ID A0A452GZP2_9SAUR Unreviewed; 543 AA.
AC A0A452GZP2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Spondin domain-containing protein {ECO:0000259|PROSITE:PS51020};
OS Gopherus agassizii (Agassiz's desert tortoise).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Testudinidae; Gopherus.
OX NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000007673.1, ECO:0000313|Proteomes:UP000291020};
RN [1] {ECO:0000313|Proteomes:UP000291020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28562605;
RA Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT "The Agassiz's desert tortoise genome provides a resource for the
RT conservation of a threatened species.";
RL PLoS ONE 12:e0177708-e0177708(2017).
RN [2] {ECO:0000313|Ensembl:ENSGAGP00000007673.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR AlphaFoldDB; A0A452GZP2; -.
DR STRING; 38772.ENSGAGP00000007673; -.
DR Ensembl; ENSGAGT00000008857.1; ENSGAGP00000007673.1; ENSGAGG00000005723.1.
DR Proteomes; UP000291020; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.2130; F-spondin domain; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 6.
DR InterPro; IPR009465; Spondin_N.
DR InterPro; IPR038678; Spondin_N_sf.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR InterPro; IPR044004; TSP1_spondin_dom.
DR NCBIfam; NF038123; NF038123_dom; 1.
DR PANTHER; PTHR11311; SPONDIN; 1.
DR PANTHER; PTHR11311:SF16; SPONDIN-1; 1.
DR Pfam; PF06468; Spond_N; 1.
DR Pfam; PF19028; TSP1_spondin; 1.
DR Pfam; PF00090; TSP_1; 5.
DR SMART; SM00209; TSP1; 6.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 6.
DR PROSITE; PS51020; SPONDIN; 1.
DR PROSITE; PS50092; TSP1; 6.
PE 4: Predicted;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000291020};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 1..124
FT /note="Spondin"
FT /evidence="ECO:0000259|PROSITE:PS51020"
FT REGION 467..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 543 AA; 61484 MW; 7A5F3E4BBC1E4144 CRC64;
MCHQKSQGAT ITWLEEAHQT ITGNLIFLFL ICRRAAPSAE FSVDRTRHLM SFLTMLGPSP
DWNVGLSAED LCTKDCGWVQ KVIQDLIPWD AGTDSGVTYE SPNKPTIPQE KIRPLTSLDH
PQSPFYDPEG GSIAVVARVV IERIARKGEQ CNIIPDNVDD IVADLVPEEK EEDDTPETCI
YSNWSPWSAC SSSTCDKGKR MRQRMLKAQL DLSVPCPDTQ DFQPCMGPGC SDEDGSTCMM
SEWITWSPCT VSCGMGMRSR ERYVKQFPDD GSMCKVPTEE TEKCIVNEEC SPSSCLVTEW
AEWNECSASC GIGMKKRHRM IKMTPADGSM CNTETTEVEK CMMPECHTIP CMLSPWSEWS
DCSVTCGKGM RTRQRMLKSA AELGDCNEEL EQVEKCMLPE CPIDCELTEW SKWSECNKSC
GKGHIIRTRM IKMEPQFGGA PCPETVQRKK CRIRKCLRGP SLEKRRWKEA REKRRSEHTK
EDVEGEPYPG CKMRPWTAWS ECTKLCGGGI QERFMTVKKR FKSTQFTSCK DKKEIRACNV
HPC
//
