ID   A0A452HXD3_9SAUR        Unreviewed;       611 AA.
AC   A0A452HXD3;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Baculoviral IAP repeat containing 2 {ECO:0008006|Google:ProtNLM};
OS   Gopherus agassizii (Agassiz's desert tortoise).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC   Testudinoidea; Testudinidae; Gopherus.
OX   NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000019795.1, ECO:0000313|Proteomes:UP000291020};
RN   [1] {ECO:0000313|Proteomes:UP000291020}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=28562605;
RA   Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA   Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT   "The Agassiz's desert tortoise genome provides a resource for the
RT   conservation of a threatened species.";
RL   PLoS ONE 12:e0177708-e0177708(2017).
RN   [2] {ECO:0000313|Ensembl:ENSGAGP00000019795.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the IAP family. {ECO:0000256|ARBA:ARBA00006672}.
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DR   AlphaFoldDB; A0A452HXD3; -.
DR   STRING; 38772.ENSGAGP00000019795; -.
DR   Ensembl; ENSGAGT00000022557.1; ENSGAGP00000019795.1; ENSGAGG00000014596.1.
DR   Proteomes; UP000291020; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   CDD; cd00022; BIR; 3.
DR   CDD; cd08329; CARD_BIRC2_BIRC3; 1.
DR   CDD; cd16713; RING-HC_BIRC2_3_7; 1.
DR   CDD; cd14394; UBA_BIRC2_3; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR   InterPro; IPR001370; BIR_rpt.
DR   InterPro; IPR048875; BIRC2-3-like_UBA.
DR   InterPro; IPR041933; BIRC2/BIRC3_UBA.
DR   InterPro; IPR001315; CARD.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR001841; Znf_RING.
DR   PANTHER; PTHR10044:SF79; BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 2; 1.
DR   PANTHER; PTHR10044; INHIBITOR OF APOPTOSIS; 1.
DR   Pfam; PF00653; BIR; 3.
DR   Pfam; PF21290; BIRC2-3-like_UBA; 1.
DR   Pfam; PF00619; CARD; 1.
DR   Pfam; PF13920; zf-C3HC4_3; 1.
DR   SMART; SM00238; BIR; 3.
DR   SMART; SM00114; CARD; 1.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   SUPFAM; SSF57924; Inhibitor of apoptosis (IAP) repeat; 3.
DR   PROSITE; PS01282; BIR_REPEAT_1; 2.
DR   PROSITE; PS50143; BIR_REPEAT_2; 3.
DR   PROSITE; PS50209; CARD; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000291020};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          446..536
FT                   /note="CARD"
FT                   /evidence="ECO:0000259|PROSITE:PS50209"
FT   DOMAIN          564..599
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REGION          357..379
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          420..447
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        357..371
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   611 AA;  69220 MW;  7662881A69889CD9 CRC64;
     MNIVESSSFL ANLMNNSTVC ELKYELSCEL YRMSTFSTFP LNVPVSERSL ARAGFYYTGV
     KDKVKCFSCG LMLDNWKQGD CALEKHKQLY PSCSFVQNLL SVSNLGSSSH SAFSPPATIN
     SFSPSLHSIT GAPSLEQIGF FSTTFSSFPQ EPVTSRAVED PSHLRSNFYN PAMSTEDARL
     CTFQTWPLTF LSPTDLAKAG FYYTGPGDKV ACFTCGGQLS NWEPKDNAMS EHRRYFPNCP
     FVENKARGHP IFSISNQSMQ THVARVKTFI NWPTRIPVRP EQLANAGFYY VGRNDDVKCF
     CCDGGLRCWE SGDDPWIEHA KWFPRCEYLL RIKGREFVNQ IQARFPHLLE QLLSTSDTPV
     DESANPPTIH SESRESHSED AIMMNTPVVK AALEMGFSRR LIKQTVQSKI LATEENYKTV
     NDLVSDLLTA EDEKREEEKE RQSEEVASDD LSLIRKNRMA LFQHLTCVLP ILESLLSAKV
     ITELERDVIK QKTQTPLQAR ELIDMILVKG NAAAHIFRNC LRECDPMLYK DLFVEKNMKY
     VPTEDTLGLP MEEQLRRLQE ERTCKVCMDK EVSIVFIPCG HLVVCKECAP SLRKCPICRG
     TIKGTVRTFL S
//