ID A0A452HHJ6_9SAUR Unreviewed; 765 AA.
AC A0A452HHJ6;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGAGP00000014364.1};
OS Gopherus agassizii (Agassiz's desert tortoise).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Testudinidae; Gopherus.
OX NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000014364.1, ECO:0000313|Proteomes:UP000291020};
RN [1] {ECO:0000313|Proteomes:UP000291020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28562605;
RA Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT "The Agassiz's desert tortoise genome provides a resource for the
RT conservation of a threatened species.";
RL PLoS ONE 12:e0177708-e0177708(2017).
RN [2] {ECO:0000313|Ensembl:ENSGAGP00000014364.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A452HHJ6; -.
DR STRING; 38772.ENSGAGP00000014364; -.
DR Ensembl; ENSGAGT00000016433.1; ENSGAGP00000014364.1; ENSGAGG00000010892.1.
DR Proteomes; UP000291020; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd16514; RING-HC_LONFs_rpt2; 1.
DR Gene3D; 2.30.130.40; LON domain-like; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR003111; Lon_prtase_N.
DR InterPro; IPR046336; Lon_prtase_N_sf.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR23327:SF5; LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 2; 1.
DR PANTHER; PTHR23327; RING FINGER PROTEIN 127; 1.
DR Pfam; PF02190; LON_substr_bdg; 1.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR SMART; SM00464; LON; 1.
DR SMART; SM00184; RING; 2.
DR SMART; SM00028; TPR; 3.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51787; LON_N; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000291020};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 259..295
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 472..510
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 558..758
FT /note="Lon N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51787"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 64..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..104
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..119
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 765 AA; 85442 MW; 6FB19E4CE7026D2B CRC64;
MSLQLLSRAR RGPFPSTQRG LQRRGALCSG ASPAQAFARH RAGSQPAGEG AARCHLRAAA
PHRRWAGDGT APGGGAAHTH YIINKPVPRG QRPRQEERAR QRRPPGRSLP GRRRGRAAWS
RGRGGPASEA GGMEPSPGPC AEMLQVAEEA FRGGNFELAA EIYGSQLAEL PQPERGLCLR
RGDALARAGR MAEALEAYSA AARLARLRPE ELRELAESLA LRLREKALRL PPWPAGGPEG
AGEALSDPAC CRPPELLGCP LCRRLLCEPV TLHCGHTRCR RCAEPGDCGR CPRPRRAADA
PGPASARVNV VLGNLLEKWL EGESRTRRLR AEGDELRDRQ ELPAALEKYN QALETAPCKC
SLIAQRAELW ITMKNYQQAL HDADALCQNK PLWPKGHYVK AQALSGLGRT EEALKEFLYC
VALNPEWSLM KKEAQKVHCS SPLDGDTVLE NSATSALREI PAVLVDASDF ECSLCMRLFY
EPVTTPCGHT FCLKCLERCL DHNPYCPLCK EKLSEFLASR TYKKTILTEE LIVRYLPEEL
SERKKVYEEE MKELSNLNED VPIFVCTMAF PTIPCPLHVF EPRYRLMIRR CMETGTKQFG
MCLADELKGF ADYGCMLEIR DVKFFPDGRS VVDTVGVRRF KVLNHGQRDG YNTANIEYLE
DKKVEGAEYE ELVHLHDSVY DQAVAWFTSL KDNMKAQILN HFGSMPGKES EPQSNPSGPA
WYWWLLAVLP LENRAQLAIL AMTSLKDRLI AIRRVLIFVT RKRPR
//
