ID A0A452IH49_9SAUR Unreviewed; 1247 AA.
AC A0A452IH49;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=USP domain-containing protein {ECO:0000259|PROSITE:PS50235};
OS Gopherus agassizii (Agassiz's desert tortoise).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Testudinidae; Gopherus.
OX NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000027315.1, ECO:0000313|Proteomes:UP000291020};
RN [1] {ECO:0000313|Proteomes:UP000291020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28562605;
RA Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT "The Agassiz's desert tortoise genome provides a resource for the
RT conservation of a threatened species.";
RL PLoS ONE 12:e0177708-e0177708(2017).
RN [2] {ECO:0000313|Ensembl:ENSGAGP00000027315.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A452IH49; -.
DR STRING; 38772.ENSGAGP00000027315; -.
DR Ensembl; ENSGAGT00000031026.1; ENSGAGP00000027315.1; ENSGAGG00000019859.1.
DR Proteomes; UP000291020; Unassembled WGS sequence.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR CDD; cd02659; peptidase_C19C; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 2.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR018200; USP_CS.
DR InterPro; IPR028889; USP_dom.
DR PANTHER; PTHR24006; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR PANTHER; PTHR24006:SF842; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 40; 1.
DR Pfam; PF00443; UCH; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00972; USP_1; 1.
DR PROSITE; PS00973; USP_2; 1.
DR PROSITE; PS50235; USP_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000291020}.
FT DOMAIN 41..494
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT REGION 17..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1247 AA; 141617 MW; 69F3B3B3AD38B8AC CRC64;
MFGDLFEENF SFVSNNQCGK GKKSKSKDTE PPAPREFTKL SGIKNQGGTC YLNSLLQTLH
FTPEFREALF SLGPEELGSL EDINKPDIKV RIIPLQLQRL FAQLLLLDQQ AASTTDLTES
FGWNSNEEMR QHDVQELNRI LFSALETSLV GTSGHDLINR LYHGTVVNQI VCKECKNVSE
RQEDFLDLTV AVKDVSGLEE ALWNMYVEEE YFENDNLYRC GTCNKLVEAA KSAKLRKLPP
FLTVSLLRFN FDFEKCERYK ETSCYTFPIR INLRPFCEQT HLEDLEYMYE LFSVIIHKGG
CYGGHYHVYI KDVDALGNWQ LQEEESKLMT EEKMQKDTEN IKEMENPLTI LKGIISEEES
KQIPVDQLGQ KLLEKKGMSW NKKYRKQYGP IRKYLQNHSQ IFQLSPDDNK VSLKEMYHQL
QFGSDCRGQV LQSPSQNSDV QWTSESLCTV LKDSTSGSHW FDLNDSKVQP IKEKDIEKQF
QGKESAYMLF YRKSQLKRPS EAQANPRYRV PGHLLNEMDA ANIELRKRRV DSDSADNNID
LHLHLGSHYK LYNGALHPSL SWKESVLDLT IDKRKTLGDL RQSIFQLLEF WEGDMILSTA
KSLPAGLHVY QTLDGDEMTL GGTGLADGAD VFVWNGKEVG GMEVLPGLDH EPVLLNVLRL
AGYNEGGKGQ HFIESQHVVP CNAELSTLWK ALASPGGIIL MNISGSDKEV ENWKVIPEED
MKKTVRIVGL TDGSSILVLD SHDQSLVNVA SGNLTAFMHD ISWLQVKNFC QLEAEEKQVK
ITATVETVMS DIKIKAIQEL RLGEELVDDS CLRPINGNGK LLSPVPEDYT VKEAELKMGS
LLGLCHGKAP NSTQLFLYFV IGSDLQGTPE MEIVVEETAS VRECLNLMLE KSGLPGENWH
LRRLDWCYEA GEALSKEGAR LRELNVCSGD TLVITEGKLP PKGFLKVPIW WYKPLIHFGQ
QESTQDQVNC MTCMMGALQV SPAGDSPAYV QSDIRLCYAG DVEISGEAFL EDLKIQAMTL
PFFQELSVPS PEFLRAWTLE SKRPGKLLRN NQQQLNEYKL GGRTEICIEP LQKEENLGPS
DLLLRVQMGI PGERDYYHSV DLVWDTSKEC TAWALRHKLA AHYSLPVEKI EIAKYFPEKF
EWMTISSWTQ QISKRKRKKK QESLQSAPFH LKDGDIIGVK NLLLEEGKDF STVRDDIGKE
TQRQLAMEKK KSRQAQRLQN DVLSEGKVAT KHRKPEVALS INVGIFR
//
