDB; A0A452GJG2; -.
DR Ensembl; ENSGAGT00000002070.1; ENSGAGP00000001819.1; ENSGAGG00000001451.1.
DR Proteomes; UP000291020; Unassembled WGS sequence.
DR GO; GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
DR InterPro; IPR040024; PPP1R21.
DR InterPro; IPR049372; PPP1R21_C.
DR InterPro; IPR019343; PPP1R21_N.
DR InterPro; IPR019348; PPP1R21_six_helix.
DR PANTHER; PTHR21448:SF0; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 21; 1.
DR PANTHER; PTHR21448; SMOOTH MUSCLE MYOSIN HEAVY CHAIN-RELATED; 1.
DR Pfam; PF10205; KLRAQ; 1.
DR Pfam; PF21636; PPP1R21_C; 1.
DR Pfam; PF10212; PPP1R21_helical; 1.
DR SMART; SM01254; KLRAQ; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Reference proteome {ECO:0000313|Proteomes:UP000291020}.
FT DOMAIN 1..66
FT /note="Protein phosphatase 1 regulatory subunit 21 N-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM01254"
FT REGION 38..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 91..157
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 512..557
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 649..683
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 734 AA; 83798 MW; 82578DDCF8C53F1D CRC64;
MKDQSLRKLQ QEMDSLTFRN QQLAKRVELL QDELALSEAK GKKNKKSGDS SSQLSQEQKS
VFDEDLQKKI EENERLHIQF FEADERHKRL EAELKNRLEV LETDAAQHQA VVDSLTRKYI
DTIEKLQNDK TNLEIKSQTL EREAKECRFR AEECQQQLKN LHADLGRRLD DSLCIINEKV
PFNDTRSIQY NALNVPLHNR RCQLKLRDIA GQALAFVQDL VTALLNFHTY MEQRVQIFPI
DSATDTISPL NQKFSQYLHE NASYVRPLEE GMLHLFESIT EDTVTVLETT VKLKVFSEHL
TSYTCFLRKI LPYQLKSLEE ECESSLCTAA LRARNLELHN DMKKITAVFE KLHVYISLIV
LPSIRPEGLL RTNYSSVFTH IAAGLHGFHN VMKEVSKHYS QKAALEHELP TATQKLITTN
DCILSSVVAL TNGAGKIASF FSNNLDHFMA SLSYGPKGGT EFISPLSAEC MLQYKKKAVA
YMKSLKKPYS DSVPYEEALA NRRVLLSSTE SREGLAQQVQ QSLEKIAKLE QEKEHWMLEA
QLAKIKLEKE NQKLKSSLSG QLIEPMPENS VLLNAAEQEK EVSIKKTSGE PVKKMSLIGM
LTMTTGSKEA PEAKSREDLI KNHYMARIVE LTSLLQLADS KSVHFHAECR ALAKRLSLAE
KSKESLVEEM KLASQSISRL QDELTTTKRS YEDQLSMMSD HLCSMNETLS KQREEIDTLK
MSKVGYQVLY LLWA
//
