ID   A0A452HLF5_9SAUR        Unreviewed;       233 AA.
AC   A0A452HLF5;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=MHC class I-like antigen recognition-like domain-containing protein {ECO:0000259|Pfam:PF00129};
OS   Gopherus agassizii (Agassiz's desert tortoise).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC   Testudinoidea; Testudinidae; Gopherus.
OX   NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000015791.1, ECO:0000313|Proteomes:UP000291020};
RN   [1] {ECO:0000313|Proteomes:UP000291020}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=28562605;
RA   Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA   Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT   "The Agassiz's desert tortoise genome provides a resource for the
RT   conservation of a threatened species.";
RL   PLoS ONE 12:e0177708-e0177708(2017).
RN   [2] {ECO:0000313|Ensembl:ENSGAGP00000015791.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Involved in the presentation of foreign antigens to the
CC       immune system. {ECO:0000256|ARBA:ARBA00002297}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC       pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC   -!- SIMILARITY: Belongs to the MHC class I family.
CC       {ECO:0000256|ARBA:ARBA00006909, ECO:0000256|RuleBase:RU004439}.
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DR   AlphaFoldDB; A0A452HLF5; -.
DR   STRING; 38772.ENSGAGP00000015791; -.
DR   Ensembl; ENSGAGT00000018027.1; ENSGAGP00000015791.1; ENSGAGG00000011875.1.
DR   Proteomes; UP000291020; Unassembled WGS sequence.
DR   Gene3D; 3.30.500.10; MHC class I-like antigen recognition-like; 1.
DR   InterPro; IPR011161; MHC_I-like_Ag-recog.
DR   InterPro; IPR037055; MHC_I-like_Ag-recog_sf.
DR   InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR   InterPro; IPR001039; MHC_I_a_a1/a2.
DR   PANTHER; PTHR16675:SF242; CLASS IB MHC ANTIGEN QA-2-RELATED; 1.
DR   PANTHER; PTHR16675; MHC CLASS I-RELATED; 1.
DR   Pfam; PF00129; MHC_I; 1.
DR   PRINTS; PR01638; MHCCLASSI.
DR   SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Immunity {ECO:0000256|ARBA:ARBA00022451};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   MHC I {ECO:0000256|ARBA:ARBA00022451};
KW   Reference proteome {ECO:0000313|Proteomes:UP000291020}.
FT   DOMAIN          31..205
FT                   /note="MHC class I-like antigen recognition-like"
FT                   /evidence="ECO:0000259|Pfam:PF00129"
SQ   SEQUENCE   233 AA;  27136 MW;  2725770821E45065 CRC64;
     LRDTFPGFSL GSLAGSLSLI HISPPTPPGF HSRRVLDTVV SEPGPGLPWY SRVVYVDDQV
     IYVYTSGMQR AEPRPVWMAQ NEGPEFWDER TWWAQRHQKW FKASLNTLGQ LYNQSKGFHI
     IQMKYGCDLR EDNTTWGFYQ DSYDGRDFLT FDTESMTLGA ADIGAQITKR RWDAEVFDNQ
     QWKRYLEERC IPWLRSSLEY GKETLQRKGK MGDKPYPEGH YKLYLHSPAP VPK
//