ID A0A452I522_9SAUR Unreviewed; 492 AA.
AC A0A452I522;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGAGP00000022676.1};
OS Gopherus agassizii (Agassiz's desert tortoise).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Testudinidae; Gopherus.
OX NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000022676.1, ECO:0000313|Proteomes:UP000291020};
RN [1] {ECO:0000313|Proteomes:UP000291020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28562605;
RA Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT "The Agassiz's desert tortoise genome provides a resource for the
RT conservation of a threatened species.";
RL PLoS ONE 12:e0177708-e0177708(2017).
RN [2] {ECO:0000313|Ensembl:ENSGAGP00000022676.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TOM1 family. {ECO:0000256|ARBA:ARBA00007708,
CC ECO:0000256|PIRNR:PIRNR036948}.
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DR AlphaFoldDB; A0A452I522; -.
DR STRING; 38772.ENSGAGP00000022676; -.
DR Ensembl; ENSGAGT00000025831.1; ENSGAGP00000022676.1; ENSGAGG00000016624.1.
DR Proteomes; UP000291020; Unassembled WGS sequence.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR CDD; cd14236; GAT_TOM1; 1.
DR CDD; cd16995; VHS_Tom1; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR014645; TOM1.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR13856:SF32; TARGET OF MYB PROTEIN 1; 1.
DR PANTHER; PTHR13856; VHS DOMAIN CONTAINING PROTEIN FAMILY; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR PIRSF; PIRSF036948; TOM1; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR036948};
KW Reference proteome {ECO:0000313|Proteomes:UP000291020};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR036948}.
FT DOMAIN 20..152
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 215..303
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT REGION 164..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 455..492
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 478..492
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 492 AA; 53970 MW; 067EA7898B7F140C CRC64;
MEFLLGSPFS SPVGQRIEKA TDGSLQSENW ALNMEICDII NETEEGPKDA FRAIKKRIVG
NKNFHEVMLA LTVLETCVKN CGHRFHVLVA SQDFVESVLV RIILPKNNPP TIVHDKVLTL
IQSWADAFRS SPDLTGVVAV YEDLRRKGLE FPMTDLDMLS PIHTPQRTVY GSDSPSEQNS
PAGDSPQGVD SILHPVSLPG GPGASSDTPI TPTPEQIGKL HSELEVVNGN VKVMSEMLTE
LVPGQAEPSD LELLQELNRT CKAMQQRVLE LIPRILHEQL TEELLIVNDN LNNVFLRYER
FERLRAGQPI KVPIEVENSW INTGPSAPLI DKQPEATNSL SSQLAGINLG SGSVSAGLQS
LNSSGKLEEE FDMFALTRGS SLAEQRKEVK YEDPQANKGL AGALDARQQS TGAIPVPQAG
FMEDIEQWLS TDVGEETEEA KGVTSEEFDK FLEERAKVAD QLPALPSPRA GPPTASSPHR
KQEKKDDTMF AL
//
