ID   A0A452I130_9SAUR        Unreviewed;       749 AA.
AC   A0A452I130;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=FH2 domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Gopherus agassizii (Agassiz's desert tortoise).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC   Testudinoidea; Testudinidae; Gopherus.
OX   NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000021209.1, ECO:0000313|Proteomes:UP000291020};
RN   [1] {ECO:0000313|Proteomes:UP000291020}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=28562605;
RA   Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA   Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT   "The Agassiz's desert tortoise genome provides a resource for the
RT   conservation of a threatened species.";
RL   PLoS ONE 12:e0177708-e0177708(2017).
RN   [2] {ECO:0000313|Ensembl:ENSGAGP00000021209.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A452I130; -.
DR   STRING; 38772.ENSGAGP00000021209; -.
DR   Ensembl; ENSGAGT00000024155.1; ENSGAGP00000021209.1; ENSGAGG00000015579.1.
DR   Proteomes; UP000291020; Unassembled WGS sequence.
DR   Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR   InterPro; IPR015425; FH2_Formin.
DR   InterPro; IPR042201; FH2_Formin_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR45725; FORMIN HOMOLOGY 2 FAMILY MEMBER; 1.
DR   PANTHER; PTHR45725:SF10; FORMIN-LIKE PROTEIN 13; 1.
DR   Pfam; PF02181; FH2; 1.
DR   SMART; SM00498; FH2; 1.
DR   SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR   PROSITE; PS51444; FH2; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000291020}.
FT   DOMAIN          184..295
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          374..749
FT                   /note="FH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51444"
FT   COILED          644..710
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   749 AA;  85909 MW;  2928E0CEABD14F03 CRC64;
     MGTDETNRSF AAMDNTRTQD TIPQLSQEKI LKIMNMVKNK DLSIEGALDL AQKEMHAEKE
     AMNMAFPMDS QDLLTGSQFN FSVYKYKRYR WQKRILQIDF NTETIFNIEK GIIKKQFPFS
     QVKSYEDSEG RRFSIAFHER ADYELEAMSL EDKRKISHLV NKVTRSNSYR RPAVSCSGRP
     AKGDVIHEGL LDLQQDSFAS IKWVKYLVQL SEGELSLSCI GNNGENKNAD PVAKTINLSD
     GNVSIVKENG YDTFSVQTKE HNYLFRIPFT VQNNRAEDIS KLQNEWVSLI DRYCMLWKKH
     SEPQDGFGEG TSEAVYEKLI ISPNKQAEGA HCLAVGSEAP PRSIPFREQT TPGSSFPLSR
     VQAVVPPPPS FPPPSRPSPA WKRTKAFHWD VVPQDKIQKS IWASCSRHKK KIDESRIYDQ
     FHIQDMVIFS GNEPSVNRHI MLNQKIAHTF NIFLKSFHIK PNQLKEKLYI LHEDGGGLTD
     EQITALRRYL PTPKDLEMYQ SFKGSPAELH VVDQFMLEMC KIPHLGQRLD LLLTIRELPV
     CMGDLEPLIN QKIRACKELQ TSQKFVAVLE YILAIGNYLN EKAGREMAKG FQLSSLTKLS
     LLRGKERKIT LLHALVEQII LHEPDLAKFS QELTEFEAVP GASIKGLRAE VDVLKKELEN
     VIQYRKFIKS KTIKTTTQES QFYKELKDLI QKYEGHLSQL SKRCDEMKKL YADTLVKFGE
     SPDQDSQELF GWISAFIREF RKVSADIMS
//