ID A0A452HY89_9SAUR Unreviewed; 831 AA.
AC A0A452HY89;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Cadherin domain-containing protein {ECO:0000259|PROSITE:PS50268};
OS Gopherus agassizii (Agassiz's desert tortoise).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Testudinidae; Gopherus.
OX NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000020129.1, ECO:0000313|Proteomes:UP000291020};
RN [1] {ECO:0000313|Proteomes:UP000291020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28562605;
RA Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT "The Agassiz's desert tortoise genome provides a resource for the
RT conservation of a threatened species.";
RL PLoS ONE 12:e0177708-e0177708(2017).
RN [2] {ECO:0000313|Ensembl:ENSGAGP00000020129.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A452HY89; -.
DR STRING; 38772.ENSGAGP00000020129; -.
DR Ensembl; ENSGAGT00000022943.1; ENSGAGP00000020129.1; ENSGAGG00000014861.1.
DR Proteomes; UP000291020; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 6.
DR Gene3D; 2.60.40.60; Cadherins; 6.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF133; PROTOCADHERIN ALPHA-9; 1.
DR Pfam; PF00028; Cadherin; 5.
DR Pfam; PF08266; Cadherin_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 6.
DR SUPFAM; SSF49313; Cadherin-like; 6.
DR PROSITE; PS00232; CADHERIN_1; 4.
DR PROSITE; PS50268; CADHERIN_2; 6.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000291020};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..831
FT /note="Cadherin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019194682"
FT TRANSMEM 694..715
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 34..133
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 134..242
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 243..350
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 351..455
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 456..565
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 580..681
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REGION 796..831
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 831 AA; 90195 MW; 0BB0272FEE00D010 CRC64;
MALLCRDSLV TRQLLRLVLL HTAWEVGSGQ VRYSVPEESK HGTFVGRLAQ DLGLEVVELV
SRMFRMVSSG RRDYFEVNLQ SGVLFVNSRL DREELCGQSP LCAIDLEVIV DKPLRIFHVE
VEIQDINDNA PVFPVNELNL FISESRLPGS RFPLEGASDA DIGTNSLLTY KLSSNEYFTL
DVQVRNDHNK LAELGLKKAL DREETPEHIL LLTATDGGKP QLTGTVQLVI TVLDANDNAP
VFNQSVYEVT VLENTAKGTL VIKLNATDLD EGTNKNISYS FGNFVPPIVR AAFNLNSHTG
EIRVKGDLDY EHVELYEIRI EAQDKGHQPM TGQCSVLLHV LDVNDNAPEL AVTSLSLPVP
EDAPPGTVVA LISVSDRDSG DNGKVTCSIP PDLPFRLVST FKNYHSLVLA EAVDRERVSE
YKIVVTARDE GAPSLSASSS ILVAISDVND NAPAFPQPVY TVFVKENNPP GAHLLTVSAS
DPDLRENAFV SYSVVERSVG EQPLSSYISV HSESGHIYAL QPLDYEELQV LQFQVSARDA
GLPSLCGNVT VQLFVLDAND NAPAVSPAGS VRGSPGPELV PLSAGAGHVV GKIRAVDADS
GYNAWLRYEV QEPGAAGPFR VGVYSGEIST TRALEEADGP SQRLVILVKD HGEPALSATA
TVSLSLVESP QAVKWDLRPR GGSEVPLVDM NVSLMIAICS VSGLFVLVIV VYVGLRCHPG
PAVMCEPGKA TVVCASEVGS WAYSQRQSRN LCVGEGTRLE CECSCLMVRV RHMEPELGSK
SDTKPKVRAG VMCRAEKQGP GMSQERRNRE ASWIKMTGIR SRQKGRAQAS K
//
