ID A0A452IC31_9SAUR Unreviewed; 1362 AA.
AC A0A452IC31;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=USP domain-containing protein {ECO:0000259|PROSITE:PS50235};
OS Gopherus agassizii (Agassiz's desert tortoise).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Testudinidae; Gopherus.
OX NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000025251.1, ECO:0000313|Proteomes:UP000291020};
RN [1] {ECO:0000313|Proteomes:UP000291020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28562605;
RA Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT "The Agassiz's desert tortoise genome provides a resource for the
RT conservation of a threatened species.";
RL PLoS ONE 12:e0177708-e0177708(2017).
RN [2] {ECO:0000313|Ensembl:ENSGAGP00000025251.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR Ensembl; ENSGAGT00000028747.1; ENSGAGP00000025251.1; ENSGAGG00000018416.1.
DR Proteomes; UP000291020; Unassembled WGS sequence.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR CDD; cd02661; Peptidase_C19E; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR018200; USP_CS.
DR InterPro; IPR028889; USP_dom.
DR PANTHER; PTHR21646; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR PANTHER; PTHR21646:SF39; UBIQUITINYL HYDROLASE 1; 1.
DR Pfam; PF00443; UCH; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00972; USP_1; 1.
DR PROSITE; PS00973; USP_2; 1.
DR PROSITE; PS50235; USP_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000291020}.
FT DOMAIN 110..418
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 62..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 453..632
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 910..1040
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1184..1327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..83
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..613
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 910..1012
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1184..1209
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1210..1226
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1227..1247
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1248..1262
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1281..1318
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1362 AA; 153547 MW; 43338ED661E3B338 CRC64;
MTIVDRVSES SNPAACQKQP CSSVVPSTGD MDSASASWGA VSSLEVPKHK ITLGPVPGAA
VYSSSSVPDK SKPSAQKDQS ISDGIAPPQK VLFPAEKICL KWQQTHRVGA GLQNLGNTCF
LNSALQCLTY TPPLANYMLS HEHSKTCHEQ GFCMMCTMQA HITQALSNSG NVIKPMAVIN
DLRRIAKHFR FGNQEDAHEF LRYTVDAMQK ACLNGSNKLD RHTQATTLIY QIFGGYLRSR
VKCMNCKGVS DTFDPYLDIT LEIKTAQSVN KALEQFVKPE QLDGENAYKC SKCKKMVPAS
KRFTIHRSSN VLTLSLKRFA NFSGGKITKV HKMVIWIFDH ICLXDIRPYM SQPNGEPIIY
VLYAVLVHTG FSCHAGHYYC YIKASNGQWY QMNDSVVSNS DIRSVLNQQA YVLFYIRSHD
MKNGGEHAHS IHTPGQSSPR PVISQRVVNS RQGASGFIGP QLPPHMIKNS SHLNGTGSLK
ETPSSSVASA SNITLNRPAS APPSTSIQNW TINRPTIPDP SKKQKITISI HNNKLPTHQT
LSQPNLHNSL ENLSKPVPSS TITNSSAVKS TSSAPTSVAT KVSKQTTPSE SCSKPLMNGK
SKLNSSTLVP YGAESSEESD EESKGLVKEN GHSNSFNGIL IGNVVSTLQN SCSSCQDAEE
VVSQHELPKN VTVNGAISID SDPEENGLKF DEPTCQVKPV KSAEIPFSKV NGLHGKIIPT
ALPPVPEDRI LESFRYNQLK SLSEEISATG LEKTSENDCH IETLVSGNNT VPYEKSSKVP
ANLSCNVQTP FTTSDAETIS TKEEIAESIV SKTDNCDPKD YADKIRGTQE VKMTLKESPL
HIRGSAETAE KLGQSPFLKS DSECSSKKLA ALNIIDECQE TKESANNYTD VLPTNDSSAA
RLDKVLESHY SKENDGLDGN EICEENKDRQ KFKSHSPVKE KNCTPKKTDK GHYRTKRERS
ESEEQEKQTK RKPDDDYSRK RQSYSKESMK QDRYKQEHCN GNKYKLMHSE RNSPDNGRSL
GKYTYYRSRS RGKTDQERSR YYHSKRERSW SRERYYQDIP RRWDKCRYYN DYHPSYTARD
GRERKFFHGD RDYDKSSQVY NSRSYRDYYY TSRWNHEPIA KEREKHHFGS SKIDLYNCSV
PSQHSEKYSH EKCASMSEEN NSSFEMSCHK YEYLKDRKRK CASLEGSDSD MEKKHRRSLE
SEPTEEQKMK KHKKSKKKKK SKDKHREKDE RHHQDSDFSG ACSDSDIHKH KKKKKKKKKH
TKKSEGFIDY LDPNIQKDAG SETKTWEKKE FHCTDDPPSE EYSKHGSKWP HAGGDADSCH
KTKYIGGGQE NSYHVSKEYS KGKRSLEING ISIFSNREKY LK
//
