ID A0A452IHW7_9SAUR Unreviewed; 2922 AA.
AC A0A452IHW7;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 10-FEB-2021, entry version 13.
DE SubName: Full=Centromere protein F {ECO:0000313|Ensembl:ENSGAGP00000027368};
OS Gopherus agassizii (Agassiz's desert tortoise).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudines; Cryptodira; Durocryptodira; Testudinoidea;
OC Testudinidae; Gopherus.
OX NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000027368, ECO:0000313|Proteomes:UP000291020};
RN [1] {ECO:0000313|Ensembl:ENSGAGP00000027368, ECO:0000313|Proteomes:UP000291020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28562605;
RA Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT "The Agassiz's desert tortoise genome provides a resource for the
RT conservation of a threatened species.";
RL PLoS ONE 12:e0177708-e0177708(2017).
RN [2] {ECO:0000313|Ensembl:ENSGAGP00000027368}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2019) to UniProtKB.
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DR Ensembl; ENSGAGT00000031091; ENSGAGP00000027368; ENSGAGG00000019901.
DR GeneTree; ENSGT00730000111187; -.
DR Proteomes; UP000291020; Unassembled WGS sequence.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 1.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 2.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000291020}.
FT DOMAIN 1..291
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 1932..2069
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2170..2309
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2771..2814
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 193..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2702..2754
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2901..2922
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 13..96
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 104..131
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 162..189
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 271..312
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 320..386
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 402..443
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 479..527
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 530..599
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 603..641
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 670..704
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 893..941
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 949..983
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1023..1043
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1083..1117
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1122..1142
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1176..1203
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1211..1252
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1311..1338
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1410..1437
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1570..1635
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1658..1680
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1824..1844
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1859..1879
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1887..1907
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1950..2040
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2062..2117
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2146..2299
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2304..2324
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2404..2431
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2480..2518
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2527..2575
