ID A0A452I196_9SAUR Unreviewed; 985 AA.
AC A0A452I196;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Dynamin-type G domain-containing protein {ECO:0000259|PROSITE:PS51718};
OS Gopherus agassizii (Agassiz's desert tortoise).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Testudinidae; Gopherus.
OX NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000021226.1, ECO:0000313|Proteomes:UP000291020};
RN [1] {ECO:0000313|Proteomes:UP000291020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28562605;
RA Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT "The Agassiz's desert tortoise genome provides a resource for the
RT conservation of a threatened species.";
RL PLoS ONE 12:e0177708-e0177708(2017).
RN [2] {ECO:0000313|Ensembl:ENSGAGP00000021226.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A452I196; -.
DR Ensembl; ENSGAGT00000024174.1; ENSGAGP00000021226.1; ENSGAGG00000015590.1.
DR Proteomes; UP000291020; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR CDD; cd09913; EHD; 1.
DR Gene3D; 1.10.268.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR031692; EHD_N.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43681:SF1; SARCALUMENIN; 1.
DR PANTHER; PTHR43681; TRANSMEMBRANE GTPASE FZO; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR Pfam; PF16880; EHD_N; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000291020}.
FT DOMAIN 602..843
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 43..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 511..552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..117
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..179
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..195
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..234
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 321..362
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 363..393
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 416..441
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 452..468
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 476..491
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 531..552
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 985 AA; 107414 MW; 7C3EDAC6B8F752B8 CRC64;
MPHDCGSKTG ADINIPVDGL NNDSQEEDND MNIANAASSV SECGAATGSN ADGSETVARE
TEPAEGTPLP GEDMEELLAK EQPGGSRNEA AKESKEEKEL HVAGVEIRLE EAGRKENRQN
SPPASAGSFE ESTRLPAEER QVSQRGTKTL AREEVAAAER HSGPDDGKDA ADKESEVSEA
SQRSAPPSPA SRESPSQGDA HRAEPALAEP GTLEEVGTQL EEGSKEDKSR IPHASQGAES
HMQGGNHANK QDKEVSGSET SHVSGAPLGG NGLAAKEKEP DSDNRTGDSP VGETTTDGQA
AERDREEPST ASAEAVGENP NLEAEESEES SEEEDDDQEE SEEESDDSAE EEGDDSAEEE
KEAAGLAEEK GGDPTEAEEE GAGLAKEEEE GAGLVEGAGL AEEESGHLAE TEGAGLAEEE
GGDPAEEEGG DPAEAEEEAE EVIAPDVRVA ASDMGDHGHV KEEEISGVEA ESDSAGQKNA
PRRDMEQDKA HSHNSNPAVA GSLSVDAQLV AETDSPPGNN HLPAAAVPDP RQIEETEDVG
ETAKRDRSHI ESTLKLSEAK PADDYSATLQ RLRKIYHSSI KPLEQSYRYN ELRQHEITDG
EITSKPMVLF LGPWSVGKST MINYLLGLDD TPYQLYTGAE PTTSEFTVIM HGPKLKTIEG
IVMAADSARS FSPLEKFGQN FLEKLIGIEV PHKLLERVTF VDTPGIIENR KQQERGYPFN
DVCQWFIDRA DLIFVVFDPT KLDVGLELEM LFRQLKGRES QIRIILNKAD SLATQELMRV
YGALFWSLAP LINVTEPPRV YVSSFWPPEY HPETHKDLFL KEEISLLEDL NQVIENRLEN
KIAFIRQHAI RVRIHALLVD RYLQTYKDKM TFFSDGELVF KDIVEDPDKF YIFKSILAKT
NVSKFDLPNR EAYKDFFGIN PISSFKLLAQ QCSYMGGCYL EKIERAITHE LPDLLGSIGL
GKKPSILSCD TTGCGETPRN RYRKP
//
