ID   A0A452IS28_9SAUR        Unreviewed;       751 AA.
AC   A0A452IS28;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=PID domain-containing protein {ECO:0000259|PROSITE:PS01179};
OS   Gopherus agassizii (Agassiz's desert tortoise).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC   Testudinoidea; Testudinidae; Gopherus.
OX   NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000030824.1, ECO:0000313|Proteomes:UP000291020};
RN   [1] {ECO:0000313|Proteomes:UP000291020}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=28562605;
RA   Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA   Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT   "The Agassiz's desert tortoise genome provides a resource for the
RT   conservation of a threatened species.";
RL   PLoS ONE 12:e0177708-e0177708(2017).
RN   [2] {ECO:0000313|Ensembl:ENSGAGP00000030824.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A452IS28; -.
DR   Ensembl; ENSGAGT00000034956.1; ENSGAGP00000030824.1; ENSGAGG00000022157.1.
DR   Proteomes; UP000291020; Unassembled WGS sequence.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   CDD; cd01215; PTB_Dab; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR048559; DAB1/2_SBM.
DR   InterPro; IPR048561; Dab_PTB.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR006020; PTB/PI_dom.
DR   PANTHER; PTHR47695:SF5; DISABLED HOMOLOG 2; 1.
DR   PANTHER; PTHR47695; PID DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF21792; DAB2_SBM; 1.
DR   SMART; SM00462; PTB; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS01179; PID; 1.
PE   4: Predicted;
KW   Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW   Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW   Reference proteome {ECO:0000313|Proteomes:UP000291020}.
FT   DOMAIN          46..179
FT                   /note="PID"
FT                   /evidence="ECO:0000259|PROSITE:PS01179"
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          271..310
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          410..429
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          532..658
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          686..751
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..19
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..37
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        286..302
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        532..592
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        606..637
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        719..738
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   751 AA;  81127 MW;  B1A780C303A9CD62 CRC64;
     MSNEVETTNI NNQPEQQAVP KAPASKKEKK KGSEKTDEFL LARFKGDGVR YKAKLIGIDD
     VPEARGDKMS QDSMMKLKGM AVAARSQGQH KQKIWVNISL SGIKIIDEKT GVIEHEHPVN
     KISFIARDVT DNRAFGYVCG GEGQHQFFAI KTAQQAEPLV VDLKDLFQVI YNIKKKEEED
     KKKNGSDALT DQVDKIKLGV DQMDLFGDMS TPPDLNSPTE SKDILLVDLN SEIENNQTCV
     KESPFLNGIT SSLPRPKSQT PFLPESSLST NLSFFPIPNP DPFSDDPFTQ PDQSAQPSFD
     SLKSPHQKKE SLSFLGNGAV NGDIDYFGKE FDQISNRTGK QEIQTSQWPL ESKPMQLAAR
     TQNGVPEREQ NGFLTKSSSN LFAESPSKGL SLQNGVKLDS ESNVQFMSHD SITISPPPQS
     TKPGRGRRTV QTAANDLFSS DLFASTATEA PGLTSPAAQP ALVQTNPLDL FRTSPTIAPM
     AGLGGLPATA PTPWSQQSSV FNPATSVFPG SIMGAQSSGF TQPLAFSAPQ AASGWSQPAS
     FGAPSQSSGL WGQPAHVSPT AAWAQPSTIG KPFQTSMFPS TTQPSAMLSS VSAPSPPQPP
     PRTAPQKEPS KKESDAFTSL DPLGDKEKKD VKEMFKDFQL TKPPAVPARR GEQQQSRLGA
     SGAFTNYFNS KVGILQDNAD HDDLAANQLS IKISEPPKPA PRQSTLPASK PDALFENPFQ
     TDPFSTSQPS TVSRPSLSSD LFGDPFGNPF A
//