ID A0A452HGU4_9SAUR Unreviewed; 1340 AA.
AC A0A452HGU4;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Titin {ECO:0008006|Google:ProtNLM};
OS Gopherus agassizii (Agassiz's desert tortoise).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Testudinidae; Gopherus.
OX NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000014092.1, ECO:0000313|Proteomes:UP000291020};
RN [1] {ECO:0000313|Proteomes:UP000291020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28562605;
RA Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT "The Agassiz's desert tortoise genome provides a resource for the
RT conservation of a threatened species.";
RL PLoS ONE 12:e0177708-e0177708(2017).
RN [2] {ECO:0000313|Ensembl:ENSGAGP00000014092.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR Ensembl; ENSGAGT00000016135.1; ENSGAGP00000014092.1; ENSGAGG00000010724.1.
DR Proteomes; UP000291020; Unassembled WGS sequence.
DR CDD; cd00063; FN3; 10.
DR CDD; cd05748; Ig_Titin_like; 3.
DR Gene3D; 2.60.40.10; Immunoglobulins; 14.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR14340; MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3; 1.
DR PANTHER; PTHR14340:SF13; TITIN; 1.
DR Pfam; PF00041; fn3; 9.
DR Pfam; PF07679; I-set; 4.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 10.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF49265; Fibronectin type III; 6.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50853; FN3; 10.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Reference proteome {ECO:0000313|Proteomes:UP000291020};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..82
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 88..184
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 188..277
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 284..378
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 381..474
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 478..564
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 573..666
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 672..755
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 761..856
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 862..955
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 960..1045
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1056..1151
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1231..1325
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
SQ SEQUENCE 1340 AA; 147695 MW; 3430E93B92EA1D8A CRC64;
MIVTWGRPVD NGGAEIEGYI LEKRDKDGIR WTKCHKKRLT DLRFRVTGLT DGHFYEFRVS
AENAAGVGES SEPSIFYRAC DALYPPGPPS NPKVTDTSRS SVSLAWSKPI YDGGAPIKGY
VVEVKEATAD EWITCTPPTG LQGKQFTVTK LKENNEYNFR ICAINSEGVG ESATIPGTVI
AADKIEPPEI ELDADLRKVV TVRASGTLRL FVTIKGRPEP EVKWEKAEGT ISDRAQIEVT
SSYTMLVIDN VNRFDSGRYN LTLENNSGKK SAFVNVRVLD SPSAPVNLTI REVKRDSVAL
AWEPPLIDGG AKITNYIIEK RESTRKAYAT VTNNCTKNTF KIDQLQEGCI YYFRVLAANE
YGVGLPAETA EPVKVSEPPY PPGKVTLVDV TRNTATITWE KPESDGGSKI TSYIVEMQTK
GSEKWSTCTQ VKTLEATITG LSKGEEYTFR VIAINEKGKS DPRQLGVPVV AKDIEIQPSA
ELLFNTFSVK AGDDLKIDVP IRGRPPPTAS WRKDGQTLKE TTRVNVQTSK TSTLLTIKEA
SKEDVGNYEL CISNSAGSTT FSITIIVLDR PGPPCDVHID SVSADNVTLS WKPPVYDGGC
HISNYIVEKR ETTTTIWDVV SAAVARTSIK VARLTTGSEY QFRVYAENRY GRSTYIESPS
VVAEYPFKPP GPPGTPQVVH ANKTFMTVSW QEPVNDGGSK TSRIAWTLCE GELRTTSCKV
TKLLRGNEYI FRVMGVNKYG VGEALESYAV KALDPFTVPN PPKSLEITSV TKDSMTLCWA
RPDSDGGNEI SGYIIERREK NSLRWIRVNK KPVYDLRVKS LGLREGCEYE YRVYAENAAG
LSLPSDTSPL IRAEDPVFIP SPPSKPKILD STRSNITIGW TKPLFDGGAP VTGYTVEYKK
TDETDWSIAI QNLRGTEYSV IGLTSGSEYV FRVRSINKVG ASDPSDVSEP QVAKEREEEP
AFDIDSEMRK TLIVKAGDSF TMTIPFRGKP VPNVMWNKPE TDLRTRASID SSDYCTSLTI
EKATRNDSGK YALTLQNVLS TATLTLVVKV LDSPGPPSNI AVKDVTKESA VLSWDVPEND
GGAPVKNYYI EKREASKKAW VTITNNCHRL SYKVTSLQEG AVYYFRVSGE NEFEQLGMFA
DTETQDEIVG SNLKVEIPIS GKPLPKMTLS RDGVPLKATM RFNTETTAES VIINLKESMA
GDAGRYDITA ANSSGTTKSF INIVVLDRPG PPVGPVVVSD ITEDSVTLKW QPPHNDGGSQ
VTNYIVLKRE TSTAVWSEVS ATVARSIIKV MKLTTGEEYQ FRIKAENRFG ISDHIDSQCV
TVKLPYSKSS VSHITFCCCF
//
