ID A0A452IDU1_9SAUR Unreviewed; 1035 AA.
AC A0A452IDU1;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
OS Gopherus agassizii (Agassiz's desert tortoise).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Testudinidae; Gopherus.
OX NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000026043.1, ECO:0000313|Proteomes:UP000291020};
RN [1] {ECO:0000313|Proteomes:UP000291020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28562605;
RA Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT "The Agassiz's desert tortoise genome provides a resource for the
RT conservation of a threatened species.";
RL PLoS ONE 12:e0177708-e0177708(2017).
RN [2] {ECO:0000313|Ensembl:ENSGAGP00000026043.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A452IDU1; -.
DR STRING; 38772.ENSGAGP00000026043; -.
DR Ensembl; ENSGAGT00000029619.1; ENSGAGP00000026043.1; ENSGAGG00000019022.1.
DR Proteomes; UP000291020; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd05763; IgI_LRIG1-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR45842:SF19; LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS PROTEIN 2; 1.
DR PANTHER; PTHR45842; SYNAPTIC ADHESION-LIKE MOLECULE SALM; 1.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 3.
DR Pfam; PF01463; LRRCT; 1.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 3.
DR SMART; SM00365; LRR_SD22; 7.
DR SMART; SM00369; LRR_TYP; 11.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50835; IG_LIKE; 3.
DR PROSITE; PS51450; LRR; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000291020};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 773..799
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 468..567
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 572..661
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 666..755
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 980..1009
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1035 AA; 116554 MW; BE0449D37F2B0A4F CRC64;
MDNMFQKKKK NESGFELLVN FSETTCHVQH NYLGPDYRII SYFSLFSRDL SHNHLLSSNW
SIDLSNHTLQ EVKMNYNELS EIPYFGEPTA NITILSLVHN TIPQINAEQL ELYLSLENLD
LSSNLISEIK AASFPRMQLK YLNLSNNRIT TLEAGCLDNL SSSLVVVKLN RNRISMIPPK
VFKLPHVQFL ELKRNRIKIV ESLTFQGLES LKSLKMQRNG ISKLMDGAFF GLDNMEELEL
EHNNLTEINK GWLYGLRTLQ QLYVSQNAIN RISPDAWEFC QRLSELDLSY NQLTRLDESA
FAGLGLLEKL NLGDNRIVHI ADGVFKGLSN LQTLDLRNNE IFWAIEDSNE AFAGLSSLNK
LILQGNQIKS ITKKAFSGLE ALEHLDLNNN AIMSIQENAF AQTHFSELML NTSSLLCDCQ
LKWLLQWLVD SHLQQDVNVS CAHPEWLAGQ SILNVNPEDF VCDDFPKPQI RVHPESAIAL
KGINVTLTCT AVSTSDSPMS TAWRKDSEIL YDAEVENFAR YQQQDGEVLE YTTVLHLFNV
NFTDEGKYQC IVTNHFGSNY SNKAKLTVNE LPSFLKTPMD LTIRTGAMAR LECAAEGHPS
PQISWQKDGG TDFPAARERR MHVMPEDDVF FIANVKIEDM GIYSCMAQNI AGGLSANATL
TVLETPSFVR PLEDRTVTRG ETAVLQCIAG GSPAPRLNWT KDDGPLTVTE RHFFAAANQL
LIIVDAGLED AGKYTCIMSN TLGTERGHIY LNVLSSQNCD SSQSGILHEE DGWTTVGIVI
IVVVCCVVGT SLVWVIVIYH MRRKSEDYSI TNTEEMNLPA DIPSYLSSQG TLSEPQEGYS
NSEAGSHQQL MPPANGYVHK GADSGTGPLV ICSDCYDNAN IYSRTREYCP YAYITEEDPL
DHTLSSLMVQ VPKETYPTDT QHEARILDNL IVDREMSAFL THHDRINEKK LSSQQTNNEP
FQLPLWGLNR DIGLAHSRFP KQQSIREEAP QGLRSEGVID GEREQAVSPR PCHRLREHNL
DFNRTRNIQE FSKAT
//
