ID A0A452GZH2_9SAUR Unreviewed; 683 AA.
AC A0A452GZH2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Cadherin domain-containing protein {ECO:0000259|PROSITE:PS50268};
OS Gopherus agassizii (Agassiz's desert tortoise).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Testudinidae; Gopherus.
OX NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000007596.1, ECO:0000313|Proteomes:UP000291020};
RN [1] {ECO:0000313|Proteomes:UP000291020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28562605;
RA Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT "The Agassiz's desert tortoise genome provides a resource for the
RT conservation of a threatened species.";
RL PLoS ONE 12:e0177708-e0177708(2017).
RN [2] {ECO:0000313|Ensembl:ENSGAGP00000007596.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A452GZH2; -.
DR STRING; 38772.ENSGAGP00000007596; -.
DR Ensembl; ENSGAGT00000008768.1; ENSGAGP00000007596.1; ENSGAGG00000006074.1.
DR Proteomes; UP000291020; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 4.
DR Gene3D; 2.60.40.60; Cadherins; 5.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF118; PROTOCADHERIN BETA-1; 1.
DR Pfam; PF00028; Cadherin; 4.
DR Pfam; PF08266; Cadherin_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 5.
DR SUPFAM; SSF49313; Cadherin-like; 5.
DR PROSITE; PS00232; CADHERIN_1; 3.
DR PROSITE; PS50268; CADHERIN_2; 5.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Reference proteome {ECO:0000313|Proteomes:UP000291020};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..683
FT /note="Cadherin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019382005"
FT DOMAIN 27..134
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 135..243
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 244..348
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 349..453
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 454..563
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
SQ SEQUENCE 683 AA; 76048 MW; 25F593369E3261D2 CRC64;
MAAAALQRGL KRQVLSFFLC LCVSLGACET IRYSVPEEKK SGSLVANIAK DLKLDAGKLS
GRSARLISES SNKQYLELNT SSGDMIIKEK IDREDLCGQR DPCFLQFEIV LENPLQLYRM
EVQIDDVNDN SPKFSKNEFV LKIPEQLPVN SRFPLERAQD PDIGTNGIQS YAISSNEYFS
LDVHSRGDGS KYAELLLEKQ LDREEHAQLI LVLTAADGGL PQRTGTARIR VNVLDSNDNF
PQFSQSVYKV QLMENSPRDT LVTKVEASDL DQGLNAEITY SFGQVPDRVL KLFQLNPFTG
EITVLGIIDY EDAAMHEIEI HATDGGGLYA HCKVMVEIKD MNDNAPEVTL TSLTSTISEG
SSPETVVALF SVSDRDSRDN GRTLCSIQDN VPFALKSTLK NFYELVTQKP LDREKVPEYN
ITITATDRGT PRLTSVRVIR VQLSDINDNP PVFNESSYVM YLKENNPPGL LIGTVRAADL
DTEQNAKVTY SALPGNIGDL LLSSSISINS KNGKVYSLQS LDYEQRRDFQ VTVRAADGGF
PPLSSEVIVR VVIIDENDNA PFILYPLQNR VHSPAPPPAP LYCVIYKFVL YLVPLYQGTG
VLSVQTNPRH RRAKIDCSGI NILRLIWTQC IDPRARLHRF QNSINPNGVP ESTWRAADID
AAPSGWVSTS ILEIRLHLHY SRS
//
