ID A0A452IB23_9SAUR Unreviewed; 726 AA.
AC A0A452IB23;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=RAB GTPase activating protein 1 like {ECO:0008006|Google:ProtNLM};
OS Gopherus agassizii (Agassiz's desert tortoise).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Testudinidae; Gopherus.
OX NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000024926.1, ECO:0000313|Proteomes:UP000291020};
RN [1] {ECO:0000313|Proteomes:UP000291020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28562605;
RA Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT "The Agassiz's desert tortoise genome provides a resource for the
RT conservation of a threatened species.";
RL PLoS ONE 12:e0177708-e0177708(2017).
RN [2] {ECO:0000313|Ensembl:ENSGAGP00000024926.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR Ensembl; ENSGAGT00000028373.1; ENSGAGP00000024926.1; ENSGAGG00000018223.1.
DR Ensembl; ENSGAGT00000028412.1; ENSGAGP00000024959.1; ENSGAGG00000018223.1.
DR Ensembl; ENSGAGT00000028413.1; ENSGAGP00000024960.1; ENSGAGG00000018223.1.
DR Proteomes; UP000291020; Unassembled WGS sequence.
DR CDD; cd01211; PTB_Rab6GAP; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR Gene3D; 1.10.10.750; Ypt/Rab-GAP domain of gyp1p, domain 1; 1.
DR Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR InterPro; IPR022164; Kinesin-like.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR InterPro; IPR000195; Rab-GAP-TBC_dom.
DR InterPro; IPR035969; Rab-GAP_TBC_sf.
DR PANTHER; PTHR47219; RAB GTPASE-ACTIVATING PROTEIN 1-LIKE; 1.
DR PANTHER; PTHR47219:SF7; RAB GTPASE-ACTIVATING PROTEIN 1-LIKE; 1.
DR Pfam; PF12473; DUF3694; 1.
DR Pfam; PF00640; PID; 1.
DR Pfam; PF00566; RabGAP-TBC; 1.
DR SMART; SM00462; PTB; 1.
DR SMART; SM00164; TBC; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 1.
DR PROSITE; PS01179; PID; 1.
DR PROSITE; PS50086; TBC_RABGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000291020}.
FT DOMAIN 135..250
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT DOMAIN 539..725
FT /note="Rab-GAP TBC"
FT /evidence="ECO:0000259|PROSITE:PS50086"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 462..504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 726 AA; 82401 MW; A0CCA03772E53918 CRC64;
MEVRSSFDKF SQSSESVSTL NSEEFVLVHQ QPEDPHAKDE KPQLKIFSNG DEQLEKAMEE
ILRDSEKCQI NYVTDCKDSS DACRQSAEDV SASQTNQPSL HLILDPSTTE ISAPRPCSPN
ELSEEDSVLF NKLMYLGSMK VSAPRSESEA LRAMEALKSS CQSSFPVTLY VPNIPEGSVR
IIDQTSNTEI ASFPIYKILF CARGQNGTAE SDCFTFTESY CGTEEFQIHV FSCEIKEAVS
RILYSFSTAF RRSSKQASDY VKDSVLPTTD SDVFTFSVSL EVKEDDGKGN FSPVPKDREK
FYFKLKQGID KKVVITVQQL SNKELAIERC FGMLLSPGRN VKNSDMHLLD MESMGKSCDG
RAYVITGMWN PNAPTFLVLN EETPKDKRVY MTVAVDMVVT EVVEPVRFLL ETVVRVYPAN
ERFWYFSRKT FTETFYMKLK QSEGKSHTNA GDAIYEVVSL QRESERDDES VSPTSRGGPL
SPQEDEAEEE SDNELSSGTG DVSKDCPEKV LYSWGELLGR WHNNLAVRPK GLSTLVKSGV
PEALRAEIWQ LLAGCHDNQA MLDKYRILIT KDSVQESVIT RDIHRTFPAH DYFKDTGGDG
QESLYKICKA YSVYDEDIGY CQGQSFLAAV LLLHMPEEQA FCVLVKIMYD YGLRDLYKNN
FEDLHCKFYQ LEKLMQEQLP DLYSHFSDLN LEAHMYASQW FLTLFTAKFP LCMVFHIIDL
LLCEVK
//