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2590..2627
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2635..2669
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2676..2696
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 208..262
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2702..2722
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2723..2754
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2922 AA; 339760 MW; 5DB0C7FED534B95A CRC64;
MSWVVEEWKE GLSPRALQKI QELESQLDKL KKERQQRQFQ LESLEAALQK QKQKVENEKN
EGATLKRENQ SLMELCDNLE KTKQKISHDL QVKESQVNYQ AGQLTSSKKQ IERLEQELKR
YKSELERSQQ TLITGDLSLS STPQKNFTAP LTPNQNHNDS KFEELQEKYS KEVEERKRLE
AELRNIQVKK INHSHPQSTK SHREIARHQA SSTVFSWQQE KTSNCPSSSN QETPLKRGFT
SSHFPWEQEA TPSHSGLRSK KTDFNNSFSD NFELRSRVEE LEHQLQDQEK EKKFHMNKLQ
ETQLQLEKTK LEFTEKDSVL HKIRDELNRM TAQCDQTAAQ YEMVEQKMKK LSEELNCQRQ
NAESALRSLE QKVKEKEKEY QKELFRQQHS LQTADQQCNQ IKAKLNQDVQ QAKNDYNAVR
AELDKAVAVK QHLENDSSEL KQKLCRAEQA LLANQSKEND LRRNFEEMKK EKNLLCCQSD
QKSREIHQLE EELKTAKQFL KETQNYAEEM KNKSLSQEEN LKILQEKLKQ QDASLTLEKL
KLSIADLEKQ RDSIQHLLKQ RENHTEELNS KISKMEKESE ALLKVLRLKE RECEELKKEF
TILFQWKNEN EQLVNKLESE KEELLSKIND LESSLKIQQV KSNENSETVR IMVNEKELYC
LEIKNLRDMV EYKSAKLETQ KKAYDELQQE AECSDQKYRK EIENMTWKIS QFTIQVEILE
QKLQLAANAV QEKDQCYHEL HGEHEKICCL VKSKEISEVR EDREFHFQNN HCKIDDQQLP
VKNCITDVLM REPGTVTEDW EDHCAKPVLE TDKNDQQDMS VLQDQVSSPE ISLMAQSQFK
SHLQKPFEKL VQIKVETEKK LIEAEQMHES FVTETKNHIS NLQGDTSAQQ DCVDKTLAAL
EEKEKQLQTL NKELETQQAE IRDLKSNNKL LEDSVKQLQL VLDTWNLEKK DMSTMLSLHE
KEIEDLTEEN VTLKGINKAL EQEKVDLLET NIIFSNRLKE REESISELSR RHKEERLSLI
EGYEEIEKEL VDLQGKYKSM EEKSTNMEGI LRQQKSHFQK SKAKSERQEK QLRDEHNEFF
SKLVSLEGKN KDLIQELEKV QSELQFKQSE IAHIQNVSSA ELDCLRQEML NVRAEQNKMQ
EQHNILLQEN EQLSKVMKTE TECVTCDLVH DRGPTSEQLR VSMEEKENEL NKYQVKLELL
QMDLEDREVS VENYSTQVIQ LEAALKRVER KLEESEKEKE RLQQELQTIK EDLETPDPKL
IIMDKNDQTM ESVVDSISEV SSKRAIDERY SLVPHELTPS QNDDVQLISS LQMTVNRLNE
LEKMCEILQI EKLALTSELN DSKTECTTTD KMTEEVIKVV SEVKILKDEK AIFPDELMDQ
SVENEVGIHF DNEQMSFKSL ECSAEPNYSY EDLKLSNKEV KMRFAEVKEK IFSLQKEHKI
LHEQHCSMLF KVSELQSCIE TLKAENSALS TSLNKVSADS VEVQVTSRQK DGEFKLEETK
STFSPSCLNE MPYFAEANLL ELSFDNDLWK WREKSMRLNI SQESVLGDTT EISLVEEPQN
DQALDFIAKR ESIIQRKSNL ESNIKELQIL CQTYEKSIKR FEEQFQSREN MKNEIQELKQ
LIISERKELD DLRKQNVSDN EQWQQKLSNV TMEMEYKLAA EKKQVEHLSL ELEVARLQLQ
GLDLSSRSLL CTDVEDTSLT AQENNGIYQL QVHSLPNENL APKREKSEIK LCEQITIEEN
SECENVAEVT EARSAEECPA KLMSETEYRN TLEKKIDCHN ELSFSNNSIS TTPLDFMENQ
VTDETLQLQI NKTSSEDLKL LLGIEESNTK VDALLIEIKE LNSRLDLQHT ELTAKITAYA
ELEKTVLVLK KENSNLNEKL ESVSFDKQQI SYKIMILEKE LDKAKSDLDV YKVILSDVTD
MLEDLEVTKG VWHEKFLVTE NELRRTKSEK ENIENHALSI EGDIEELQRK NQKLEKDIEN
KLKTVSTLQE QLAVIIMERN QLSQELSILS EKKEELDQLY QKLQEKIKEL ESNKVDATEF
IGILEAEAKT QTKLLQTTKS DVDHLSREKD YLVQQLQNVE KEAEILTLEK EKFQNQMQDL
EEEKKLILRE SEMLQTKLSE SEMESSKLSK TLEGSLIEKG ELAARLNSTQ EEVDQLRYGI
EKLKIKIESD EKKKHRTVEK LKESERKADF LQDKIEKLER ELHMSEENLE DAILQAETAK
TEAETLKTEM EEMAERVKSL EFAVNAFRSE KEGLNKELQE KQEKISELES SNADVVRLLE
EKEKENMQIK EESENVTILI KSQLKNASEE IKLFFNELEI CKAKEQDLIH QVGCLEHDKT
QLLLDLQEAR NISTKLEQSL GALVQELADC KQTRDETIQE NGALQKIKDV EQLSVQLSHA
ESEHKCWMQE KEGLQNMIAE LKQKVQQLSN NEILKATLEN LKASPKDLEK ESTQSEKSAL
VEKIQLDLTT SGKNEPNKSL DGVQKELEKK EREMKKEISE YQSRFHQIEK NHQALLAEAN
RKNEVEIQAC QEKLNSLEQC LGEQKLEMEL LKSSKEQLNN SLKDANQTIE ELKKVQVDNL
KHIVQLKKQN AFARRKMEMS MKSCKQLEKE KEMLQKQIAE HDALLKKQKP SADEVSSAEE
MRLKLEELKE SVEEKTKEAE ENLEKYCTLI INYYKLEEAN EMLKTQVSLL NALLKQPANA
VNSLSQNSDN PVTLNNQSVT EKRSNEDPTK LSGKRQRCQE TKEVDGEPKS PIPETLSKKI
KKGAIYQHSL THENKEYEPD GLPETVKKGF ADIPIEKISP YVLRRTTLNL RTSPHLAAQS
QRLSPCAQSL QKGRSDNLAE ISKLTAGGSK SPKENDTQQC QAETTIEPME SLSRSPLRMN
KQLPKAVAET CRENLNTHKG RCSFSRKTLP DQNEQEENCM VQ
//
